BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//TYPO3/NONSGML News system (news)//EN
BEGIN:VEVENT
UID:news-10052@inano.au.dk
DTSTAMP:20240312T082450Z
DTSTART:20240322T091500Z
DTEND:20240322T100000Z
END:VEVENT
END:VCALENDAR




<div class="news news-single">
	<div class="article" itemscope="itemscope" itemtype="http://schema.org/Article">
		
	
			<script type="text/javascript">
				const showAllContentLangToken = "Show all content ";
			</script>

			
			

			<article class="typo3-delphinus delphinus-gutters">

				<!-- News PID: 4816 - used for finding folder/page which contains the news / event -->
				<!-- News UID: 10052 - the ID of the current news / event-->

				<div class="news-event">
					<div class="news-event__header">
						<!-- Categories -->
						
							<span class="text--stamp">
<!-- categories -->
<span class="news-list-category">
	
		
	
		
	
</span>

</span>
						

						<!-- Title -->
						<h1 itemprop="headline">Distinguished iNANO lecture by Professor Bianxiao Cui, Stanford University</h1>
						

							<!-- Teaser -->
							<p class="text--intro" itemprop="description"><p>Membrane curvature drives integrin-mediated cell adhesion and mechanotransduction</p></p>
						
					</div>

					
						<!-- Top image -->
						
					

					<div class="news-event__content">

						<!-- Events info box -->
						
								

								<div class="news-event__info theme--dark" id="event-info">
									<h2 class="screenreader-only">Info about event</h2>

									
											<!--- Same date -->
											<div class="news-event__info__item news-event__info__item--time">
												<h3 class="news-event__info__item__header text--label-header">Time</h3>
												<div class="news-event__info__item__content">
													<span class="u-avoid-wrap">
														Friday 22  March 2024,
													</span>
													<span class="u-avoid-wrap">
														&nbsp;at 10:15 -  11:00
													</span>
													<p class="news-event__info__item__ical-link"><a href="/about/news-events/news/show/artikel/distinguished-inano-lecture-by-professor-bianxiao-cui-stanford-university?tx_news_pi1%5Bformat%5D=ical&amp;type=9819&amp;cHash=92d72b07894b6bbbb5e2fb9a3a032a56">Add to calendar</a></p>
												</div>
											</div>
										

									<!-- Location detailed -->
									
											<!-- Location Simple -->
											
												<div class="news-event__info__item">
													<h3 class="news-event__info__item__header text--label-header">Location</h3>
													<div class="news-event__info__item__content">
														<p>iNANO AUD (1593-012)</p>
													</div>
												</div>
											
										

									<!-- Organizer detailed -->
									
											<!-- Organizer Simple -->
											
												<div class="news-event__info__item">
													<h3 class="news-event__info__item__header text--label-header">Organizer</h3>
													<div class="news-event__info__item__content">
														Professor Mingdong Dong (dong@inano.au.dk)
													</div>
												</div>
											
										

									<!-- Price -->
									

									<!-- Event link -->
									

									<!-- Registration -->
									
								</div>
							

						
							<!-- Media -->
							
								



							
						

						
							<div class="news-event__content__text">
								<span class="text--byline" id="byline">
									

									<!-- Author -->
									
										<span itemprop="author" itemscope="itemscope" itemtype="http://schema.org/Person">
											
													By
												

											
													<a href="mailto:trinemh@inano.au.dk">
														<span itemprop="name">Trine Møller Hansen</span>
													</a>
												
										</span>
									
								</span>

								

									<!-- Body text -->
									<h2><a href="https://chemistry.stanford.edu/people/bianxiao-cui" target="_self">Professor Bianxiao Cui,&nbsp;Department of Chemistry,&nbsp;Stanford University</a> </h2>
<p><strong>Membrane curvature drives integrin-mediated cell adhesion and mechanotransduction</strong></p>
<p>Membrane curvature in the range of tens to hundreds of nanometers is involved in many essential cellular processes. Membrane curvatures in living cells are often below optical resolution and are highly dynamics, making it a technical challenge to explore curvature-initiated signaling events. We use nanofabrication to engineer vertical nanostructures to precisely manipulate the location, degree, and sign (positive or negative) of the interface curvature in live cells. We found that these membrane curvatures drastically affect intracellular signaling on the plasma membrane. Very recently, we found that membrane curvature promotes the formation of a new type of integrin ɑVβ5-mediated cell adhesions – curved adhesions. Curved adhesions are molecularly distinct from focal adhesions and clathrin lattices and are prevalent in soft fiber matrices in 3D. The findings illustrate molecular basis for the strong molecular connection between membrane topography and intracellular signaling.</p>
								
							</div>
						
					</div>

					
						<!-- Content elements -->
						
					
				</div>
			</article>

			
				
				
			

			<!-- related things -->
			
		

	</div>
</div>