Søren Degn

Hagert, C. F., Bohn, A. B., Wittenborn, T. R. & Degn, S. E. (2020). Seeing the Confetti Colors in a New Light Utilizing Flow Cytometry and Imaging Flow Cytometry. Cytometry. Part A, 97(8), 811-823. https://doi.org/10.1002/cyto.a.24032

Fahlquist Hagert, C. & Degn, S. E. (2020). T follicular regulatory cells: Guardians of the germinal centre? Scandinavian Journal of Immunology, 92(4), [e12942]. https://doi.org/10.1111/sji.12942

van der Poel, C. E., Bajic, G., Macaulay, C. W., van den Broek, T., Ellson, C. D., Bouma, G., Victora, G. D., Degn, S. E. & Carroll, M. C. (2019). Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB. Cell Reports, 29(9), 2745-2755.e4. https://doi.org/10.1016/j.celrep.2019.10.086

Wittenborn, T. R., Hagert, C. & Degn, S. E. (2019). Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity. Journal of visualized experiments : JoVE, (146), [e59397]. https://doi.org/10.3791/59397

Degn, S. E., Alicot, E. & Carroll, M. C. (2018). B cell tolerance to epidermal ribonuclear-associated neo-autoantigen in vivo. Clinical and Experimental Immunology, 191(2), 151-165. https://doi.org/10.1111/cei.13066

Firl, D. J., Degn, S. E., Padera, T. & Carroll, M. C. (2018). Capturing change in clonal composition amongst single mouse germinal centers. eLife, 7, [e33051]. https://doi.org/10.7554/eLife.33051

Psianou, K., Panagoulias, I., Papanastasiou, A. D., de Lastic, A-L., Rodi, M., Spantidea, P. I., Degn, S. E., Georgiou, P. & Mouzaki, A. (2018). Clinical and immunological parameters of Sjögren's syndrome. Autoimmunity Reviews, 17(10), 1053-1064. https://doi.org/10.1016/j.autrev.2018.05.005

Degn, S. E., van der Poel, C. E., Firl, D. J., Ayoglu, B., Al Qureshah, F. A., Bajic, G., Mesin, L., Reynaud, C-A., Weill, J-C., Utz, P. J., Victora, G. D. & Carroll, M. C. (2017). Clonal Evolution of Autoreactive Germinal Centers. Cell, 170(5), 913-926. https://doi.org/10.1016/j.cell.2017.07.026

Mortensen, S. A., Skov, L. L., Kjaer-Sorensen, K., Hansen, A. G., Hansen, S., Dagnæs-Hansen, F., Jensenius, J. C., Oxvig, C., Thiel, S. & Degn, S. E. (2017). Endogenous Natural Complement Inhibitor Regulates Cardiac Development. Journal of Immunology, 198(8), 3118-3126. https://doi.org/10.4049/jimmunol.1601958

Degn, S. E., van der Poel, C. E. & Carroll, M. C. (2017). Targeting autoreactive germinal centers to curb autoimmunity. OncoTarget, 8(53), 90624. https://doi.org/10.18632/oncotarget.21701

Bajic, G., Degn, S. E., Thiel, S. & Andersen, G. R. (2015). Complement activation, regulation, and molecular basis for complement-related diseases. E M B O Journal, 34(22), 2735-2757. https://doi.org/10.15252/embj.201591881

Degn, S. E., Kjaer, T. R., Kidmose, R. T., Jensen, L., Hansen, A. G., Tekin, M., Jensenius, J. C., Andersen, G. R. & Thiel, S. (2014). Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes. Proceedings of the National Academy of Sciences of the United States of America, 111(37), 13445-13450. https://doi.org/10.1073/pnas.1406849111

Degn, S. E., Jensenius, J. C. & Thiel, S. (2014). The pro-factor D cleaving activity of MASP-1/-3 is not required for alternative pathway function. Journal of Immunology, 192(12), 5447-8. https://doi.org/10.4049/jimmunol.1400777

Degn, S. E., Jensen, L., Olszowski, T., Jensenius, J. C. & Thiel, S. (2013). Co-complexes of MASP-1 and MASP-2 associated with the soluble pattern-recognition molecules drive lectin pathway activation in a manner inhibitable by MAp44. Journal of Immunology, 191(3), 1334-45. https://doi.org/10.4049/jimmunol.1300780

Chatterjee, P., Agyemang, A. F., Alimzhanov, M. B., Degn, S. E., Tsiftsoglou, S. A., Alicot, E., Jones, S. A., Ma, M. & Carroll, M. C. (2013). Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner. European Journal of Immunology, 43(9), 2441-50. https://doi.org/10.1002/eji.201343412

Degn, S. E. & Thiel, S. (2013). Humoral pattern recognition and the complement system. Scandinavian Journal of Immunology, 78(2), 181-93. https://doi.org/10.1111/sji.12070

Brinkmann, C. R., Jensen, L., Dagnaes-Hansen, F., Holm, I. E., Endo, Y., Fujita, T., Thiel, S., Jensenius, J. C. & Degn, S. E. (2013). Mitochondria and the lectin pathway of complement. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.M112.430249

Degn, S. E., Thiel, S. & Jensenius, J. C. (2013). Recombinant expression of the autocatalytic complement protease MASP-1 is crucially dependent on co-expression with its inhibitor, C1 inhibitor. Protein Expression and Purification, 88(2), 173-182. https://doi.org/10.1016/j.pep.2013.01.002

Degn, S. E., Jensenius, J. C. & Thiel, S. (2013). Response to comment on "Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function". Journal of Immunology, 190(6), 2477-8. https://doi.org/10.4049/jimmunol.1390003

Degn, S. E., Jensen, L., Hansen, A. G., Duman, D., Tekin, M., Jensenius, J. C. & Thiel, S. (2012). Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function. Journal of Immunology, 189(8), 3957-69. https://doi.org/10.4049/jimmunol.1201736

Thiel, S., Jensen, L., Degn, S. E., Nielsen, H. J., Gál, P., Dobó, J. & Jensenius, J. C. (2012). Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components. Clinical and Experimental Immunology. Supplement, 169(1), 38-48. https://doi.org/10.1111/j.1365-2249.2012.04584.x

Degn, S. E., Andersen, S. H., Jensen, L., Thiel, S. & Jensenius, J. C. (2011). Assay interference caused by antibodies reacting with rat kappa light-chain in human sera. Journal of Immunological Methods, 372(1-2), 204-8. https://doi.org/10.1016/j.jim.2011.06.030

Degn, S. E., Jensenius, J. C. & Thiel, S. (2011). Disease-causing mutations in genes of the complement system. American Journal of Human Genetics, 88(6), 689-705. https://doi.org/10.1016/j.ajhg.2011.05.011

Degn, S. E., Thiel, S., Nielsen, O., Hansen, A. G., Steffensen, R. & Jensenius, J. C. (2011). MAp19, the alternative splice product of the MASP2 gene. Journal of Immunological Methods, 373(1-2), 89-101. https://doi.org/10.1016/j.jim.2011.08.006

Gonzalez, S. F., Degn, S. E., Pitcher, L. A., Woodruff, M., Heesters, B. A. & Carroll, M. C. (2011). Trafficking of B cell antigen in lymph nodes. Annual Review of Immunology, 29, 215-233.

Degn, S. E., Jensen, L., Gál, P., Dobó, J., Holmvad, S. H., Jensenius, J. C. & Thiel, S. (2010). Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system. Journal of Immunological Methods, 361(1-2), 37-50. https://doi.org/10.1016/j.jim.2010.07.006

Gonzalez, S. F., Lukacs-Kornek, V., Kuligowski, M. P., Pitcher, L. A., Degn, S. E., Kim, Y-A., Cloninger, M. J., Martinez-Pomares, L., Gordon, S., Turley, S. J. & Carroll, M. C. (2010). Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes. Nature Immunology, 11(5), 427-435.

Gonzalez, S. F., Lukacs-Kornek, V., Kuligowski, M. P., Pitcher, L. A., Degn, S. E., Turley, S. J. & Carroll, M. C. (2010). Complement-dependent transport of antigen into B cell follicles. Journal of Immunology, 185, 2659-2664.

Degn, S. E., Jensenius, J. C. & Bjerre, M. (2010). The lectin pathway and its implications in coagulation, infections and auto-immunity. Current Opinion in Organ Transplantation. https://doi.org/10.1097/MOT.0b013e32834253df

Degn, S. E., Hansen, A., Steffensen, R., Jacobsen, C., Jensenius, J. C. & Thiel, S. (2009). MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation. Journal of Immunology, 183(11), 7371-8. https://doi.org/10.4049/jimmunol.0902388

Thiel, S., Kolev, M., Degn, S. E., Steffensen, R., Hansen, A., Ruseva, M. & Jensenius, J. C. (2009). Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity. Journal of Immunology, 182(5), 2939-47. https://doi.org/10.4049/jimmunol.0802053

Degn, S. E., Thiel, S. & Jensenius, J. C. (2007). New perspectives on mannan-binding lectin-mediated complement activation. Immunobiology, 212, 301-11.