Pedersen, H., Jensen, R. K., Hansen, A. G., Gadeberg, T. A. F., Thiel, S., Laursen, N. S. & Andersen, G. (2020). A C3 specific nanobody that blocks all three activation pathways in the human and murine complement system. The Journal of Biological Chemistry. https://doi.org/10.1074/jbc.RA119.012339

Bernth Jensen, J. M., Petersen, M. S., Ellerman-Eriksen, S., Møller, B. K., Jensenius, J. C., Sørensen, U. B. S. & Thiel, S. (2020). Abundant human anti-Galα3Gal antibodies display broad pathogen reactivity. Scientific Reports, 10(1), [4611]. https://doi.org/10.1038/s41598-020-61632-9

Holt, C. B., Hoffmann-Petersen, I. T., Hansen, T. K., Parving, H-H., Thiel, S., Hovind, P., Tarnow, L., Rossing, P. & Østergaard, J. A. (2020). Association between severe diabetic retinopathy and lectin pathway proteins - an 18-year follow-up study with newly diagnosed type 1 diabetes patients. Immunobiology, [151939]. https://doi.org/10.1016/j.imbio.2020.151939

Świerzko, A. S., Michalski, M., Sokołowska, A., Nowicki, M., Szala-Poździej, A., Eppa, Ł., Mitrus, I., Szmigielska-Kapłon, A., Sobczyk-Kruszelnicka, M., Michalak, K., Gołos, A., Wierzbowska, A., Giebel, S., Jamroziak, K., Kowalski, M. L., Brzezińska, O., Thiel, S., Matsushita, M., Jensenius, J. C. ... Cedzyński, M. (2020). Associations of Ficolins With Hematological Malignancies in Patients Receiving High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantations. Frontiers in Immunology, 10, [3097]. https://doi.org/10.3389/fimmu.2019.03097

Halkjær, L., Troldborg, A., Pedersen, H., Jensen, L., Hansen, A. G., Krarup Hansen, T., Bjerre, M., Østergaard, J. A. & Thiel, S. (2020). Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-level in Plasma Samples from Mice and Humans. Frontiers in Immunology, 11, [774]. https://doi.org/10.3389/fimmu.2020.00774

Holers, V. M., Borodovsky, A., Scheinman, R. I., Ho, N., Ramirez, J. R., Dobó, J., Gál, P., Lindenberger, J., Hansen, A. G., Desai, D., Pihl, R., Thiel, S. & Banda, N. K. (2020). Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D. Frontiers in Immunology, 11, [201]. https://doi.org/10.3389/fimmu.2020.00201

Troldborg, A., Thiel, S., Elbaek, C. M., Hansen, A., Korsholm, T-L., Stengaard-Pedersen, K. & Loft, A. G. (2020). Plasma levels of H- and L-ficolin are increased in axial spondyloarthritis: Improvement of disease identification. Clinical and Experimental Immunology, 199(1), 79-87. https://doi.org/10.1111/cei.13374

Frederiksen, K., Krag, A. E., Larsen, J. B., Kiil, B. J., Thiel, S. & Hvas, A-M. (2020). Remote ischemic preconditioning does not influence lectin pathway protein levels in head and neck cancer patients undergoing surgery. PLOS ONE, 15(4), [e0230411]. https://doi.org/10.1371/journal.pone.0230411

Sokołowska, A., Świerzko, A. S., Szala-Poździej, A., Augustynowicz-Kopeć, E., Kozińska, M., Niemiec, T., Błachnio, M., Borkowska-Tatar, D., Jensenius, J. C., Thiel, S., Dziadek, J. & Cedzyński, M. (2020). Selected factors of the innate immunity in Polish patients suffering from pulmonary tuberculosis. Immunobiology, 151905. https://doi.org/10.1016/j.imbio.2020.151905

Jensen, J. M. B., Møller, B. K., Thiel, S. & Hansen, A. T. (2019). Antibody Dependent Enhancement of Infections after High Dose Chemotherapy. Blood, 134(Supplement 1), 1047. https://doi.org/10.1182/blood-2019-122236

Sandgaard, E., Troldborg, A., Lauridsen, S. V., Gyldenholm, T., Thiel, S. & Hvas, A-M. (2019). Changes in the Lectin Pathway Following Intracerebral or Spontaneous Subarachnoid Hemorrhage. Molecular Neurobiology, 56(1), 78-87. https://doi.org/10.1007/s12035-018-1066-0

Brinck Holt, C., Østergaard, J. A., Thiel, S., Hansen, T. K., Mellbin, L., Sörensson, P. & Bjerre, M. (2019). Circulating lectin pathway proteins do not predict short-term cardiac outcomes after myocardial infarction. Clinical and Experimental Immunology, 198(1), 94-100. https://doi.org/10.1111/cei.13315

Troldborg, A., Voss, A., Hansen, S. W. K., Jensenius, J. C., Stengaard-Pedersen, K. & Thiel, S. (2019). Complement Protein CL-K1 at High Concentrations Protects Against the Development of Lupus Nephritis. Arthritis & Rheumatology, 71(suppl.10), [2895]. https://acrabstracts.org/abstract/complement-protein-cl-k1-at-high-concentrations-protects-against-the-development-of-lupus-nephritis/

Glerup, M., Thiel, S., Rypdal, V., Arnstad, E. D., Ekelund, M., Peltoniemi, S., Aalto, K., Rygg, M., Nielsen, S., Fasth, A., Berntson, L., Nordal, E. & Herlin, T. (2019). Complement lectin pathway protein levels reflect disease activity in juvenile idiopathic arthritis: A longitudinal study of the Nordic JIA cohort. Pediatric Rheumatology , 17(1), [63]. https://doi.org/10.1186/s12969-019-0367-9

Pryds, K., Schmidt, M. R., Bjerre, M., Thiel, S., Refsgaard, J., Bøtker, H. E., Østgård, R. D. & Nielsen, R. R. (2019). Effect of long-term remote ischemic conditioning on inflammation and cardiac remodeling. Scandinavian Cardiovascular Journal, 53(4), 183-191. https://doi.org/10.1080/14017431.2019.1622770

Michalski, M., Pągowska-Klimek, I., Thiel, S., Świerzko, A. S., Hansen, A. G., Jensenius, J. C. & Cedzyński, M. (2019). Factors involved in initiation and regulation of complement lectin pathway influence postoperative outcome after pediatric cardiac surgery involving cardiopulmonary bypass. Scientific Reports, 9, [2930]. https://doi.org/10.1038/s41598-019-39742-w

Troldborg, A., Steffensen, R., Trendelenburg, M., Hauser, T., Winther, K. G., Hansen, A. G., Stengaard-Pedersen, K., Voss, A. & Thiel, S. (2019). Ficolin-3 Deficiency Is Associated with Disease and an Increased Risk of Systemic Lupus Erythematosus. Journal of Clinical Immunology, 39(4), 421-429. https://doi.org/10.1007/s10875-019-00627-2

Larsen, J. B., Andersen, A. S., Hvas, C. L., Thiel, S., Lassen, M. R., Hvas, A-M. & Hansen, A. T. (2019). Lectin pathway proteins of the complement system in normotensive pregnancy and pre-eclampsia. American Journal of Reproductive Immunology Online, 81(4), e13092. [e13092]. https://doi.org/10.1111/aji.13092

Jørgensen, C. M., Jensen, L., Christiansen, M., Bjerre, M., Jensen, J. M. B. & Thiel, S. (2019). Pattern Recognition Molecules of the Lectin Pathway-Screening of Patients with Suspected Immunodeficiency. Journal of Clinical Immunology, 39(7), 668-677. https://doi.org/10.1007/s10875-019-00675-8

Larsen, J. B., Laursen, M. A., Hvas, C. L., Larsen, K. M., Thiel, S. & Hvas, A. M. (2019). Reduced Mannose-Binding Lectin-Associated Serine Protease (MASP)-1 is Associated with Disturbed Coagulation in Septic Shock. Thrombosis and Haemostasis, 119(6), 952-961. https://doi.org/10.1055/s-0039-1685140

Pedersen, D. V., Gadeberg, T. A. F., Thomas, C., Joram, N., Jensen, R. K., Mazarakis, S. M. M., Revel, M., El Sissy, C., Petersen, S. V., Lindorff-Larsen, K., Thiel, S., Laursen, N. S., Fremeaux-Bacchi, V. & Andersen, G. R. (2019). Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Frontiers in Immunology, 10, [2007]. https://doi.org/10.3389/fimmu.2019.02007

Bro-Jeppesen, J., Jeppesen, A. N., Haugaard, S., Troldborg, A., Hassager, C., Kjaergaard, J., Kirkegaard, H., Wanscher, M., Hvas, A-M. & Thiel, S. (2019). The complement lectin pathway protein MAp19 and out-of-hospital cardiac arrest: Insights from two randomized clinical trials. European Heart Journal: Acute Cardiovascular Care. https://doi.org/10.1177/2048872619870031

Jensen, R. K., Pihl, R., Gadeberg, T. A. F., Jensen, J. K., Andersen, K. R., Thiel, S., Laursen, N. S. & Andersen, G. R. (2018). A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement. Journal of Biological Chemistry, 293(17), 6269-6281. https://doi.org/10.1074/jbc.RA117.001179

Yatime, L., Merle, N. S., Hansen, A. G., Friis, N. A., Østergaard, J. A., Bjerre, M., Roumenina, L. T., Thiel, S., Kristensen, P. & Andersen, G. R. (2018). A single-domain antibody targeting complement component c5 acts as a selective inhibitor of the terminal pathway of the complement system and thus functionally mimicks the c-terminal domain of the staphylococcus aureusSSL7 protein. Frontiers in Immunology, 9, [2822]. https://doi.org/10.3389/fimmu.2018.02822

Tizzot, M. R., Lidani, K. C. F., Andrade, F. A., Mendes, H. W., Beltrame, M. H., Reiche, E., Thiel, S., Jensenius, J. C. & de Messias-Reason, I. J. (2018). Ficolin-1 and Ficolin-3 Plasma Levels Are Altered in HIV and HIV/HCV Coinfected Patients From Southern Brazil. Frontiers in Immunology, 9, 2292. [2292]. https://doi.org/10.3389/fimmu.2018.02292

Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J. ... Andersen, V. (2018). Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine. BMJ Open, 8(2), [e018166]. https://doi.org/10.1136/bmjopen-2017-018166

Maestri, C. A., Nisihara, R., Mendes, H. W., Jensenius, J., Thiel, S., Messias-Reason, I. & de Carvalho, N. S. (2018). MASP-1 and MASP-2 Serum Levels Are Associated With Worse Prognostic in Cervical Cancer Progression. Frontiers in Immunology, 9, [2742]. https://doi.org/10.3389/fimmu.2018.02742

Mortensen, S. A., Sander, B., Jensen, R. K., Pedersen, J. S., Golas, M. M., Thiel, S. & Andersen, G. R. (2018). Models of the complement C1 complex. Proceedings of the National Academy of Sciences of the United States of America, 115(17), [E3866]. https://doi.org/10.1073/pnas.1803577115

Medjeral-Thomas, N. R., Troldborg, A., Constantinou, N., Lomax-Browne, H. J., Hansen, A. G., Willicombe, M., Pusey, C. D., Cook, H. T., Thiel, S. & Pickering, M. C. (2018). Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin-Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H-Related Protein-5 (FHR5) Deposition. Kidney International, 3(2), 426-438. https://doi.org/10.1016/j.ekir.2017.11.015

Banda, N. K., Desai, D., Scheinman, R. I., Pihl, R., Sekine, H., Fujita, T., Sharma, V., Hansen, A. G., Garred, P., Thiel, S., Borodovsky, A. & Holers, V. M. (2018). Targeting of Liver Mannan-Binding Lectin-Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis. ImmunoHorizons, 2(8), 274-295. https://doi.org/10.4049/immunohorizons.1800053

Troldborg, A., Jensen, L., Deleuran, B., Stengaard-Pedersen, K., Thiel, S. & Jensenius, J. C. (2018). The C3dg Fragment of Complement Is Superior to Conventional C3 as a Diagnostic Biomarker in Systemic Lupus Erythematosus. Frontiers in Immunology, 9, 581. [581]. https://doi.org/10.3389/fimmu.2018.00581

Troldborg, A., Thiel, S., Trendelenburg, M., Friebus-Kardash, J., Nehring, J., Steffensen, R., Hansen, S. W. K., Laska, M. J., Deleuran, B., Jensenius, J. C., Voss, A. & Stengaard-Pedersen, K. (2018). The Lectin Pathway of Complement Activation in Patients with Systemic Lupus Erythematosus. Journal of Rheumatology, 45(8), 1136-1144. https://doi.org/10.3899/jrheum.171033

Świerzko, A. S., Michalski, M., Sokołowska, A., Nowicki, M., Eppa, Ł., Szala-Poździej, A., Mitrus, I., Szmigielska-Kapłon, A., Sobczyk-Kruszelnicka, M., Michalak, K., Gołos, A., Wierzbowska, A., Giebel, S., Jamroziak, K., Kowalski, M. L., Brzezińska, O., Thiel, S., Jensenius, J. C., Kasperkiewicz, K. & Cedzyński, M. (2018). The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoietic Stem Cell Transplantations (Auto-HSCT). Frontiers in Immunology, 9, 2153. https://doi.org/10.3389/fimmu.2018.02153

Haugaard, S. F., Jeppesen, A. N., Troldborg, A., Kirkegaard, H., Thiel, S. & Hvas, A-M. (2018). The complement lectin pathway after cardiac arrest. Scandinavian Journal of Immunology, 88(2), e12680. [12680]. https://doi.org/10.1111/sji.12680

Larsen, J. B., Troldborg, A., Christensen, T. D., Hvas, C. L., Thiel, S. & Hvas, A-M. (2018). The lectin pathway and coagulation in lung cancer patients undergoing lobectomy - A randomised controlled trial. Thrombosis Research, 163, 92-99. https://doi.org/10.1016/j.thromres.2018.01.042

Andersen, V., Holmskov, U., Sørensen, S. B., Jawhara, M., Andersen, K. W., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. ... Ellingsen, T. (2017). A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Personalised Medicine. Nutrients, 9(5), [499]. https://doi.org/10.3390/nu9050499

Jensen, R. K., Pihl, R., Laursen, N. S., Thiel, S. & Andersen, G. R. (2017). A novel nanobody inhibitor of the alternative pathway. Molecular Immunology, 89, 198. https://doi.org/10.1016/j.molimm.2017.06.207

Pihl, R., Jensen, L., Hansen, A. G., Thøgersen, I. B., Andres, S., Dagnæs-Hansen, F., Oexle, K., Enghild, J. J. & Thiel, S. (2017). Analysis of Factor D Isoforms in Malpuech-Michels-Mingarelli-Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement. Journal of Immunology, 199(6), 2158-2170. https://doi.org/10.4049/jimmunol.1700518

Smedbråten, J., Sagedal, S., Åsberg, A., Hartmann, A., Rollag, H., Mjøen, G., Fagerland, M. W., Hansen, S. W. K., Mollnes, T. E. & Thiel, S. (2017). Collectin Liver 1 and Collectin Kidney 1 of the Lectin Complement Pathway Are Associated With Mortality After Kidney Transplantation. American Journal of Transplantation (Online), 17(1), 265-271. https://doi.org/10.1111/ajt.13933

White, M. R., Tripathi, S., Verma, A., Kingma, P., Takahashi, K., Jensenius, J., Thiel, S., Wang, G., Crouch, E. C. & Hartshorn, K. L. (2017). Collectins, H-ficolin and LL-37 reduce influence viral replication in human monocytes and modulate virus-induced cytokine production. Innate Immunity, 23(1), 77-88. https://doi.org/10.1177/1753425916678470

Axelgaard, E., Østergaard, J. A., Thiel, S. & Hansen, T. K. (2017). Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin. Journal of Diabetes Research, Volume 2017, [6368780]. https://www.hindawi.com/journals/jdr/2017/6368780/

Dørflinger, G. H., Holt, C. B., Thiel, S., Østergaard, J. A. & Hansen, T. K. (2017). Effect of Optimization of Glycaemic Control on Mannan-Binding Lectin in Type 1 Diabetes. Journal of Diabetes Research, 2017, [1249729]. https://doi.org/10.1155/2017/1249729

Mortensen, S. A., Skov, L. L., Kjaer-Sorensen, K., Hansen, A. G., Hansen, S., Dagnæs-Hansen, F., Jensenius, J. C., Oxvig, C., Thiel, S. & Degn, S. E. (2017). Endogenous Natural Complement Inhibitor Regulates Cardiac Development. Journal of Immunology, 198(8), 3118-3126. https://doi.org/10.4049/jimmunol.1601958

Oroszlán, G., Dani, R., Szilágyi, A., Závodszky, P., Thiel, S., Gál, P. & Dobó, J. (2017). Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism. Frontiers in Immunology, 8, 1821. https://doi.org/10.3389/fimmu.2017.01821

Llull, L., Thiel, S., Amaro, S., Cervera, Á., Planas, A. M. & Chamorro, Á. (2017). Ficolin-1 Levels in Patients Developing Vasospasm and Cerebral Ischemia After Spontaneous Subarachnoid Hemorrhage. Molecular Neurobiology, 54(8), 6572-6580. https://doi.org/10.1007/s12035-016-0180-0

Pedersen, D. V., Roumenina, L. T., Jensen, R. K., Gadeberg, T. A., Marinozzi, C., Picard, C., Rybkine, T., Thiel, S., Sørensen, U. B., Stover, C., Fremeaux-Bacchi, V. & Andersen, G. R. (2017). Functional and structural insight into properdin control of complement alternative pathway amplification. E M B O Journal, 36(8). https://doi.org/10.15252/embj.201696173

Axelgaard, E., Østergaard, J. A., Haxha, S., Thiel, S. & Hansen, T. K. (2017). Global Autorecognition and Activation of Complement by Mannan-Binding Lectin in a Mouse Model of Type 1 Diabetes. Mediators of Inflammation, 2017, [9403754]. https://doi.org/10.1155/2017/9403754

Ostergaard, J. A., Thiel, S., Hoffmann-Petersen, I. T., Hovind, P., Parving, H-H., Tarnow, L., Rossing, P. & Hansen, T. K. (2017). Incident microalbuminuria and complement factor mannan-binding lectin-associated protein 19 in people with newly diagnosed type 1 diabetes. Diabetes/Metabolism Research and Reviews, 33(5), [e2895 ]. https://doi.org/10.1002/dmrr.2895