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Publications 2019


Peptide-Directed DNA-Templated Protein Labelling for The Assembly of a Pseudo-IgM Nielsen, T. B.; Thomsen, R. P.; Mortensen, M. R.; Kjems, J.; Nielsen, P. F.; Nielsen, T. E.; Kodal, A. L. B.; Clo, E.; Gothelf, K. V. Angew. Chem. 2019, https://doi.org/10.1002/anie.201903134


Considerations on Probe Design for Affinity Guided Protein Conjugation Mortensen, M. R.; Skovsgaard, M. B.; Gothelf, K. V. ChemBioChem 2019, doi.org/10.1002/cbic.201900157


Intracellular Bacteria Engage a STRING-TBK1-MVB12b Pathway to Enable Paracrine cGAS-STRING Signaling Nandakumar, R.; Tschismarov, R.; Meissner, F.; Prabakaran, T.; Farahani, E.; Zhang, B.; Assil, S.; Marin, A.; Bertrams, W.; Holm, C. K.; Ablasser, A.; Klause, T.; Thomasen, M. K.; Schmeck, B.M Howard, K. A.; Henry, T.; Gothelf, K. V.; Decker, T.; Paludan, S. R. Nat. Microbiol.  2019, 4, 701-713, https://doi.org/10.1038/s41564-019-0367-z


Affinity-Guided Conjugation to Antibodies for use in Positron Emission Tomography Skovsgaard, M. B.; Jeppesen, T. E.; Mortensen, M. R.; Nielsen, C. H.; Madsen, J.; Kjær, A.; Gothelf, K. V. Bioconjugate Chem. 201930, 881-887, https://doi.org/10.1021/acs.bioconjchem.9b00013


Chemistries for DNA Nanotechnology Madsen, M; Gothelf, K.V. Chem. Rev. 2019Epub ahead of print. https://doi.org/10.1021/acs.chemrev.8b00570


Nucleic Acids as a Nature-Inspired Scaffold for Macromolecular Prodrugs of Nucleoside   Analogues Krüger, F.; Kumar, V.; Monge, P.; Conzelmann, C.; Smith, N.; Gothelf, K. V.; Tolstrup, M.; Münch, J.; Zelikin, A. N. Adv. Sci. 20196, 1802095, https://doi.org/10.1002/advs.201802095


Imidazole Carbamate Probes for Affinity Guided Azide-Transfer to Metal-Binding Protein Mortensen, M. R.; Nielsen, N. L.; Palmfeldt, J.; Gothelf K. V. Org Biomol Chem201917, 1379-1383, doi.org/10.1039/c8ob03017k


Amperometic Microsensor for Measurement of Gaseous and Dissolved CO2 Revsbech, N. P.; Garcia-Robledo, E.; Sveegaard, S.; Andersen, M. H.; Gothelf, K. V.; Larsen, L. H. Sensors and amp; Actuators: B2019238,349-354. doi.org/10.1016/j.snb.2018.12.038


Quantitative Detection of Digoxin in Plasma Using Small-Molecule Immunoassay in a Recyclable Gravity-Driven Microfluidic Chip Li, H.; Sørensen; J. V.; Gothelf, K.V. Adv. Sci.20196, 1802051. https://doi.org/10.1002/advs.201802051


Selective Delivery of Doxorubicin to EGFR+ Cancer Cells by CetuximabDNA Conjugates Liu, T.; Song, P.; Märcher, A.; Kjems, J.; Yang, C.; Gothelf, K. V. ChemBioChem2019, 20, 1014-1018, https://doi.org/10.1002/cbic.201800685

Publications 2018


Dimethyl Fumarate is an Allosteric Covalent Inhibitor of the p90 Ribosomal S6 Kinases Andersen, J. L.; Gesser B.; Funder, E. D.; Nielsen, C. J. F.; Gotfred-Rasmussen, H.; Toth, R.;   Gothelf, K. V.; Arthur, J. S. C.; Iversen, L.; Nissen, P. Nature Comm20189, 4344. https://doi.org/10.1038/s41467-018-06787-w.1038/s41467-018-06787-w


Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins Mortensen, M. R.; Skovsgaard, M.; Okholm, A. H.; Scavenius, C.; Dupont, D. M.; Rosen, C. B.; Enghild, J. J.; Kjems, J.; Gothelf, K. V. Bioconjugate Chem. 201829, 3016-3025. https://doi.org/10.1021/acs.bioconjchem.8b00424


Rapid Detection of Drugs in Human Plasma using a Small Molecule-Linked Hybridisation Chain Reaction Hansen-Bruhn, M.; Nielsen, L. D. F.; Gothelf, K. V. ACS Sens.20183, 1706-1711. https://doi.org/10.1021/acssensors.8b00439


Controlled Aggregation of DNA Functionalized Poly(Phenylene-Vinylene) Gudnason, D.; Madsen, M.; Krissanaprasit, A.; Gothelf, K. V.; Birkedal, V. Chem. Comm. (Camb.). 2018, 545534-5537. doi.org/10.1039/c8cc00943k


A DNA-Based Assay for Digoxin Detection Kjelstrup, M. V.; Nielsen, L. D. F.; Hansen-Bruhn, M.; Gothelf, K. V. Biosensors 20188, 19-30. https://doi.org/10.3390/bios8010019


Gene Assembly via One-Pot Chemical Ligation of DNA Promoted by DNA Nanostructures Manuguerra, I.; Croce, S.; El-Sagheer, A. H.; Krissanaprasit, A.; Brown, T.; Gothelf, K. V.; Manetto, A. Chem. Comm201854, 4529-4532. doi.org/10.1039/c8cc00738a 


Plasmonic Nanostructures Through DNA-Assisted Lithography Shen B.; Linko, V.; Tapio, K.; Pikker, S.; Lemma, T.; Gopinath, A.; Gothelf, K. V.; Kostiainen, M. A.; Toppari, J. J. Sci. Adv. 20184, eaap8978. doi.org/10.1126/sciadv.aap8978


Active Intracellular Delivery of Cas9-sgRNA Complex Using Ultrasound-Propelled Nanomotors Hansen-Bruhn, M.; Esteban-Fernandez de Avila, B.; Beltrán-Gastélum, M Zhao, J.; Ramírez-Herrera, D. E.; Angsantikul, P.; Gothelf, K. V. G.; Zhang, L.; Wang, J. Angew. Chem. Int. Ed. 201857, 2657-2661. https://doi.org/10.1002/anie.201713082


Development of a Genetically Encodable FRET System Using Fluorescent RNA Aptamers Jepsen, M. D. E.; Sparvath, S. M.; Nielsen, T. B.; Langvad, A. H.; Grossi, G.; Gothelf, K. V.; AndersenE. S. Nature Communications 20189, 18. doi.org/10.1038/s41467-017-02435-x 

Publications 2017


Preparation, Single-Molecule Manipulation, and Energy Transfer Investigation of a Polyfluorene-graft-DNA polymer Madsen, M.; Christensen, R. S.; Krissanaprasit, A.; Bakke, M. R.; Riber, C. F.; Nielsen, K. S.; Zelikin, A. N.; Gothelf, K. V. Chem. Eur. J201723, 10511–10515. https://doi.org/10.1002/chem.201702780


Docking of Antibodies into Cavities in DNA Origami Structures Quyang, X.; De Stefano, M.; Krissanaprasit, A.; Kodal, A. L. B.; Rosen, C. B.; Liu, T.; Helmig, S.; Fan, C.; Gothelf, K. V. Angew. Chem. Int. Ed. 201756, 14423-14427. https://doi.org/10.1002/anie.201706765


AFM Imaging of Hybridization Chain Reaction Mediated Signal Transmission Between two DNA Origami Structures Helmig, S.; Gothelf, K. V. Angew. Chem. Int. Ed. 2017, 56, 13633-13636. https://doi.org/10.1002/anie.201706680


Construction of a Polyhedral DNA 12-Arm Junction for Self-Assembly of Wireframe DNA Lattices Manuguerra, I.; Grossi, G.; Thomsen, R. P.; Lyngsø, J.; Pedersen, J. S.; Kjems, J.; Andersen, E. S.; Gothelf, K. V. ACS Nano201711, 9041-9047. doi.org/10.1021/acsnano. 7b03538


Influence of CH···N Interaction in the Self-Assembly of an Oligo(isoquinolyne-ethynylyne) Molecule with Distinct Conformational States  Nuermaimaiti, A; Ning, Y; Cramer, J. L.; Svane, K. L.; Hammer, B.; Gothelf, K. V.; Linderoth, T. R.  Langmuir 201733, 10782-10791, doi.org/10.1021/acs.langmuir.7b02207


Supramolecular Corrals on Surfaces Resulting from Aromatic Interactions of Nonplanar Triazoles Jethwa, S. J.; Kolsbjerg, E. L.; Vadapoo, S. R.; Cramer, J. L.; Lammich, L.; Gothelf, K. V.; Hammer, B.; Linderoth, T. R. ACS Nano, 2017, 11, 8302-8310, https://doi.org/10.1021/acsnano.7b03484


Site-Selective Conjugation of Native Proteins with DNA Trads, J. B.; Tørring, T.; Gothelf, K. V. Acc. Chem. Res201750, 1367-1374, https://doi.org/10.1021/acs.accounts.6b00618


Steering On-Surface Reactions by a Self-Assembly Approach Chen, Q.; Cramer, J. R.; Liu, J.; Jin, X.; Liao, P.; Shao, X.; Gothelf, K. V.; Wu, K. Angew. Chem. Int. Ed. 201756, 5026-5030, doi.org/10.1002/anie.201700745


Phosphines as Efficient Dioxygen Scavengers in Nitrous Oxide Sensors Sveegaard, S. G.; Nielsen, M.; Andersen, M. H.; Gothelf, K. V. ACS Sens20172, 695-702, doi.org/10.1021/acssensors.7b00152


Revealing the Structural Detail of Individual Polymers Using a Combination of Electrospray Deposition and UHV-STM  Jethwa, S. J.; Madsen, M.; Knudsen, J. B.; Lammich, L.; Gothelf, K. V.; Linderoth, T. R. Chem. Commun. 201753, 1168-1171, doi.org/10.1039/c6cc09167a


Pinning-Down Molecules in Their Self-Assemblies with Multiple Weak Hydrogen Bonds of C—H⋯F and C—H⋯N Jin, X.; Cramer, J. R.; Chen, Q.-W.; Liang, H.-L.; Shang, J.; Shao, X.; Chen, W.; Xu, G.-Q.; Gothelf, K. V.; Wu, K. Chin. Chem. Lett. 201728, 525-530, doi.org/10.1016/j.cclet.2016.11.007

Publications 2016


Selection of Conformational States in Surface Self-Assembly for a Molecule with Eight Possible Pairs of Surface Enantiomers Nuermaimaiti, A.; S-Falk, V.; Cramer, J. L.; Svane, K. L.; Hammer, B.; Gothelf, K. V.; Linderoth, T. R. Chem. Commun. 2016, 52, 14023-14026, doi.org/10.1039/C6CC06876F


DNA-Templated Introduction of an Aldehyde Handle in Proteins Kodal, A. L.; Rosen, C. B.; Mortensen, M. R.; Tørring, T.; Gothelf, K.V. ChemBioChem201617, 1338-1342, doi.org/10.1002/cbic.201600254



Enzyme-Free Colorimetric Detection Systems Based on the DNA Strand Displacement Competition Reaction Zhang, Z.; Birkedal, V.; Gothelf, K. V. New J. Phys. 201618, 055002, doi.org/10.1088/1367-2630/18/5/055002


Protein Patterning by DNA Origami Framework Aslan, H; Krissanaprasit, A; Besenbacher, F; Gothelf, K. V.; Dong, M. Nanoscale 201633, 15233-15240, doi.org/10.1039/C6NR03199D


Intracellular Delivery of a Planar DNA Origami Structure by the Transferrin-Receptor Internalization Pathway Schaffert, D. H.; Okholm, A. H.; Sørensen, R. S.; Nielsen, J. S.; Tørring, T.; Rosen, C. B.; Kodal, A. L.; Mortensen, M. R; Gothelf, K. V.; Kjems, J. Small 201612, 2634-2640, https://doi.org/10.1002/smll.201503934


Dynamic Chemistry of Disulfide Terminated Oligonucleotides in Duplexes and double-crossover tiles De Stefano, M; Gothelf, K. V. ChemBioChem 201617, 1122-1126, https://doi.org/10.1002/cbic.201600076 


Synergistic Inhibitory Effect of Peptide-Organic Co-assemblies on Amyloid Aggregation Niu, L.; Liu, L.; Xi, W.; Han, Q.; Li, Q.; Yu, Y.; Huang, Q.; Qu, F.; Xu, M.; Li, Y.; Du, H.; Yang, R.; Cramer, J.; Gothelf, K. V.; Dong, M.; Besenbacher, F.; Zeng, Q.; Wang, C.; Wei, G.; Yang, Y. ACS Nano 201610, 4143-4153, doi.org/10.1021/acsnano.5b07396


Programmed Switching of Single Polymer Conformation on DNA Origami Krissanaprasit, A.; Madsen, M.; Knudsen, J. B.; Gudnason, D. A.; Surareungchai, W.; Birkedal, V.; Gothelf, K. V.; ACS Nano 201610, 2243-50, doi.org/10.1021/acsnano.5b06894


Synthesis and Biophysical Properties of (L)-aTNA Based G-quadruplexes Kumar. V.; Gothelf, K. V. Org. Biomol. Chem201614, 1540-1544, https://doi.org/10.1039/C5OB02525G


Suspending DNA Origami Between Four Gold Nanodots Morales, P.; Wang, L.; Krissanaprasit, A.; Dalmastri, C.; Caruso, M.; Stefano, M. D.; Mosiello, L.; Rapone, B.; Rinaldi, A.; Vespucci, S.; Vinther, J.; Retterer, S.; Gothelf, K. V. Small 201612, 169-173, https://doi.org/10.1002/smll.201501782

Publications 2015


Alignment of Gold Nanoparticle-Decorated DNA Origami Nanotubes Substrate Prepatterning vs. Molecular Combing Teschome, B.; Facsko, S.; Gothelf, K. V.; Keller, A. Langmuir 2015, 31, 12823–12829, https://doi.org/10.1021/acs.langmuir.5b02569


A DNA-Based System for Selecting and Displaying the Combined Result of Two Input Variables Liu, H.; Wang, J.; Song, S.; Fan, C.; Gothelf, K. V. Nature Commun. 2015, 6, 10089, https://doi.org/10.1038/ncomms10089


Routing of Individual Polymers in Designed Patterns Knudsen, J. B.; Liu, L.; Bank Kodal, A. L.; Madsen, M.; Li, Q.; Song, J.; Woehrstein, J. B.; Wickham, S. F.; Strauss, M. T.; Schueder, F.; Vinther, J.; Krissanaprasit, A.; Gudnason, D.; Smith, A. A.; Ogaki, R.; Zelikin, A. N.; Besenbacher, F.; Birkedal, V.; Yin, P.; Shih, W. M.; Jungmann, R.; Dong, M.; Gothelf, K.V. Nature Nanotechnol. 2015, 10, 892-898, https://doi.org/10.1038/nnano.2015.190


Selection of Conformational States in Self-Assembled Surface Structures Formed From an Oligo(Naphthylene-Ethynylene) 3-bit Binary Switch Ning, Y.; Cramer, J. R.; Nuermaimaiti, A.; Svane, K.; Yu, M.; Lægsgaard, E.; Besenbacher, F.; Xue, Q. K.; Ma, X.; Hammer, B.; Gothelf, K. V.; Linderoth, T. R. J. Chem. Phys. 2015142, 101922-101929, doi.org/10.1063/1.4908062


Oxidative Activation of Dihydropyridine Amides to Reactive Acyl Donors  Funder, E. D.; Trads, J. B.; Gothelf, K. V. Org. Biomol. Chem. 201513, 185-198, https://doi.org/10.1039/c4ob01931h   


Highly Stable Triple Helix Formation by Homopyrimidine (l)-Acyclic Threoninol Nucleic Acids With Single Stranded DNA and RNA Kumar V.; Kesavan V.; Gothelf, K. V. Org. Biomol. Chem. 201513, 2366-74, https://doi.org/10.1039/c4ob02328e

Publications 2014


Synthesis, Dynamic Combinatorial Chemistry, and PCR Amplification of 3 '-5 ' and 3 '-6 ' Disulfide-linked Oligonucleotides Hansen, D. J.; Manuguerra, I.; Kjelstrup, M. B.; Gothelf, K. V. Angew. Chem. Int. Ed. 201453, 14415-14418, https://doi.org/10.1002/anie.201405761


Sequence Dependence of Electron-Induced DNA Strand Breakage Revealed by DNA Nanoarrays Keller, A.; Rackwitz, J.; Cauet, E.; Lievin, J.; Korzdorfer, T.; Rotaru, A.; Gothelf, K. V.; Besenbacher, F.; Bald, I. Sci. Rep. 20144, 7391, https://doi.org/10.1038/srep07391


A DNA-Mediated Homogenous Binding Assay for Proteins and Small Molecules Zhang, Z.; Hejesen, C.; Kjelstrup, M.; Birkedal, V.; Gothelf, K. V. J. Am. Chem. Soc. 2014136, 11115-11120, https://doi.org/10.1021/ja505519b


Template-Directed Covalent Conjugation of DNA to Native Antibodies, Transferrin and Other Metal-Binding Proteins Rosen, C. B.; Kodal, A. L.; Nielsen, J. S.; Schaffert, D. H.; Scavenius, C.; Okholm, A. H.; Voigt, N. V.; Enghild, J. J.; Kjems, J.; Tørring, T.; Gothelf, K. V. Nature Chem. 20146, 804-809, doi.org/10.1038/nchem.2003


Chiral Induction with Chiral Conformational Switches in the Limit of Low "Sergeants to Soldiers" Ratio  Nuermaimaiti, A.; Bombis, C.; Knudsen, M. M.; Cramer, J. R.; Lægsgaard, E.; Besenbacher, F.; Gothelf, K. V.; Linderoth, T. R. ACS Nano20148, 8074-8081, doi.org/10.1021/nn502097h


Transformation of Beta-Sheet Structures of the Amyloid Peptide Induced by Molecular Modulators Niu, L.; Liu, L.; Xu, M.; Cramer, J.; Gothelf, K. V.; Dong, M.; Besenbacher, F.; Zeng, Q. D.; Yang, Y. L.; Wang, C. Chem. Commun. 201450, 8923-8926, doi.org/10.1039/c4cc02748e


Single Molecule FRET Analysis of the 11 Discrete Steps of a DNA Actuator Hildebrandt, L. L.; Preus, S.; Zhang, Z.; Voigt, N. V.; Gothelf, K. V.; Birkedal, V. J. Am. Chem. Soc.2014136, 8957-8962, https://doi.org/10.1021/ja502580t


Synthesis of Homochiral Tris-Indanyl Molecular Rods Kjeldsen, N. D.; Funder, E. D.; Gothelf, K. V. Org. Biomol. Chem201412, 3679-3685, https://doi.org/10.1039/c4ob00011k


Singlet Oxygen in DNA Nanotechnology Tørring, T.; Helmig, S. D.; Ogilby, P. R.; Gothelf. K. V. Acc. Chem. Res201447, 1799-1806, https://doi.org/10.1021/ar500034y


Function and Movement of a DNA Actuator Investigated by Single Molecule Fret Microscopy Hildebrandt, L. L.; Zhang, Z.; Preus, S.; Gothelf, K. V.; Birkedal, V. Biophys. J. 2014106, 226a, doi.org/10.1016/j.bpj.2013.11.1321


Tailoring on-surface supramolecular architectures based on adenine directed self-assembly Tan, Q.; Zhang, C.; Wang, N.; Sun, Q.; Zhu X.; Jacobsen, M. F.; Gothelf, K. V.; Besenbacher, F.; Hu, A.; Xu, W. Chem. Commun. 201450, 356-358, doi.org/10.1039/c3cc46149a

Publications 2013


Efficient Colorimetric and Fluorescent Detection of Fluoride in DMSO-Water Mixtures with Arylaldoximes Rosen, C. B.; Hansen, D. J.; Gothelf, K. V. Org. Biomol. Chem201311, 7916-7922, https://doi.org/10.1039/c3ob41078a


Isothermal Hybridization Kinetics of DNA Assembly of Two-Dimensional DNA Origami Song, J.; Zhang, Z.; Zhang, S.; Liu, L.; Li, Q.; Xie, E. Q.; Gothelf, K. V.; Besenbacher, F.; Dong, M. Small 201317, 2954-2959, doi.org/10.1002/smll.201202861


Self-Assembly of DNA Origami and Single-Stranded Tile Structures at Room Temperature Zhang, Z.; Song, J.; Besenbacher, F.; Dong, M.; Gothelf, K. V. Angew. Chem. Int. Ed. 201352, 9219-9223, doi.org/10.1002/anie.201303611


Electron-Induced Damage of Biotin Studied in the Gas Phase and in the Condensed Phase at a Single-Molecule Level Keller, A.; Kopyra, J.; Gothelf, K. V.; Bald, I. New J. Phys201315, 083045, https://doi.org/10.1088/1367-2630/15/8/083045


Enzymatic Ligation of Large Biomolecules to DNA Sørensen, R. S.; Okholm, A. H.; Schaffert, D.; Kodal, A. L. B.; Gothelf, K. V.; Kjems. J. ACS Nano20137, 8098-8104, doi.org/10.1021/nn403386f


A DNA-Tweezer-Actuated Enzyme Nanoreactor Liu, M.; Fu, J.; Hejesen, C.; Yang, Y.; Woodbury, N. W.; Gothelf, K. V.; Liu, Y.; Yan, H. Nature Commun. 20134, 2127-2132, doi.org/10.1038/ncomms3127


DNA Nanotechnology: A Curiosity or a Promising Technology? Tørring, T; Gothelf, K. V. F100Prime Rep20135, 14, doi.org/10.12703/P5-14


Oligo(naphthylene-ethynylene) Molecular Rods Cramer, J. R.; Ning, Y. X.; Shen, C.; Nuermaimaiti, A.; Besenbacher, F.; Linderoth, T. R.; Gothelf, K. V. Eur. J. Org. Chem. 2013, 2813-2822, doi.org/10.1002/ejoc.201201752


On Electrogenerated Acid-Facilitated Electrografting of Aryltriazenes to Create Well-Defined Aryl-Tethered Films Vinther, J.; Iruthayaraj, J.; Gothelf, K. V.; Pedersen, S. U.; Daasbjerg, K. Langmuir 201329, 5181-5189, doi.org/10.1021/la305081c


On-Surface Azide–Alkyne Cycloaddition on Cu(111): Does It “Click” in Ultrahigh Vacuum?Bebensee, F.; Bombis, C.; Vadapoo, S.-R. Cramer, J. R.; Besenbacher, F.; Gothelf, K. V.; Linderoth, T. R. J. Am. Chem. Soc2013135, 2136-2139, doi.org/10.1021/ja312303a


Novel Self-Assembled Nanoparticles of Testosterone-Modified Glycol Chitosan and Fructose Chistosan for Controlled Release Perez Quinones, J.; Gothelf, K. V.; Kjems, J.; Heras, A.; Schmidt, C.; Peniche, C. J Biomater. Tissue Eng. 20133, 164-172, doi.org/10.1166/jbt.2013.1071


Self-assembled Nanoparticles of Modified-Chitosan Conjugates for the Sustained Release of DL-alpha-tocopherol Perez Quinones, J.; Gothelf, K. V.; Kjems, J.; Yang, C.; Caballero, A. M. H.; Schmidt C.; Covas, C. P. Carbohyd. Polym201392, 856-864, doi.org/10.1016/j.carbpol.2012.10.005


Single-Step Rapid Assembly of DNA Origami Nanostructures for Addressable Nanoscale Bioreactors Fu, Y.; Zeng, D.; Chao, J.; Zhang, Z.; Liu, H.; Li D.; Ma, H.; Huang, Q.; Gothelf, K. V.; Fan, C. J. Am. Chem. Soc. 2013135, 696-702, doi.org/10.1021/ja3076692


N,06-Partially Acetylated Chitosan Nanoparticles Hydrophobically-Modified for Controlled Release of Steroids and Vitamin E Pérez Quinones, J.; Gothelf, K. V.; Kjems. J.; Caballero, A. M. H.; Schmidt, C.; Covas, C. P. Carbohydr. Polym201391, 143-151, doi.org/10.1016/j.carbpol.2012.07.080


A Traceless Aryl-Triazene Linker for DNA-Directed Chemistry Hejesen, C.; Petersen, L. K.; Hansen, N. J. V.; Gothelf. K. V. Org. Biomol. Chem. 201311, 2493-2497, doi.org/10.1039/c3ob27504c


Transfer of a Protein Pattern From Self-Assembled DNA Origami to a Functionalized Substrate Busuttil, K.; Rotaru, A.; Dong, M.; Besenbacher F.; Gothelf, K. V. Chem. Commun. 201349, 1927-1929, doi.org/10.1039/C3CC37408D


RNA Aptamer-Based Electrochemical Biosensor for Selective and Label-Free Analysis of Dopamine Farjami, E.; Campos, R.; Nielsen, J.; Gothelf, K. V.; Kjems, J.; Ferapontova, E. Anal. Chem. 201385, 121-128, doi.org/10.1021/ac302134s


Steering Supramolecular Patters by Nucleobase-Terminated Molecules Shen, C.; Cramer, J. R.; Jacobsen, M. F.; Liu, L.; Zhang, S.; Dong, M.; Gothelf, K. V.; Besenbacher, F. Chem. Commun. 201349, 508-510, doi.org/10.1039/C2CC37522B

Publications 2012


Extended DNA Tile Actuators Kristiansen, M.; Kryger, M. B. L.; Zhang, Z.; Voigt, N. V.; Birkedal,V.; Gothelf, K. V. ChemPlusChem 201277, 636-642, doi.org/10.1002/cplu.201200149


Electrochemical Sandwich Assay for Attomole Analysis of DNA and RNA From Beer Spoilage Bacteria Lactobacillus brevis Shipovskov, S.; Saunders, A. M.; Nielsen, J. S.; Hansen, M. H.; Gothelf, K. V.; Ferapontova, E. E. Biosens. Bioelectron. 201237, 99-106, doi.org/10.1016/j.bios.2012.05.001


Increased Anticoagulant Activity of Thrombin-Binding DNA Aptamers by Nanoscale Organization on DNA Nanostructures Rangnekar, A.; Zhang, A. M.; Li, S. S.; Bompiani, K. M.; Hansen, M. N.; Gothelf, K. V.; Sullenger, B. A.; LaBean, T. H. Nanomed-Nanotechnol20128, 673-681, https://doi.org/10.1016/j.nano.2011.08.011


Direct Visualization of Transient Thermal Response of a DNA Origami Song, J.; Arbona, J-M.; Zhang, Z.; Liu, L.; Xie, E. Q.; Elezgaray, J.; Aime, J-P.; Gothelf, K.V.; Besenbacher, F.; Dong, M. D. J. Am. Chem. Soc. 2012134, 9844-9847, https://doi.org/10.1021/ja3017939   


Self-Assembled Nanoparticles of Glycol Chitosan – Ergocalciferol Succinate conjugate, for controlled release Quinones Pérez, J.; Gothelf , K. V.; Kjems, J.; Caballero, A. M. H.; Scmidt, C.; Covas, C. P. Carbohyd. Polym. 201288, 1373-1377. doi.org/10.1016/j.carbpol.2012.02.039


Probing Electron-Induced Bond Cleavage at the Single-Molecule Level Using DNA Origami Templates  Keller, A.; Bald, I.; Rotaru, A.; Cauët, E.; Gothelf, K. V.; Besenbacher, F. ACS Nano 20126, 4392-4399, doi.org/10.1021/nn3010747


Synthesis of Dopamine and Serotonin Derivatives for Immobilization on a Solid Support Funder, E. D.; Jensen, A. B.; Tørring, T.;  Kodal, A. L. B.; Azcargorta, A. R.; Gothelf, K. V. J. Org. Chem. 201277, 3134–3142, doi.org/10.1021/jo2025477


Multilayer DNA Origami Packed on Hexagonal and Hybrid Lattices Ke, Y.; Voigt, N. V.; Gothelf, K. V.; Shih, W. M. J. Am. Chem. Soc. 2012134, 1770-1774, doi.org/10.1021/ja209719k

Publications 2011


DNA-Programmed Glaser-Eglinton Reactions for the Synthesis of Conjugated Molecular Wires Ravnsbæk, J. B.; Jacobsen, M. F.; Rosen, C. B.; Voigt, N. V.; Gothelf, K. V. Angew. Chem. Int. Ed. 201150, 10851-10854, doi.org/10.1002/anie.201105095


Chiral Induction by Seeding Surface Assemblies of Chiral Switches Masini, F.; Kalashnyk, N.; Knudsen, M. M.; Cramer, J. R.; Lægsgaard, E.; Besenbacher, F.; Gothelf, K. V.; Linderoth, T. R. J. Am. Chem. Soc.2011133, 13910-13913, https://doi.org/10.1021/ja205998c


Control of Self-Assembled 2D Nanostructures by Methylation of Guanine Bald, I.; Wang, Y. G.; Dong, M.; Rosen, C. B.; Ravnsbæk, J. B.; Zhuang, G. L.; Gothelf, K. V.; Wang, J. G.; Besenbacher, F. Small 20117, 939-949, doi.org/10.1002/smll.201002033


Single Molecule Microscopy Methods for the Study of DNA Origami Structures Birkedal, V.; Dong, M.; Golas, M. M.; Sander, B.; Andersen, E. S.; Gothelf, K. V.; Besenbacher, F.; Kjems, J. Microsc. Res. Techniq. 201174, 688-698, doi.org/10.1002/jemt.20962


"Off–On" Electrochemical Hairpin-DNA-Based Genosensor for Cancer Diagnostics Farjami, E.; Clima, L.; Gothelf, K. V.; Ferapontova, E. E. Anal. Chem. 201183, 1594-1602, doi.org/10.1021/ac1032929


Recent Advances in Electrochemical Aptamer-Based Sensors Ferapontova, E. E.; Gothelf, K. V. Curr. Org. Chem. 201115, 498-505, https://doi.org/10.2174/138527211794474483


β-Olefination of 2-Alkynoates Leading to Trisubstituted 1,3-Dienes Jacobsen, M. J.; Funder, E. D.; Cramer, J. R.; Gothelf, K. V. Org. Lett. 201113, 3418-3421, doi.org/10.1021/ol2011677


Site-Specific Chemical Labeling of Long RNA Molecules Jahn, K.; Olsen, E. M.; Nielsen, M. M.; Tørring, T.; MohammadZadegan, R.; Andersen, E. S.; Gothelf, K. V.; Kjems, J. Bioconjugate Chem. 201122, 95-100, doi.org/10.1021/bc100422k


Functional Patterning of DNA Origami by Parallel Enzymatic Modification Jahn, K.; Tørring, T.; Voigt, N. V.; Sørensen, R. S.; Kodal, A. L. B.; Andersen, E. S.; Gothelf, K. V.; Kjems, J. Bioconjugate Chem. 201122, 819-823, doi.org/10.1021/bc2000098


Controlling Chiral Organization of Molecular Rods on Au(111) by Molecular Design Knudsen, M. K.; Kalashnyk, N.; Masini, F.; Cramer, J. R.; Lægsgaard, E.; Besenbacher, F.; Linderoth, T. R.; Gothelf, K. V. J. Am. Chem. Soc. 2011133, 4896-4905, https://doi.org/10.1021/ja110052n


Combining Aryltriazenes and Electrogenerated Acids to Create Well-Defined Aryl-Tethered Films and Patterns on Surfaces Kongsfelt, M.; Vinther, J.; Malmos, K.; Ceccato, M.; Torbensen, K.; Knudsen, C. S.; Gothelf, K. V.; Pedersen, S. U.; Daasbjerg, K. J. Am. Chem. Soc. 2011133, 3788-3791, https://doi.org/10.1021/ja111731d


Design and Construction of Double-Decker Tile as a Route to Three-Dimensional Periodic Assembly of DNA Majumder, U.; Rangnekar, A.; Gothelf, K. V.; Reif, J. H.; LaBean, T. H. J. Am. Chem. Soc. 2011133, 3843-3845, doi.org/10.1021/ja1108886


Development of a Lipase-Based Optical Assay for Detection of DNA Pinijsuwan, S.; Shipovskov, S.; Surareungchai, W.; Ferapontova, E. E.; Gothelf, K. V. Org. Biomol. Chem. 20119, 6352-6356, doi.org/10.1039/c0ob01165g


Design and Synthesis of DNA Four-Helix Bundles Rangnekar, A.; Gothelf, K. V.; LaBean, T. H. Nanotechnology 201122, 235601-235609, https://doi.org/10.1088/0957-4484/22/23/235601


DNA Origami: a Quantum Leap for Self-Assembly of Complex Structures Tørring, T.; Voigt, N. V.; Nangreave, J.; Yan, H.; Gothelf, K. V. Chem. Soc. Rev. 201140, 5636-5646, doi.org/10.1039/c1cs15057j


A DNA Tile Actuator With Eleven Discrete States Zhang, Z.; Olsen, E. M.; Kryger, M.; Voigt, N. V.; Tørring, T.; Gültekin, E.; Nielsen, M.; Mohammad Zadegan, R.; Andersen, E. S.; Nielsen, M. M.; Kjems, J.; Birkedal, V.; Gothelf, K. V. Angew. Chem. Int. Ed. 201150, 3983-3987, doi.org/10.1002/anie.201007642

Publications 2010


A Nucleic Acid Dependent Chemical Photocatalysis in Live Human Cells Arian, D.; Cló, E.; Gothelf, K. V.; Mokhir, A. Chem,. Eur. J. 201016, 288-295, https://doi.org/10.1002/chem.200902377


Steering Organizational and Conformational Surface Chirality by Controlling Molecular Chemical Functionality Bombis, C.; Weigelt, S.; Knudsen, M. M.; Nørgaard, M.; Busse, C.; Lægsgaard, E.; Besenbacher, F.; Gothelf, K. V.; Linderoth, T. R., ACS Nano 20104, 297-311, https://doi.org/10.1021/nn9012803


DNA Interactions with a Methylene Blue Redox Indicator Depend on The DNA Length and are Sequence Specific Farjami, E.; Clima, L.; Gothelf, K. V.; Ferapontova, E. E. Analyst 2010135, 1443-1448, https://doi.org/10.1039/c0an00049c


Electrochemical DNA Sandwich Assay with a Lipase Label for Attomole Detection of DNA Ferapontova, E. E.; Hansen, M. N.; Saunders, A. M.; Shipovskov, S.; Sutherland, D. S.; Gothelf, K. V. Chem. Commun. 201046, 1836-1838, doi.org/10.1039/B924627D


Synthesis and Application of a Triazene–Ferrocene Modifier for Immobilization and Characterization of Oligonucleotides at Electrodes Hansen, M. N.; Farjami, E.; Kristiansen, M.; Clima, L.; Pedersen, S. U.; Daasbjerg, K.; Ferapontova, E. E.; Gothelf, K. V. J. Org. Chem. 201075, 2474-2481, https://doi.org/10.1021/jo9024368


Weave Tile Architecture Construction Strategy for DNA Nanotechnology Hansen, M. N.; Zhang, A. M.; Rangnekar, A.; Bompiani, K. M.; Carter, J. D.; Gothelf, K. V.; LaBean, T. H. J. Am. Chem. Soc. 2010132, 14481-14486, doi.org/10.1021/ja104456p


Single Molecule Atomic Force Microscopy Studies of Photosensitized Singlet Oxygen Behavior on a DNA Origami Template Helmig, S.; Rotaru, A.; Arian, D.; Kovbasyuk, L.; Arnbjerg, J.; Ogilby, P. R.; Kjems, J.; Mokhir, A.; Besenbacher, F.; Gothelf, K. V. ACS Nano 20104, 7475-7480, https://doi.org/10.1021/nn102701f


Small Molecule Induced Control in Duplex and Triplex DNA-Directed Chemical Reactions Jacobsen, M. F.; Ravnsbæk, J. B.; Gothelf, K. V. Org. Biomol. Chem. 20108, 50-52, https://doi.org/10.1039/B919387A


DNA-Templated Covalent Coupling of G4 PAMAM Dendrimers Liu, H.; Tørring, T.; Dong, M.; Rosen, C. B.; Besenbacher, F.; Gothelf, K. V. J. Am. Chem. Soc. 2010132, 18054-18056, doi.org/10.1021/ja109677n


Selective dsDNA-Templated Formation of Copper Nanoparticles in Solution Rotaru, A.; Dutta, S.; Jentzsch, E.; Gothelf, K. V.; Mokhir, A. Angew. Chem. Int. Ed. 201049, 5665-5667, doi.org/10.1002/anie.200907256


A Novel Secondary DNA Binding Site in Human Topoisomerase I Unravelled by Using a 2D DNA Origami Platform Subramani, R.; Juul, S.; Rotaru, A.; Andersen, F. F.; Gothelf, K. V.; Mamdouh, W.; Besenbacher, F.; Dong, M.; Knudsen, B. R. ACS Nano 20104, 5969-5977, https://doi.org/10.1021/nn101662a


Reversible pH-Regulated Control of Photosensitized Singlet Oxygen Production Using a DNA i-motif Tørring, T.; Toftegaard, R.; Arnbjerg, J.; Ogilby, P. R.; Gothelf, K. V. Angew. Chem. Int. Ed. 201049, 7923-7925, doi.org/10.1002/anie.201003612


Single-Molecule Chemical Reactions on DNA Origami Voigt, N. V.; Tørring, T.; Rotaru, A.; Jacobsen, M. F.; Ravnsbæk, J. B.; Subramani, R.; Mamdouh, W.; Kjems, J.; Mokhir, A.; Besenbacher, F.; Gothelf, K. V. Nature Nanotech. 20105, 200-203, doi.org/10.1038/nnano.2010.5


Supramolecular Porous Network Formed by Molecular Recognition Between Chemically Modified Nucleobases Guanine and Cytosine Xu, W.; Wang, J-G.; Jacobsen, M. F.; Mura, M.; Yu, M.; Kelly, R. E. A.; Meng, Q-Q..; Lægsgaard, E.; Stensgaard, I.; Linderoth, T. R.; Kjems, J.; Kantorovich, L. N.; Gothelf, K. V.; Besenbacher, F. Angew. Chem. Int. Ed. 201049, 9373-9377, doi.org/10.1002/anie.201003390

Publications 2009


Synthesis of Functional Molecular Rod Oligomers Andersen, C. S.; Gothelf, K. V. Org. Biomol. Chem. 20097, 58-60, doi.org/10.1039/B815099K


Distance Dependent Interhelical Couplings of Organic Rods Incorporated in DNA 4-Helix Bundles Andersen, C. S.; Knudsen, M. M.; Chhabra, R.; Liu, Y.; Yan, H.; Gothelf, K. V. Bioconjugate Chem. 200920, 1538-1546, doi.org/10.1021/bc900078c


Self-Assembly of a Nanoscale DNA box With a Controllable Lid Andersen, E. S.; Dong, M.; Nielsen, M. M.; Jahn, K.; Subramani, R.; Mamdouh, W.; Golas, M. M.; Sander, B.; Stark, H.; Oliveira, C. L. P.; Pedersen, J. S.; Birkedal, V.; Besenbacher, F.; Gothelf, K. V.; Kjems, J. Nature 2009459, 73-76, doi.org/10.1038/nature07971


Optimization of the Electrochemical RNA-Aptamer Based Biosensor for Theophylline by Using a Methylene Blue Redox Label Ferapontova, E. E.; Gothelf, K. V. Electroanalysis200921, 1261-1266, https://doi.org/10.1002/elan.200804558


Effect of Serum on an RNA Aptamer-Based Electrochemical Sensor for Theophylline Ferapontova, E. E.; Gothelf, K. V. Langmuir 200925, 4279-4283, doi.org/10.1021/la804309j


A Yoctoliter-Scale DNA Reactor for Small-Molecule Evolution Hansen, M. H.; Blakskjær, P.; Petersen, L. K.; Hansen, T. H.; Højfeldt, J. W.; Gothelf, K. V.; Hansen, N. J. V. J. Am. Chem. Soc. 2009131, 1322-1327, doi.org/10.1021/ja808558a


Synthesis and Electrochemical Studies of an Anthraquinone-Conjugated Nucleoside and Derived Oligonucleotides Jacobsen, M. F.; Ferapontova, E. E.; Gothelf, K. V. Org. Biomol. Chem. 20097, 905-908, https://doi.org/10.1039/B816820B


Effect of Polymer Cross-Links on Oxygen Diffusion in Glassy PMMA Films Klinger, M.; Tolbod, L. P.; Gothelf, K. V.; Ogilby, P. R. ACS Appl. Mater. Interfaces 20091, 661-667, doi.org/10.1021/am800197j


Self-Assembly of Artificial Nucleobase 1H-Benzimidazole-4,7-dione at the Liquid/Solid Interface Mamdouh, W.; Kelly, R. E. A.; Dong, M.; Jacobsen, M. F.; Ferapontova, E. E.; Kantorovich, L. N.; Gothelf, K. V.; Besenbacher, F. J. Phys. Chem. B 2009113, 8675-8681, https://doi.org/10.1021/jp9029419

Publications 2008


Bridging One Helical Turn in Double-Stranded DNA by Templated Dimerization of Molecular Rods Andersen, C. S.; Yan, H.; Gothelf, K. V. Angew. Chem. Int. Ed. 200847, 5569-5572, https://doi.org/10.1002/anie.200800819


DNA Origami Design of Dolphin-Shaped Structures With Flexible Tails Andersen, E. S.; Dong, M.; Nielsen, M. M.; Jahn, K.; Lind-Thomsen, A.; Mamdouh, W.; Gothelf, K. V.; Besenbacher, F.; Kjems, J. ACS Nano 20082, 1213-1218, https://doi.org/10.1021/nn800215j


Labeling of DNA via Rearrangement of s-2-Aminoethyl Phosphorothioates to n-(2-Mercaptoethyl)Phosphoramidates Chen, M.; Gothelf, K. V. Org. Biomol. Chem.20086, 908-911, doi.org/10.1039/b717664c


An RNA Aptamer-Based Electrochemical Biosensor for Detection of Theophylline in Serum Ferapontova, E. E.; Olsen, E. M.; Gothelf, K. V. J. Am. Chem. Soc. 2008130, 4256-4258, https://doi.org/10.1021/ja711326b


Toward Reliable Gold Nanoparticle Patterning on Self-Assembled DNA Nanoscaffold Sharma, J.; Chhabra, R.; Andersen, C. S.; Gothelf, K. V.; Yan, H.; Liu, Y. J. Am. Chem. Soc. 2008130, 7820-7821, doi.org/10.1021/ja802853r


Molecular Self-Assembly from Building Blocks Synthesized on a Surface in Ultrahigh Vacuum: Kinetic Control and Topo-Chemical Reactions Weigelt, S.; Bombis, C.; Busse, C.; Knudsen, M. M.; Gothelf, K. V.; Lægsgaard, E.; Besenbacher, F.; Linderoth, T. R. ACS Nano 20082, 651-660, doi.org/10.1021/nn7004365


Surface Synthesis of 2D Branched Polymer Nanostructures Weigelt, S.; Busse, C.; Bombis, C.; Knudsen, M. M.; Gothelf, K. V.; Lægsgaard, E.; Besenbacher, F.; Linderoth, T. R. Angew. Chem. 2008120, 4478-4482, https://doi.org/10.1002/anie.200705079

Publications 2007


Chiral Ordering and Conformational Dynamics for a Class of Oligo-Phenylene-Ethynylenes on Au(111) Busse, C.; Weigelt, S.; Petersen, L.; Lægsgaard, E.; Besenbacher, F.; Linderoth, T. R.; Thomsen, A. H.; Nielsen, M.; Gothelf, K. V. J. Phys. Chem. B. 2007111, 5850-5860, https://doi.org/10.1021/jp0707891


Rearrangement of s-(2-Aminoethyl) Thiophosphates to n-(2-Mercaptoethyl)Phosphoramidates Chen, M.; Maetzke, A.; Knak Jensen, S. J.; Gothelf, K. V. Eur. J. Org. Chem. 2007, 5826-5833, doi.org/10.1002/ejoc.200700646


Control and Selectivity of Photosensitized Singlet Oxygen Production: Challenges in Complex Biological Systems Cló, E.; Snyder, J. W.; Ogilby, P. R.; Gothelf, K. V. ChemBioChem 20078, 475-481, https://doi.org/10.1002/cbic.200600454


An Electrochemical Sensor Based on the Human Estrogen Receptor Ligand Binding Domain Hansen, J. A.; Sumbayev, V. V.; Gothelf, K. V.Nano Lett. 20077, 2831-2834, https://doi.org/10.1021/nl071451l


Synthesis of Rigid Homo- and Heteroditopic Nucleobase-Terminated Molecules Incorporating Adenine and/or Thymine Jacobsen, M. F.; Andersen, C. S.; Knudsen, M. M.; Gothelf, K. V. Org. Lett. 20079, 2851-2854, doi.org/10.1021/ol071006x


Model Systems for Activation of Nucleic Acid Encoded Prodrugs Jacobsen, M. F.; Cló, E., Mokhir, A.; Gothelf, K. V. ChemMedChem 20072, 793-799, https://doi.org/10.1002/cmdc.200700013


Covalent Interlinking of an Aldehyde and an Amine on a Au(111) Surface in Ultrahigh Vacuum Weigelt, S.; Busse, C.; Bombis, C.; Knudsen, M. M.; Gothelf, K. V.; Strunskus, T.; Wöll, C.; Dahlbom, M.; Hammer, B.; Lægsgaard, E.; Besenbacher, F.; Linderoth, T. R. Angew. Chem. Int. Ed. 200746, 9227-9230, doi.org/10.1002/anie.200702859


Influence of Molecular Geometry on the Adsorption Orientation for Oligophenylene-Ethynylenes on Au(111) Weigelt, S.; Busse, C.; Nielsen, M.; Gothelf, K. V.; Lægsgaard, E.; Besenbacher, F.; Linderoth, T. R. J. Phys. Chem. B. 2007111, 11342-11345, doi.org/10.1021/jp075123l

Publications 2006


Synthesis of an Elongated Linear Oligo(Phenylene Ethynylene)-Based Building Block for Application in DNA-Programmed Assembly Blakskjær, P.; Gothelf, K. V. Org. Biomol. Chem.20064, 3442-3447, doi.org/10.1039/B605844B


DNA-Programmed Control of Photosensitized Singlet Oxygen Production Cló, E.; Snyder, J. W.; Voigt, N. V.; Ogilby, P. R.; Gothelf, K. V. J. Am. Chem. Soc. 2006128, 4200-4201, doi.org/10.1021/ja058713a


Femtomolar Electrochemical Detection of DNA Targets Using Metal Sulfide Nanoparticles Hansen, J. A.; Mukhopadhyay, R.; Hansen, J. Ø.; Gothelf, K. V. J. Am. Chem. Soc. 2006128, 3860-3861, doi.org/10.1021/ja0574116


Quantum-Dot/Aptamer-Based Ultrasensitive Multi-Analyte Electrochemical Biosensor Hansen, J. A.; Wang, J.; Kawde, A.-N.; Xiang, Y.; Gothelf, K. V.; Collins, G. J. Am. Chem. Soc.2006128, 2228-2229, doi.org/10.1021/ja060005h


A Cleavable Amino-Thiol Linker for Reversible Linking of Amines to DNA Højfeldt, J. W.; Blakskjær, P.; Gothelf, K. V. J. Org. Chem. 200671, 9556-9557, https://doi.org/10.1021/jo0619736


Efficient N-Arylation and N-Alkenylation of the Five DNA/RNA Nucleobases Jacobsen, M. F., Knudsen, M. M.; Gothelf, K. V. J. Org. Chem. 200671, 9183-9190, https://doi.org/10.1021/jo061694i


Chiral Switching by Spontaneous Conformational Change in Adsorbed Organic Molecules Weigelt, S.; Busse, C.; Petersen, L.; Rauls, E.; Hammer, B.; Gothelf, K. V.; Besenbacher, F.; Linderoth, T. R. Nature Mater. 20065, 112-117, doi.org/10.1038/nmat1558

Publications 2005


Effect of Water on the Palladium-Catalyzed Amidation of Aryl Bromides Dallas, A. S.; Gothelf, K. V. J. Org. Chem. 200570, 3321-3323, doi.org/10.1021/jo0500176


A Modular Approach to DNA-Programmed Self-Assembly of Macromolecular Nanostructures Gothelf, K. V.; Brown, R. S. Chem. Eur. J. 200511, 1062-1069, https://doi.org/10.1002/chem.200400646


DNA-Programmed Assembly of Nanostructures Gothelf, K. V.; LaBean, T. H. Org. Biomol. Chem.20053, 4023-4037, doi.org/10.1039/b510551j


Preparation Temperature Dependence of Size and Polydispersity of Alkylthiol Monolayer Protected Gold Clusters Jørgensen, J. M.; Erlacher, K.; Pedersen, J. S.; Gothelf, K. V. Langmuir 200521, 10320-10323, doi.org/10.1021/la051770x


Electrochemical Properties of Mixed Self-Assembled Monolayers on Gold Electrodes Containing Mercaptooctylhydroquinone and Alkylthiols Larsen, A. G.; Gothelf, K. V. Langmuir 200521, 1015-1021, doi.org/10.1021/la048221w


Two-Photon Photosensitized Production of Singlet Oxygen: Sensitizers with Phenylene-Ethynylene-Based Chromophores McIlroy, S. P.; Cló, E.; Nikolajsen, L.; Frederiksen, P. K.; Nielsen, C. B.; Mikkelsen, K. V.; Gothelf, K. V.; Ogilby, P. R. J. Org. Chem. 200570, 1134-1146, doi.org/10.1021/jo0482099


DNA-Directed Coupling of Organic Modules by Multiple Parallel Reductive Aminations and Subsequent Cleavage of Selected DNA Sequences Nielsen, M.; Dauksaite, V.; Kjems, J.; Gothelf, K. V. Bioconjugate Chem. 200516, 981-985, doi.org/10.1021/bc0500793


Formation and Structure of Conjugated Salen-Cross-Linked Polymers and Their Application in Asymmetric Heterogeneous Catalysis Nielsen, M.; Thomsen, A. H.; Jensen, T. R.; Jakobsen, H. J.; Skibsted, J.; Gothelf, K. V. Eur. J. Org. Chem. 20052005, 342-347, doi.org/10.1002/ejoc.200400451

Publications before 2005


Self-Assembly of Aluminium-Salen Coupled Nanostructures From Encoded Modules With Cleavable Disulfide DNA-Linkers Brown, R. S.; Nielsen, M.; Gothelf, K. V. Chem. Commun. 20040, 1464-1465, https://doi.org/10.1039/B403956D


Modular DNA-Programmed Assembly of Linear and Branched Conjugated Nanostructures Gothelf, K. V.; Thomsen, A.; Nielsen, M.; Cló, E.; Brown, R. S. J. Am. Chem. Soc. 2004126, 1044-1046, doi.org/10.1021/ja038333u


An Electrochemical Quartz Crystal Microbalance Study of the Etching of Gold Surfaces in the Presence of Tetramethylthiourea Larsen, A. G.; Johannsen, K.; Gothelf, K. V. J. Colloid Interface Sci. 2004279, 158-166, https://doi.org/10.1016/j.jcis.2004.06.007


Synthesis of Linear and Tripoidal Oligo(Phenylene Ethynylene)-Based Building Blocks for Application in Modular DNA-Programmed Assembly Nielsen, M.; Thomsen, A. H.; Cló, E.; Kirpekar, F.; Gothelf, K. V. J. Org. Chem. 200469, 2240-2250, doi.org/10.1021/jo035764m


Catalytic Asymmetric Henry Reactions of Silyl Nitronates With Aldehydes Risgaard, T.; Gothelf, K. V.; Jørgensen, K. A. Org. Biomol. Chem. 20031, 153-156, https://doi.org/10.1039/B208859M


Nucleophilic Addition of Nitrones to Ketones: Development of a New Catalytic Asymmetric Nitrone-Aldol Reaction Bøgevig, A.; Gothelf, K. V.; Jørgensen, K. A. Chem. Eur. J. 20028, 5652-5661 https://doi.org/10.1002/1521-3765(20021216)8:24<5652::AID-CHEM5652>3.0.CO;2-J


Catalytic Asymmetric 1,3-Dipolar Cycloaddition Reactions of Azomethine Ylides – A Simple Approach to Optically Active Highly Functionalized Proline Derivatives Gothelf, A. S.; Gothelf, K. V.; Hazell, R. G.; Jørgensen, K. A. Angew. Chem. Int. Ed. 200241, 4236-4238, doi.org/10.1002/1521-3773(20021115)41:22<4236::AID-ANIE4236>3.0.CO;2-W


Attachment of Alkyltrichlorosilanes to the Terminal 3,5-Dihydroxyphenyl Moiety of a Self-Assembled Thiol Monolayer on Gold Gothelf, K. V.; Larsen, A. G. J. Coll. Int. Sci.2002255, 356-362, doi.org/10.1006/jcis.2002.8672


Electron Transfer Reactions of Self- Assembled Monolayers of Thio(Phenylacetylene)n-Substituted Chiral Metal-Salen Complexes Nielsen, M.; Larsen, N. B.; Gothelf, K. V. Langmuir 200218, 2795-2799, https://doi.org/10.1021/la015715+


Density Functional Theory Study of Enantiospecific Adsorption at Chiral Surfaces Šljivancanin, Z.; Gothelf, K. V.; Hammer, B. J. Am. Chem. Soc. 2002124, 14789-14794, https://doi.org/10.1021/ja027239v


The First Catalytic Asymmetric Aza-Henry Reaction of Nitronates with Imines: A Novel Approach to Optically Active β-Nitro-α-amino acid- and α-Diamino Acid Derivatives Knudsen, K. R.; Risgaard, T.; Nishiwaki, N.; Gothelf, K. V.; Jørgensen, K. A. J. Am. Chem. Soc. 2001123, 5843-5844, doi.org/10.1021/ja010588p


Synthesis and Catalytic Properties of p-Acylthio(Phenylacetylene)n Substituted Chiral Manganese Salen Complexes Nielsen, M.; Gothelf, K. V. J. Chem. Soc., Perkin Trans. 1 2001, 2440-2444, https://doi.org/10.1039/B104103G


Catalytic Enantioselective Addition of Nitro Compounds to Imines – A Simple Approach for the Synthesis of Optically Active β-Nitro-α-Amino Esters Nishiwaki, N.; Knudsen, K. R.; Gothelf, K. V.; Jørgensen, K. A. Angew. Chem. Int. Ed. 2001113, 3080-3083, https://doi.org/10.1002/1521-3757(20010817)113:16<3080::AID-ANGE3080>3.0.CO;2-U


Self-Assembled Monolayers of Long-chain Xanthic Acids on Gold Studied by Voltammetry Gothelf, K. V. J. Electroanal. Chem. 2000494, 147-150, https://doi.org/10.1016/S0022-0728(00)00377-6


Catalytic Enantioselective 1,3-Dipolar Cycloaddition Reactions of Nitrones Gothelf, K. V., Jørgensen, K. A. Chem. Commun.200016,1449-1458, https://doi.org/10.1021/jo001157c. Featured Article.


Catalytic Enantioselective Inverse-Electron Demand 1,3-Dipolar Cycloaddition Reactions of Nitrones With Alkenes Simonsen, K. B.; Bayón, P.; Hazell, R. G.; Gothelf, K. V.; Jørgensen, K. A. J. Am. Chem. Soc. 1999121, 3845-3853, doi.org/10.1021/ja983915a


Molecular Sieve Dependent Absolute Stereoselectivity in Asymmetric Catalytic 1,3-Dipolar Cycloaddition Reactions Gothelf, K. V.; Hazell, R. G.; Jørgensen, K. A. J. Org. Chem. 199863, 5483-5488, https://doi.org/10.1021/jo980386k


Asymmetric 1,3-Dipolar Cycloaddition Reactions Gothelf, K. V.; Jørgensen, K. A. Chem. Rev. 199898, 863-910, https://doi.org/10.1021/cr970324e


A Simple Synthetic Approach to 3,3’-Diaryl BINOLs Simonsen, K. B.; Gothelf, K. V.; Jørgensen, K. A. J. Org. Chem. 199863, 7536-7538, https://doi.org/10.1021/jo980959t


On the Structure of C,N-Diphenylnitrone in 1,3-Dipolar Cycloaddition Reactions Gothelf, K. V.; Hazell, R. G.; Jørgensen, K. A. Acta Chem. Scand. 199751, 1234-1235, https://doi.org/10.3891/acta.chem.scand.51-1234


On the Trans-c´Cis Controversy in Ti-TADDOLate-Catalysed Cycloadditions. Experimental Indications for the Structure of the Reactive Catalyst-Substrate Intermediate Gothelf, K. V.; Jørgensen, K. A. J. Chem. Soc., Perkin Trans. 2 1997, 111–116, https://doi.org/10.1039/A602735K


Improvement of TADDOLate-TiCl2-Catalyzed 1,3-Dipolar Nitrone Cycloaddition Reactions by Substitution of the Oxazolidinone Auxiliary of the Alkene With Succinimide Jensen, K. B.; Gothelf, K. V.; Hazell, R. G.; Jørgensen, K. A. J. Org. Chem. 199762, 2471-2477, doi.org/10.1021/jo962214y


Control of Regio-, Diastereo-, and Enantioselectivity in the [Ti(OTs)2(TADDOLato)]-Catalyzed 1,3-Dipolar Cycloaddition Reaction Between 3-Acryloyloxazolidin-2-One and Nitrones Jensen, K. B.; Gothelf, K. V.; Jørgensen, K. A. Helv. Chim. Acta 199780, 2039-2046, https://doi.org/10.1002/hlca.19970800704


Lanthanide-Catalyzed Endo- And Enantioselective 1,3-Dipolar Cycloaddition Reactions of Nitrones With Alkenes Sanchez-Blanco, A. I.; Gothelf, K. V.; Jørgensen, K. A. Tetrahedron Lett. 199738, 7923-7926, doi.org/10.1016/S0040-4039(97)10048-X


Control of Diastereo- and Enantioselectivity in Metal-Catalyzed 1,3-Dipolar Cycloaddition Reactions of Nitrones with Alkenes. Experimental and Theoretical Investigations Gothelf, K. V.; Hazell, R. G.; Jørgensen, K. A. J. Org. Chem. 199661, 346-355, https://doi.org/10.1021/jo951204e


Metal-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition Reactions Gothelf, K. V.; Jørgensen, K. A. Acta Chem. Scand. 199650, 652-660, https://doi.org/10.3891/acta.chem.scand.50-0652


A Highly Diastereoselective and Enantioselective Ti(OTos)2-TADDOLate-Catalyzed 1,3-Dipolar Cycloaddition Reaction of Alkenes With Nitrones Gothelf, K. V.; Thomsen, I.; Jørgensen, K. A. J. Am. Chem. Soc. 1996118, 59-64, https://doi.org/10.1021/ja952726e


Crystal Structure of a Chiral Titanium Catalyst-Alkene Complex. The Intermediate in Catalytic Asymmetric Diels-Alder and 1,3-Dipolar Cycloaddition Reactions Gothelf, K. V.; Hazell, R. G.; Jørgensen, K. A. J. Am. Chem. Soc. 1995117, 4435-4436, https://doi.org/10.1021/ja00120a041


On the Mechanism of Ti-TADDOLate-Catalyzed Asymmetric Diels-Alder Reactions Gothelf, K. V.; Jørgensen, K. A. J. Org. Chem.199560, 6847-6851, https://doi.org/10.1021/jo00126a039


Transition-Metal Catalyzed Asymmetric 1,3-Dipolar Cycloaddition Reactions Between Alkenes and Nitrones Gothelf, K. V.; Jørgensen, K. A. J. Org. Chem.199459, 5687-5691, https://doi.org/10.1021/jo00098a029


Synthesis of 2,8-Diarylpyrano[3,2-g]Chromene-4,6-Diones Gothelf, K. V.; Torssell, K. B. G. Acta Chem. Scand. 199448, 165-168, https://doi.org/10.3891/acta.chem.scand.48-0165


Synthesis of Flavones via Application of Nitrile Oxide and the Stille Reactions Gothelf, K. V.; Torssell, K. B. G. Acta Chem. Scand. 199448, 61-67, https://doi.org/10.3891/acta.chem.scand.48-0061


A Convenient Synthesis of Flavones. Synthesis of Apigenin Gothelf, K. V.; Thomsen, I.; Torssell, K. B. G. Acta Chem. Scand. 199246, 494-495, https://doi.org/10.3891/acta.chem.scand.46-0494