Research

There are three main focus areas of The Scientist's group:

a) The understanding of how small non-coding RNA and circular RNA contribute to cell maintenance and disease development with a primary aim of defining new targets for disease intervention.

b) The creation of novel bioimaging and delivery systems for gene medicine including siRNA, miRNA mimics, antimiRs (antisense targeting microRNA) with a specific focus on inflammation, cancer, influenza, and regeneration of damaged tissue (tissue engineering).

c) Design and construction of functionalized self assembled DNA and RNA nanostructures capable of complex biosensing, coupled with controlled action e.g. drug release, enzyme activation, and receptor signaling.

Recent publications

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Wang, Y., Han, Y., Yang, C., Bai, T., Zhang, C., Wang, Z., Sun, Y., Hu, Y., Besenbacher, F., Chen, C. & Yu, M. (2024). Long-term relapse-free survival enabled by integrating targeted antibacteria in antitumor treatment. Nature Communications, 15(1), Article 4194. https://doi.org/10.1038/s41467-024-48662-x

Li, Y., Zhang, D., Ye, J., Mai, Y., Wang, C., Yang, Y., Li, Y., Besenbacher, F., Niemantsverdriet, H., Rosei, F., Pan, F. & Su, R. (2023). A Modular Tubular Flow System with Replaceable Photocatalyst Membranes for Scalable Coupling and Hydrogenation. Angewandte Chemie - International Edition, 62(22), Article e202302979. https://doi.org/10.1002/anie.202302979

Qiao, W., Fan, X., Liu, W., Khan, F. N., Zhang, D., Han, F., Yue, H., Li, Y., Dimitratos, N., Albonetti, S., Wen, X., Yang, Y., Besenbacher, F., Li, Y., Niemantsverdriet, H., Lin, H. & Su, R. (2023). Creating and Stabilizing an Oxidized Pd Surface under Reductive Conditions for Photocatalytic Hydrogenation of Aromatic Carbonyls. Journal of the American Chemical Society, 145(9), 5353-5362. https://doi.org/10.1021/jacs.2c13196

Wang, C., Li, J., Shao, T., Zhang, D., Mai, Y., Li, Y., Besenbacher, F., Niemantsverdriet, H., Rosei, F., Zhong, J. & Su, R. (2023). Electric Field Enhanced Ammoxidation of Aldehydes Using Supported Fe Clusters Under Ambient Oxygen Pressure. Angewandte Chemie - International Edition, 62(51), Article e202313313. https://doi.org/10.1002/anie.202313313

Ding, P., Wang, S., Mattioli, C., Li, Z., Shi, G., Sun, Y., Gourdon, A., Kantorovich, L., Besenbacher, F., Rosei, F. & Yu, M. (2023). Extending on-surface synthesis from 2D to 3D by cycloaddition with C₆₀. Nature Communications, 14(1), Article 6075. https://doi.org/10.1038/s41467-023-41913-3

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Group leader

Group members

Full list of publications

Revised 08.12.2025

Lise Refstrup Linnebjerg Pedersen