Aarhus Universitets segl

Protein Biophysics (Prof. Daniel Otzen)

Daniel Erik Otzen

Professor Interdisciplinary Nanoscience Center - INANO-MBG, iNANO-huset


Group members
Research funding

Research focus in brief

Our research activities fall within 3 main areas, which all relate to the study of the kinetics and thermodynamics of protein conformational changes, namely membrane protein folding, protein-detergent interactions and protein fibrillation. These areas are linked by a keen interest in understanding the mechanistic and thermodynamic behaviour of proteins in different circumstances by quantifying the strength of internal side-chain interactions as well as contacts with solvent molecules, whether it be detergents, denaturants, stabilizing salts and osmolytes or lipids. Ultimately we hope this will lead to a greater manipulative ability vis-a-vis processes of both basic, pharmaceutical and industrial relevance. The general approach is to use available spectroscopic techniques (fluorescence, CD, stopped-flow, FTIR, NMR and dynamic and static light scattering) to generate data which can be analyzed in a quantitative manner to develop models and mechanisms for conformational changes at the molecular level.  

Read more here


Rikke Meyer and Dorthe Ravnsbæk join The Royal Academy of Sciences and Letters

Professor Rikke Louise Meyer and Professor Dorthe Ravnsbæk from iNANO become members of the Royal Academy of Sciences and Letters.

We are proud to announce that iNANO researchers Professor Rikke Meyer and Professor Dorthe Ravnsbæk, have been inducted as members of The Royal…

Green methanol production: Visualizing methanol synthesis catalyst surface dynamics

A team of scientists from the Interdisciplinary Nanoscience center led by Prof. Jeppe V. Lauritsen have obtained important new insight into the industrially applied catalyst used to convert captured CO2 and H2 gas into green methanol – a key energy carrier in the replacement of fossil fuels.

A research team from iNANO, led by Prof. Jeppe V. Lauritsen, has made discoveries about the industrial catalyst used to convert captured CO₂ and H₂…

Recent publications

Sortér efter: Dato | Forfatter | Titel