Research

There are three main focus areas of The Scientist's group:

a) The understanding of how small non-coding RNA and circular RNA contribute to cell maintenance and disease development with a primary aim of defining new targets for disease intervention.

b) The creation of novel bioimaging and delivery systems for gene medicine including siRNA, miRNA mimics, antimiRs (antisense targeting microRNA) with a specific focus on inflammation, cancer, influenza, and regeneration of damaged tissue (tissue engineering).

c) Design and construction of functionalized self assembled DNA and RNA nanostructures capable of complex biosensing, coupled with controlled action e.g. drug release, enzyme activation, and receptor signaling.

Recent publications

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Mai, Y., Zhang, D., Maliutina, K., Leng, X., Cai, N., Li, J., Wang, C., Huang, Y., Zhang, K., Zhang, W., Li, Y., Besenbacher, F., Niemantsverdriet, H., Liang, W., Shen, Y., Lim, T., Richards, E. & Su, R. (2025). Photocatalytic Partial Water Oxidation Promoted by a Hydrogen Acceptor-Hydroxyl Mediator Couple. Advanced Science, 12(6), Article 2410680. https://doi.org/10.1002/advs.202410680

Lu, Y., Luo, R., Leng, X., Huang, Y., Jiang, W., Besenbacher, F., Li, Y., Yin, W. & Su, R. (2025). Water-Promoted Molar-Level Photocatalysis and Spontaneous Product Separation with Near-Unity Quantum Efficiency. Journal of the American Chemical Society, 147(49), 45240-45248. https://doi.org/10.1021/jacs.5c15003

Chen, Y., Ding, P., Sun, Y., Kantorovich, L. N., Besenbacher, F. & Yu, M. (2024). Highly-selective metalation of porphyrin enabled by distinct aromatic ring-fused structures. Materials Today Physics, 42, Article 101392. https://doi.org/10.1016/j.mtphys.2024.101392

Huang, Y., Li, Y., Zhang, D., Mai, Y., Besenbacher, F., Dong, C., Rosei, F., Yang, Y., Li, Y., Niemantsverdriet, H., Liang, W. & Su, R. (2024). Light-Switchable N-Alkylation Using Amine-Functionalized MOF. Applied Catalysis B: Environment and Energy, 350, Article 123924. https://doi.org/10.1016/j.apcatb.2024.123924

Wang, Y., Han, Y., Yang, C., Bai, T., Zhang, C., Wang, Z., Sun, Y., Hu, Y., Besenbacher, F., Chen, C. & Yu, M. (2024). Long-term relapse-free survival enabled by integrating targeted antibacteria in antitumor treatment. Nature Communications, 15(1), Article 4194. https://doi.org/10.1038/s41467-024-48662-x

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Group leader

Group members

Full list of publications

Revised 08.12.2025

Lise Refstrup Linnebjerg Pedersen