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Post docs Line D. F. Nielsen and Malthe Hansen-Bruhn after they received the first price for their 3-minute pitch at the TTRN 7th conference.
Private photo.

2019.05.15 | Awards

HONOUR: Two post docs from the Gothelf Lab wins the TTRN pitch competition

Line D. F. Nielsen and Malthe Hansen-Bruhn attended the Transatlantic Telehealth Research Network's (TTRN)'s 7th conference at DTU and won first price.

2019.05.13 | Press release

PRESS COVERAGE: New efficient way to engineer nanostructures mimicking natural immune response complexes

A recently published article in Angewandte Chemie Int. Ed. is the result of a close collaboration between Novo Nordisk A/S and the Gothelf Lab at Aarhus University.

2019.05.10 | Publication

PAPER: Peptide‐Directed DNA‐Templated Protein Labelling for The Assembly of a Pseudo‐IgM

The results of a collaboration between researchers from the Gothelf Lab and research chemists from Novo Nordisk A/S has been published in Angewandte Chemie. In the article, the authors demonstrate how protein binding peptides direct a DNA-templated reaction to form conjugates with a single DNA label. Pentameric star-like DNA-Rituximab…

2019.05.06 | Publication

PAPER: Considerations on Probe Design for Affinity Guided Protein Conjugation

Researchers from the Gothelf lab has recently published a mini review in ChemBioChem on how to design probes for affinity guided protein conjugation, a labelling method based on non-covalent binding interaction between the protein of interest and the probe. This mini review presents the latest progress in the field of affinity…

2019.03.18 | Publication

PAPER: Intracellular bacteria engage a STRING-TBK1-MVB12b pathway to enable paracrine cGAS-STRING signaling

Researchers from the Gothelf lab has recently co-authored an article published in Nature Microbiology. The article reports how the bacterium Listeria monocytogenes' DNA is used to stimulate the cGAS-STRING singling and thereby impairing an antibacterial defence. Read the full article Intracellular bacteria engage a…

2019.02.15 | Publication

PAPER: Imidazole Carbamate Probes for Affinity Guided Azide-Transfer to Metal-Binding Proteins

Researchers from the Gothelf lab has recently published an article on a new method for affinity guided labelling og metal-binding proteins in the journal Organic and Biomolecular Chemistry. To read the article "Imidazole Carbamate Probes for Affinity Guided Azide-Transfer to Metal-Binding Proteins", please visit the journal website.

2019.02.12 | Publication

PAPER: Chemistries for DNA Nanotechnology

Postdoc Mikael Madsen and Professor Kurt Gothelf has very recently published a comprehensive review on chemistries for DNA nanotechnology. The review is published in the journal Chemical reviews and includes topics such as Synthesis of Modified Oligonucleotides, Nucleic Acid analogues, and Reactions on DNA Nanostructures. Visit the journal…

2019.02.06 | Publication

PAPER: Nucleic Acids as a Nature‐Inspired Scaffold for Macromolecular Prodrugs of Nucleoside Analogues

Assistant Professor Alexander Zelikin has recently published and article about molecular prodrugs in the journal Advanced Science. Researchers from the Gothelf Lab has contributed to this study, where nucleic acids are used as scaffold for assembly of macromolecular prodrugs. Please visit the journal website to read the full article Nucleic…

2019.01.30 | Publication

PAPER: Quantitative Detection of Digoxin in Plasma Using Small‐Molecule Immunoassay in a Recyclable Gravity‐Driven Microfluidic Chip

Researchers from the Gothelf lab have recently published an article in Advanced Science about the development a microfluidic chip system that affords precise quantification of the small molecule digoxin. The presented assay is relevant for a potential development of a point-of-care diagnostic device. To read the full article, please visit the…

2019.01.04 | Publication

PAPER: Selective delivery of doxorubicin to EGFR+ cancer cells by Cetuximab-DNA conjugates

Delivery of the anticancer drug Cetuximab to EGFR+ cancer cells has recently been reported in ChemBioChem.

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