Aarhus Universitets segl

Protein Biophysics (Prof. Daniel Otzen)

Daniel Otzen

Professor Interdisciplinary Nanoscience Center - INANO-MBG, iNANO-huset

Facilities

News
Publications
Group members
Research funding

Research focus in brief

Our research activities fall within 3 main areas, which all relate to the study of the kinetics and thermodynamics of protein conformational changes, namely membrane protein folding, protein-detergent interactions and protein fibrillation. These areas are linked by a keen interest in understanding the mechanistic and thermodynamic behaviour of proteins in different circumstances by quantifying the strength of internal side-chain interactions as well as contacts with solvent molecules, whether it be detergents, denaturants, stabilizing salts and osmolytes or lipids. Ultimately we hope this will lead to a greater manipulative ability vis-a-vis processes of both basic, pharmaceutical and industrial relevance. The general approach is to use available spectroscopic techniques (fluorescence, CD, stopped-flow, FTIR, NMR and dynamic and static light scattering) to generate data which can be analyzed in a quantitative manner to develop models and mechanisms for conformational changes at the molecular level.  

Read more here

News

Birgit Schiøtt receives two grants for the study of neurotransmitters

- Research news

The Serotonergic Synapse and Modeling the Dopamine Transporter are projects aiming to increase the understanding of the neurotransmitters, which will…

Jeppe V. Lauritsen receives funding for synthetic fuel production research

- Research News

The Danish Council of Independent Research has granted funds to carry out Atomic-scale studies of iron-based Fischer-Tropsch catalyst. …

iNANO and Shanghai researchers improve photoelectrocatalysis of water oxidation

- iNano

A large part of total world energy consumption is derived from non-renewable fossil fuels. Replacing this source of energy by solar energy via…

Recent publications

Sortér efter: Dato | Forfatter | Titel