-> Constructing functionalised self-assembled DNA and RNA nanostructures capable of complex biosensing, coupled with controlled action such as drug release, enzyme activation and receptor signalling.
-> Understanding the biogenesis and function of small non-coding RNAs and circular RNAs. In particular, we're interested in how circRNAs are formed in the cell and how they function in development and disease.
-> The creation of novel bioimaging and delivery systems for gene medicine including small RNAs, nanobodies and Cas9 with a specific focus on inflammation, cancer, influenza and tissue regeneration.
-> Using DNA and RNA aptamers for targeted delivery, detection and inhibition of viral proteins and to profile complex biological samples.