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Nanomedicine - Jørgen Kjems Group

Jørgen Kjems Group

Nanomedicine

The Kjems lab is located at the interdisciplinary Nanoscience center (INANO) and at the Department of Molecular Biology and Genetics (MBG), both parts of Aarhus University.


MAIN FOCUS AREAS IN THE LAB:

-> Constructing functionalised self-assembled DNA and RNA nanostructures capable of complex biosensing, coupled with controlled action such as drug release, enzyme activation and receptor signalling.

 -> Understanding the biogenesis and function of small non-coding RNAs and circular RNAs. In particular, we're interested in how circRNAs are formed in the cell and how they function in development and disease.

 -> The creation of novel bioimaging and delivery systems for gene medicine including small RNAs, nanobodies and Cas9 with a specific focus on inflammation, cancer, influenza and tissue regeneration.

 -> Using DNA and RNA aptamers for targeted delivery, detection and inhibition of viral proteins and to profile complex biological samples.