Unlike almost all other molecules the self-assembly of oligonucleotides can be programmed to fold into predesigned structures with high fidelity. In particular the development of the methods for DNA origami and DNA-tile assembly has allowed us to form highly complex self-assembled structures. Furthermore, by integrating strand-displacement reactions dynamic DNA structures can be formed.

Immobilization and physical properties of conjugated polymers in DNA structures.
New methods for immobilization of proteins in DNA nanostructures.
Formation of complex 3D structures for drug delivery.
Chemical stabilizing DNA nanostructures.

Researcher on this project