Jørgen Kjems

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Zou, L., Luo, Y., Chen, M., Wang, G., Ding, M., Petersen, C. C., Kang, R., Dagnaes-Hansen, F., Zeng, Y., Lv, N., Ma, Q., Le, D. Q. S., Besenbacher, F., Bolund, L., Jensen, T. G., Kjems, J., Pu, W. T. & Bünger, C. (2013). A simple method for deriving functional MSCs and applied for osteogenesis in 3D scaffolds. Scientific Reports, 3, Article 2243. https://doi.org/10.1038/srep02243

Zhou, X., Rahimi, K., Kjems, J. & Lin, L. (2023). High-resolution RNA isoform variation analysis by combining the advantages of single-cell RNA and nanopore sequencing. 44. Abstract from Neuroscience Day, Aarhus, Denmark.

Zhang, Z., Olsen, E. M., Kryger, M., Voigt, N. V., Tørring, T., Gültekin, E., Nielsen, M., MohammadZadegan, R., Andersen, E. S., Nielsen, M. M., Kjems, J., Birkedal, V. & Gothelf, K. V. (2011). A DNA tile actuator with eleven discrete states. Angewandte Chemie International Edition, 50(17), 3983-7. https://doi.org/10.1002/anie.201007642

Zhang, X., Galenkamp, N. S., Heide, N. J. V. D., Valero Moreno, J., Maglia, G. & Kjems, J. (2023). Specific Detection of Proteins by a Nanobody-Functionalized Nanopore Sensor. ACS Nano, 17(10), 9167-9177. https://doi.org/10.1021/acsnano.2c12733

Zhang, X., Malle, M. G., Thomsen, R. P., Sørensen, R. S., Sørensen, E. W., Hatzakis, N. S. & Kjems, J. (2024). Deconvoluting the Effect of Cell-Penetrating Peptides for Enhanced and Controlled Insertion of Large-Scale DNA Nanopores. A C S Applied Materials and Interfaces, 16(15), 18422-18433. https://doi.org/10.1021/acsami.3c18636

Zhang, X., Hitt, P., Wanunu, M. & Kjems, J. (2026). Scalable Production of DNA-Probe-Functionalized Heteromeric MspA Nanopores for Biosensing. ACS Applied Materials and Interfaces, 18(10), 14531-14539. https://doi.org/10.1021/acsami.5c21011

Zahler, A. M., Damgaard, C. K., Kjems, J. & Caputi, M. (2004). SC35 and hnRNPs A/B binding to a juxtaposed ESE/ESS element regulates HIV-1 tat exon 2 splicing. Journal of Biological Chemistry, 279, 10077-10084.

Zahler, A. M., Damgaard, C. K., Kjems, J. & Caputi, M. (2004). SC35 and heterogeneous nuclear ribonucleoprotein A/B proteins bind to a juxtaposed exonic splicing enhancer/exonic splicing silencer element to regulate HIV-1 tat exon 2 splicing. Journal of Biological Chemistry, 279(11), 10077-10084. https://doi.org/10.1074/jbc.M312743200

Zaheer, S., Baindoor, S., Connolly, N. M. C., Siebenbrodt, K., Bauer, S., Rosenow, F., Andersen, J. S., Venø, M. T., Kjems, J., Henshall, D. C. & Prehn, J. H. M. (2025). Temporal Dynamics of tsRNA Regulation Mark an Abrupt Transition After Epileptogenesis. Journal of Neurochemistry, 169(12), Article e70317. https://doi.org/10.1111/jnc.70317

Zadegan, R. M., Jepsen, M. DE., Thomsen, K. E., Okholm, A. H., Schaffert, D. H., Andersen, E. S., Birkedal, V. & Kjems, J. (2012). Construction of a 4 Zeptoliters Switchable 3D DNA Box Origami. A C S Nano, 6(11), 10050-10053. https://doi.org/10.1021/nn303767b

Yu, M., Wang, J., Mura, M., Meng, Q.-Q., Xu, W., Gersen, H., Lægsgaard, E., Stensgaard, I., Kelly, R. E. A., Kjems, J., Linderoth, T. R., Kantorovich, L. N. & Besenbacher, F. (2011). Homochiral Xanthine Quintet Networks Self-Assembled on Au(111) Surfaces. ACS Nano, 5(8), 6651-6660. https://doi.org/10.1021/nn202157m

Yoshimoto, R., Rahimi, K., Hansen, T. B., Kjems, J. & Mayeda, A. (2020). Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats. iScience, 23(7), Article 101345. https://doi.org/10.1016/j.isci.2020.101345

Yang, C., Gao, S. & Kjems, J. (2014). Folic Acid Conjugated Chitosan for Targeted Delivery of siRNA to Activated Macrophages in vitro and in vivo. Journal of Materials Chemistry B, 48, 8608-8615. https://doi.org/10.1039/C4TB01374C

Yang, C., Nilsson, L., Cheema, M. U., Wang, Y., Frøkiær, J., Gao, S., Kjems, J. & Nørregaard, R. (2014). Chitosan/siRNA Nanoparticles Targeting Cyclooxygenase Type 2 Attenuate Unilateral Ureteral Obstruction-induced Kidney Injury in Mice. Theranostics, 5(2), 110-123. https://doi.org/10.7150/thno.9717

Yang, C., Thomsen, R. P., Ogaki, R., Kjems, J. & Mian Teo, B. (2015). Ultrastable green fluorescence carbon dots with a high quantum yield for bioimaging and use as theranostic carriers. Journal of Materials Chemistry B, 3(4577), 4577-4584. https://doi.org/10.1039/C5TB00467E

Yang, C., Ogaki, R., Hansen, L., Kjems, J. & Mian Teo, B. (2015). Theranostic carbon dots derived from garlic with efficient anti-oxidative effects towards macrophages. R S C Advances, 118, 97836-97840. https://doi.org/10.1039/C5RA16874K

Yang, C., Gao, S., Dagnæs-Hansen, F., Jakobsen, M. & Kjems, J. (2017). Impact of PEG Chain Length on the Physical Properties and Bioactivity of PEGylated Chitosan/siRNA Nanoparticles in Vitro and in Vivo. A C S Applied Materials and Interfaces, 9(14), 12203-12216. https://doi.org/10.1021/acsami.6b16556

Yang, C., Vu Quang, H., Husum, D. M. U., Tingskov, S. J. H., Vinding, M. S., Nielsen, T., Song, P., Nielsen, N. C., Nørregaard, R. & Kjems, J. (2017). Theranostic poly(lactic-co-glycolic acid) nanoparticle for magnetic resonance/infrared fluorescence bimodal imaging and efficient siRNA delivery to macrophages and its evaluation in a kidney injury model. Nanomedicine: Nanotechnology, Biology and Medicine, 13(8), 2451–2462. https://doi.org/10.1016/j.nano.2017.08.007

Yang, C., Gao, S., Song, P., Dagnæs-Hansen, F., Jakobsen, M. V. & Kjems, J. (2018). Theranostic Niosomes for Efficient siRNA/microRNA Delivery and Activatable Near-Infrared Fluorescent Tracking of Stem Cells. A C S Applied Materials and Interfaces, 10(23), 19494–19503. https://doi.org/10.1021/acsami.8b05513

Yan, Y., Wang, X., Venø, M. T., Bakholdt, V., Sørensen, J. A., Krogdahl, A., Sun, Z., Gao, S. & Kjems, J. (2017). Circulating miRNAs as biomarkers for oral squamous cell carcinoma recurrence in operated patients. OncoTarget, 8(5), 8206-8214. https://doi.org/10.18632/oncotarget.14143

Yan, Y., Chang, C. C., Venø, M. T., Mothershead, C. R., Su, J. & Kjems, J. (2019). Isolating, Sequencing and Analyzing Extracellular MicroRNAs from Human Mesenchymal Stem Cells. Journal of visualized experiments : JoVE, 2019(145), Article e58655. https://doi.org/10.3791/58655

Yan, Y., Chang, C., Su, J., Venø, M. T. & Kjems, J. (2020). Osteoblastogenesis Alters Small RNA Profiles in EVs Derived from Bone Marrow Stem Cells (BMSCs) and Adipose Stem Cells (ASCs). Biomedicines, 8(10), 1-17. Article 387. https://doi.org/10.3390/biomedicines8100387

Yan, Y., Gu, T., Christensen, S. D. K., Su, J., Lassen, T. R., Hjortbak, M. V., Lo, I., Venø, S. T., Tóth, A. E., Song, P., Nielsen, M. S., Bøtker, H. E., Blagoev, B., Drasbek, K. R. & Kjems, J. (2021). Cyclic hypoxia conditioning alters the content of myoblast-derived extracellular vesicles and enhances their cell-protective functions. Biomedicines, 9(9), Article 1211. https://doi.org/10.3390/biomedicines9091211

Xu, S., Dong, M., Liu, X., Howard, K. A., Kjems, J. & Besenbacher, F. (2007). Direct force measurements between siRNA and chitosan molecules using force spectroscopy. Biophysical Journal, 93(3), 952-9. https://doi.org/10.1529/biophysj.106.093229

Xu, W., Wang, J.-G., Jacobsen, M. F., Mura, M., Yu, M., Kelly, R. E. A., Meng, Q.-Q., Lægsgaard, E., Stensgaard, I., Linderoth, T. R., Kjems, J., Kantorovich, L. N., Gothelf, K. V. & Besenbacher, F. (2010). Supramolecular porous network formed by molecular recognition between chemically modified nucleobases guanine and cytosine. Angewandte Chemie International Edition, 49(49), 9373-7. https://doi.org/10.1002/anie.201003390

Xu, W., Tan, Q., Yu, M., Sun, Q., Kong, H., Lægsgaard, E., Stensgaard, I., Kjems, J., Wang, J., Wang, C. & Besenbacher, F. (2013). Atomic-scale structures and interactions between the guanine quartet and potassium. Chemical Communications, 49(65), 7210-7212. https://doi.org/10.1039/c3cc43302a

Wu, K., Song, W., Zhao, L., Liu, M., Yan, J., Andersen, M. Ø., Kjems, J., Gao, S. & Zhang, Y. (2013). MicroRNA functionalized microporous titanium oxide surface by lyophilization with enhanced osteogenic activity. A C S Applied Materials and Interfaces, 5(7), 2733-44. https://doi.org/10.1021/am400374c

Wittenborn, T., Nygaard, J. V., Horsman, M. R., Vorup-Jensen, T., Kjems, J., Thim, T., Nielsen, T., Larsen, E. K. U. & Falk, E. (2009). A Novel in Vivo Angiogenesis Mouse Model. Arteriosclerosis, Thrombosis, and Vascular Biology, (7).

Wittenborn, T., Nielsen, T., Nygaard, J. V., Larsen, E. K. U., Thim, T., Rydtoft, L. M., Vorup-Jensen, T., Kjems, J., Nielsen, N. C., Horsman, M. R. & Falk, E. (2012). Ultra-High-Field DCE-MRI of Angiogenesis in a Novel Angiogenesis Mouse Model. Journal of Magnetic Resonance Imaging, 35(3), 703-710. https://doi.org/10.1002/jmri.22855

Wittenborn, T. R., Larsen, E. K. U., Nielsen, T., Rydtoft, L. M., Hansen, L., Nygaard, J. V., Vorup-Jensen, T., Kjems, J., Horsman, M. R. & Nielsen, N. C. (2014). Accumulation of nano-sized particles in a murine model of angiogenesis. Biochemical and Biophysical Research Communications, 443(2), 470-6. https://doi.org/10.1016/j.bbrc.2013.11.127

Wiklund, E. D., Bramsen, J. B., Hulf, T., Andersen, L. D., Ramanathan, R., Hansen, T. B., Villadsen, S. B., Gao, S., Ostenfeld, M. S., Borre, M., Peter, M. E., Ørntoft, T. F., Kjems, J. & Clark, S. J. (2011). Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer. International Journal of Cancer, 128(6), 1327-1334. https://doi.org/10.1002/ijc.25461

Wiklund, E. D., Gao, S., Hulf, T., Sibbritt, T., Nair, S., Costea, D. E., Villadsen, S. B., Bakholdt, V., Bramsen, J. B., Sorensne, J. A., Krogdahl, A., Clark, S. J. & Kjems, J. (2011). MicroRNA Alterations and Associated Aberrant DNA Methylation Patterns across Multiple Sample Types in Oral Squamous Cell Carcinoma. PLoS One, 61(1), e27840 (1-11). http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0027840

Wiklund, E. D., Kjems, J. & Clark, S. J. (2010). Epigenetic architecture and miRNA: reciprocal regulators. Epigenomics, 2(6), 823-40. https://doi.org/10.2217/epi.10.51

Wedge, E., Ahmadov, U., Hansen, T. B., Gao, Z., Tulstrup, M., Côme, C., Nonavinkere Srivatsan, S., Ahmed, T., Jespersen, J. S., Schlotmann, B. C., Schöllkopf, C., Raaschou-Jensen, K., Ødum, N., Kjems, J., Bak, R. O., Walter, M. J., Grønbæk, K. & Kristensen, L. S. (2023). Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms. Leukemia, 37(5), 1113-1125. https://doi.org/10.1038/s41375-023-01866-4

Vu-Quang, H., Vinding, M. S., Nielsen, T., Ullisch, M. G., Nielsen, N. C. & Kjems, J. (2016). Theranostic Tumor Targeted Nanoparticles Combining Drug Delivery with Dual Near Infrared and (19)F Magnetic Resonance Imaging Modalities. Nanomedicine: Nanotechnology, Biology and Medicine, 12(7), 1873-1884. https://doi.org/10.1016/j.nano.2016.04.010

Vu-Quang, H., Vinding, M. S., Nielsen, T., Ullisch, M. G., Nielsen, N. C., Nguyen, D. T. & Kjems, J. (2019). Pluronic F127-folate coated super paramagenic iron oxide nanoparticles as contrast agent for cancer diagnosis in magnetic resonance imaging. Polymers, 11(4), Article 743. https://doi.org/10.3390/polym11040743

Vu-Quang, H., Vinding, M. S., Jakobsen, M., Song, P., Dagnaes-Hansen, F., Nielsen, N. C. & Kjems, J. (2019). Imaging rheumatoid arthritis in mice using combined near infrared and ¹⁹F magnetic resonance modalities. Scientific Reports, 9, Article 14314. https://doi.org/10.1038/s41598-019-50043-0

Vu Quang, H., Vinding, M. S., Xia, D., Nielsen, T., Ullisch, M. G., Dong, M., Nielsen, N. C. & Kjems, J. (2016). Chitosan-coated Poly(lactic-co-glycolic acid) Perfluorooctyl Bromide Nanoparticles for Cell Labeling in 19F Magnetic Resonance Imaging. Carbohydrate Polymers, 136, 936-944. https://doi.org/10.1016/j.carbpol.2015.09.076

Vu Quang, H., Chang, C.-C., Song, P., Hauge, E. M. & Kjems, J. (2018). Caveolae-mediated mesenchymal stem cell labelling by PSS-coated PLGA PFOB nano-contrast agent for MRI. Theranostics, 8(10), 2657-2671. https://doi.org/10.7150/thno.23206

Voigt, N. V., Tørring, T., Rotaru, A., Jacobsen, M. F., Ravnsbæk, J. B., Subramani, R., Mamdouh, W., Kjems, J., Mokhir, A., Besenbacher, F. & Gothelf, K. V. (2010). Single-molecule chemical reactions on DNA origami. Nature Nanotechnology, 5(3), 200-203. https://doi.org/10.1038/nnano.2010.5

Vogt, S., Bobbili, M. R., Stadlmayr, G., Stadlbauer, K., Kjems, J., Rüker, F., Grillari, J. & Wozniak-Knopp, G. (2021). An engineered CD81-based combinatorial library for selecting recombinant binders to cell surface proteins: Laminin binding CD81 enhances cellular uptake of extracellular vesicles. Journal of Extracellular Vesicles, 10(11), Article e12139. https://doi.org/10.1002/jev2.12139

Vinther, M. & Kjems, J. (2016). Interfacing DNA nanodevices with biology: Challenges, solutions and perspectives. New Journal of Physics, 18(8), Article 085005. https://doi.org/10.1088/1367-2630/18/8/085005

Vinther, S. C., Resag, A., Le, K. T. T., Zelle-Rieser, C. C., Strandt, H., Malle, M. G., Christiansen, S. H., Del Frari, B., Stigger, T., Schilling, B., Wohlfarth, J., Thiel, S., Valero, J., Stoitzner, P. & Kjems, J. (2026). Targeting Langerhans cells using a modular mannosylated nucleic acid-based vaccine platform. Journal of Controlled Release, 392, 114741. Article 114741. https://doi.org/10.1016/j.jconrel.2026.114741

Villadsen, S. B., Bramsen, J. B., Ostenfeld, M. S., Wiklund, E. D., Fristrup, N., Gao, S., Hansen, T. B., Jensen, T. I., Borre, M., Orntoft, T. F., Dyrskjøt, L. & Kjems, J. (2012). The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer. B J C, 106(2), 366-374. https://doi.org/10.1038/bjc.2011.520

Vieira de Sá, R., Sudria-Lopez, E., Cañizares Luna, M., Harschnitz, O., van den Heuvel, D. M. A., Kling, S., Vonk, D., Westeneng, H. J., Karst, H., Bloemenkamp, L., Varderidou-Minasian, S., Schlegel, D. K., Mars, M., Broekhoven, M. H., van Kronenburg, N. C. H., Adolfs, Y., Vangoor, V. R., de Jongh, R., Ljubikj, T. ... Pasterkamp, R. J. (2024). ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes. Nature Communications, 15(1), Article 7484. https://doi.org/10.1038/s41467-024-51676-0

Verhoef, K., Bilodeau, P. S., nullWamelJ.L.B., V., Kjems, J., Stoltzfus, C. M. & Berkhout, B. (2001). Repair of a Rev-minus HIV-1 mutant by activation of a cryptic splice site. J. Virol., 75, 3495-3500.

Verboom, K., Everaert, C., Bolduc, N., Livak, K. J., Yigit, N., Rombaut, D., Anckaert, J., Lee, S., Venø, M. T., Kjems, J., Speleman, F., Mestdagh, P. & Vandesompele, J. (2019). SMARTer single cell total RNA sequencing. Nucleic Acids Research, 47(16), Article e93. https://doi.org/10.1093/nar/gkz535

Venø, M. T., Bramsen, J. B., Bendixen, C., Panitz, F., Holm, I. E., Öhman, M. & Kjems, J. (2012). Spatio-temporal regulation of ADAR editing during development in porcine neural tissues. RNA Biology, 9(8), 1054-1065. https://doi.org/10.4161/rna.21082

Venø, M. T., Hansen, T. B., Venø, S. T., Clausen, B. H., Grebing, M., Finsen, B., Holm, I. E. & Kjems, J. (2015). Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development. Genome Biology, 16, Article 16:245. https://doi.org/10.1186/s13059-015-0801-3

Venø, M. T., Reschke, C. R., Morris, G., Connolly, N. M. C., Su, J., Yan, Y., Engel, T., Jimenez-Mateos, E. M., Harder, L. M., Pultz, D., Haunsberger, S. J., Pal, A., Heller, J. P., Campbell, A., Langa, E., Brennan, G. P., Conboy, K., Richardson, A., Norwood, B. A. ... Henshall, D. C. (2020). A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy. Proceedings of the National Academy of Sciences (PNAS), 117(27), 15977-15988. https://doi.org/10.1073/pnas.1919313117

Displaying results 1 to 50 out of 443

Revised 08.12.2025

Anne Færch Nielsen