Research

There are three main focus areas of The Scientist's group:

a) The understanding of how small non-coding RNA and circular RNA contribute to cell maintenance and disease development with a primary aim of defining new targets for disease intervention.

b) The creation of novel bioimaging and delivery systems for gene medicine including siRNA, miRNA mimics, antimiRs (antisense targeting microRNA) with a specific focus on inflammation, cancer, influenza, and regeneration of damaged tissue (tissue engineering).

c) Design and construction of functionalized self assembled DNA and RNA nanostructures capable of complex biosensing, coupled with controlled action e.g. drug release, enzyme activation, and receptor signaling.

Recent publications

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Helveg, S., Lauritsen, J. V., Lægsgaard, E., Stensgaard, I., Nørskov, J. K., Clausen, B. S., Topsøe, H. & Besenbacher, F. (2000). Atomic-scale structure of single-layer MoS₂ nano-clusters. Physical Review Letters, 84, 951.

Morgenstern, K., Rosenfeld, G., Comsa, G., Lægsgaard, E. & Besenbacher, F. (2000). Comment on "Interlayer mass transport and quantum confinement of electronic states" by Giesen et al. in Phys.Rev.Lett. 80, 552(1998) and PRL 82, 3101 (1999). Physical Review Letters, 85, 468.

Hansen, K., Nielsen, S. K., Brandbyge, M., Lægsgaard, E., Stensgaard, I. & Besenbacher, F. (2000). Current-voltage curves of gold quantum point contacts revisited. Applied Physics Letters, 77, 708.

Pedersen, M. Ø., Österlund, L., Mortensen, J. J., Mavrikakis, M., Hansen, L. B., Stensgaard, I., Lægsgaard, E., Nørskov, J. K. & Besenbacher, F. (2000). Diffusion of N adatoms on the Fe(100) surface. Physical Review Letters, 84, 4898.

Linderoth, T. R., Horch, S., Petersen, L., Helveg, S., Schønning, M., Lægsgaard, E., Stensgaard, I. & Besenbacher, F. (2000). Energetics and dynamics of Pt dimers on Pt(110)-(1x2). Physical Review B, 61, 2448-2448.

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