Aarhus Universitets segl

Protein Biophysics (Prof. Daniel Otzen)

Daniel Otzen

Professor Interdisciplinary Nanoscience Center - INANO-MBG, iNANO-huset

Facilities

News
Publications
Group members
Research funding

Research focus in brief

Our research activities fall within 3 main areas, which all relate to the study of the kinetics and thermodynamics of protein conformational changes, namely membrane protein folding, protein-detergent interactions and protein fibrillation. These areas are linked by a keen interest in understanding the mechanistic and thermodynamic behaviour of proteins in different circumstances by quantifying the strength of internal side-chain interactions as well as contacts with solvent molecules, whether it be detergents, denaturants, stabilizing salts and osmolytes or lipids. Ultimately we hope this will lead to a greater manipulative ability vis-a-vis processes of both basic, pharmaceutical and industrial relevance. The general approach is to use available spectroscopic techniques (fluorescence, CD, stopped-flow, FTIR, NMR and dynamic and static light scattering) to generate data which can be analyzed in a quantitative manner to develop models and mechanisms for conformational changes at the molecular level.  

Read more here

News

Circularity solution to end landfill for turbine blades

Professor Troels Skrydstrup is part of the CETEC initiative where they collaborate on elimination of waste across the wind energy industry. Photo: The Novo Nordisk Foundation.

Aarhus University and Troels Skrydstrup's research group have, as CETEC partner, contributed with the technology to render epoxy-based turbine blades…

High school teachers and researchers inspire each other across science subjects

At the exhibition stands, the participants could be inspired for teaching with suggestions for professional class visits and teaching material. Photo: Julie Nørgaard Hostrup

High school teachers teaching various science subjects gathered on Friday, January 27, at the Faculty of Natural Sciences for a joint day of…

Cut-chemistry for a greener world

Inauguration of new center for plastic research, En'Zync, at iNANO, Aarhus University. Photo: Lise R. L. Pedersen, AU

We produce more than 400 million tonnes of plastic in the world every year. Plastic has many good functions, but we have not yet solved the big…

Recent publications

Sortér efter: Dato | Forfatter | Titel