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Elena Ferapontova


Keywords

  • Bioelectronics
  • Antifouling Surfaces
  • Electrocatalysis
  • Bioelectrocatalysis
  • Electroenzymatic Biotransformation
  • Biofuel Cells
  • Bioelectronic Sensing
  • Long-Range Electron Transfer
  • Biomedical Diagnostic Devices
  • Environmental Monitoring Sensors

Head of Electrochemical Biosensors and Bioelectrocatalysis group

Associate Professor Elena E. Ferapontova
PhD in Electrochemistry, Kinetics and Catalysis

Biosensors, Bioelectronics, and Bioelectricity

Our research is focused on electrical and electrocatalytic properties of nucleic acids and enzymes, which we use to develop advanced nanotechnologies for clinical and point-of-care diagnostics, food and environmental biosensors, and novel bioenergy and bioelectronic materials.

The group develops DNA nanotechnologies that exploit electron transport properties of nucleic acids underlying the operation of molecular bioelectronics devices and electrochemical biosensors for cancer biomarkers, neurotransmitters in brain models, and environmental toxicity screening.

Another research direction covers the adaptation of biotechnologically and scientifically challenging enzymatic systems for electrode functioning. The goal is to achieve the most efficient electrochemical wiring of proteins and their bioelectrocatalysis, which can be used in electrochemical biosensors for clinically and industrially important analytes and for sustainable production of electricity in hybrid bio(photo)voltaic devices.

One of our current projects is NUMEN, which focuses on the development of ultrasensitive biosensor nanotechnologies for the analysis of pathogenic microorganisms in air and water, with several industrial collaborations involved such as sensor-producing Unisense, pump-producing Grundfos, and air-analyzer producer TSI Inc. 

Recent publications

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Campbell, C. J., Mountford, C. P., Stoquert, H. C., Buck, A. H., Dickinson, P., Ferapontova, E., Terry, J. G., Beattie, J. S., Walton, A. J., Crain, J., Ghazal, P. & Mount, A. R. (2009). A DNA nanoswitch incorporating the fluorescent base analogue 2-aminopurine detects single nucleotide mismatches in unlabelled targets. Analyst, 134(9), 1873-1879. https://doi.org/10.1039/B900325H, https://doi.org/10.1039/b900325h
Ferapontova, E. (2009). Application of DNA and RNA Beacons in Electroanalysis: What are Limits for Sensitivity and Selectivity?. Abstract from SMCBS'2009: Surface Modification for Chemical and Biochemical Sensing. 4th International Workshop, Cracow, Poland.
Shipovskov, S. & Ferapontova, E. (2009). Biocatalysis of Theophylline Oxidation by Microbial Theophylline Oxidase inthe Presence of Non-Physiological Electron Acceptors. Abstract from VIII Internation Conference "Mechanisms of Catalytic Reactions", Novosibirsk, Russian Federation.
Ferapontova, E. (2009). DNA Nanotechnologies for Selective and Sensitive Electrochemical Sensing. Abstract from From Nanoscience to Biotechnology, København, Denmark.