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STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Shi, L., Takahashi, K., Dundee, J., Shahroor-Karni, S., Thiel, S., Jensenius, J. C., Gad, F., Hamblin, M. R., Sastry, K. N. & Ezekowitz, R. A. (2004). Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus. Journal of Experimental Medicine, 199, 1379-1390.
Shi, L., Takahashi, K., Dundee, J., Shahroor-Karni, S., Thiel, S., Jensenius, J. C., Gad, F., Hamblin, M. R., Sastry, K. N. & Ezekowitz, R. A. B. (2004). Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus. Journal of Experimental Medicine, 199(10), 1379-90. https://doi.org/10.1084/jem.20032207
Selander, B., Martensson, U., Weintraub, A., Holmstrom, E., Matsushita, M., Thiel, S., Jensenius, J. C., Truedsson, L. & Sjoholm, A. G. (2006). Mannan-binding lectin activates C3 and the. J. Clin. Invest., 116, 1425-34.
Selander, B., Mårtensson, U., Weintraub, A., Holmström, E., Matsushita, M., Thiel, S., Jensenius, J. C., Truedsson, L. & Sjöholm, A. G. (2006). Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2. Journal of Clinical Investigation, 116(5), 1425-34. https://doi.org/10.1172/JCI25982