Rikvold, P. D., K. Johnsen, K., Del Rey, Y. C., Knap, I., Holz, C.
, Meyer, R. L., Jørgensen, M. R.
& Schlafer, S. (2025).
A randomized controlled trial on the effect of multiple-enzyme treatment on dental plaque formation.
Caries Research,
59(4).
https://doi.org/10.1159/000546564
Rikvold, P. D., K. Johnsen, K., Del Rey, Y. C., Knap, I., Holz, C.
, Meyer, R. L., Jørgensen, M. R.
& Schlafer, S. (2025).
A randomized controlled trial on the effect of multiple-enzyme treatment on dental plaque formation.
Rikvold, P., K. Johnsen, K., Chokyu Del Rey, Y., Knap, I., Holz, C.
, Meyer, R. L., Jørgensen, M. R.
& Schlafer, S. (2025).
A randomized controlled trial on the effect of multiple-enzyme treatment on dental plaque formation. Poster session presented at ORCA: 72nd Congress of the European Organization for Caries Research, Leeds, United Kingdom.
Rikvold, P., K. Johnsen, K., Chokyu Del Rey, Y., Knap, I., Holz, C.
, Meyer, R. L., Jørgensen, M. R.
& Schlafer, S. (2025).
A randomized controlled trial on the effect of multiple-enzyme treatment on the microbial plaque composition.
Caries Research,
59, 321.
https://doi.org/10.1159/000546564
Schlafer, S., K. Johnsen, K., Chokyu Del Rey, Y., Meyer, R. L., Skov Hansen, L. B., Knap, I., Holz, C., Jørgensen, M. R.
& Rikvold, P. (2025).
A randomized controlled trial on the effect of multiple-enzyme treatment on the microbial plaque composition. Poster session presented at ORCA: 72nd Congress of the European Organization for Caries Research, Leeds, United Kingdom.
Chokyu Del Rey, Y., Rikvold, P., Lund, M. B., Raittio, E., Schramm, A., Meyer, R. L. & Schlafer, S. (2025).
Arginine mitigates pH drops and modulates the composition and architecture of biofilms from caries-active patients. Abstract from ORCA: 72nd Congress of the European Organization for Caries Research, Leeds, United Kingdom.
Chokyu Del Rey, Y., Rikvold, P., Lund, M. B., Raittio, E., Schramm, A., Meyer, R. L. & Schlafer, S. (2025).
Arginine mitigates pH drops and modulates the composition and architecture of biofilms from caries-active patients. Poster session presented at ORCA: 72nd Congress of the European Organization for Caries Research, Leeds, United Kingdom.
Del Rey, Y. C., Rikvold, P. D., Lund, M. B., Raittio, E. J., Schramm, A., Meyer, R. L. & Schlafer, S. (2025).
Arginine modulates the pH, microbial composition, and matrix architecture of biofilms from caries-active patients.
International Journal of Oral Science,
17(1), Article 70.
https://doi.org/10.1038/s41368-025-00404-5
Seefeldt, A. M.
, Johansen, M. I., Sillesen, F. W., Petersen, M. E., Østergaard, L., Meyer, R. L. & Jørgensen, N. P. (2025).
Bithionol is ineffective in a mouse model of S. aureus implant-associated osteomyelitis despite potent in vitro activity.
Scientific Reports,
15(1), Article 24156.
https://doi.org/10.1038/s41598-025-08879-2Dybtved, M. S., Petersen, M. E., Firdausy, A. F., Johansen, M. I., Faddy, E., Gadeberg, C., Østergaard, L., Jørgensen, N. P., Glud, L. N., Søgaard, A. B., Meyer, R. L. & Zelikin, A. N. (2025).
Broad-Spectrum Antimicrobial Treatment Targeted Through Drug Conjugation to Vancomycin.
Advanced Healthcare Materials, Article e03932. Advance online publication.
https://doi.org/10.1002/adhm.202503932
Golletz, P.
, Jensen, S. D., Collignon, M., Hall, C.
, Khamas, A. B., Møllebjerg, A., Schlafer, S., Meyer, R. L. & Tykwinska, K. (2025).
Coaggregation of oral pathogens by postbiotic lactobacilli.
Journal of Oral Microbiology,
17(1), Article 2508483.
https://doi.org/10.1080/20002297.2025.2508483Petersen, M. E., Khamas, A. B., Østergaard, L. J., Jørgensen, N. P. & Meyer, R. L. (2025).
Combination therapy delays antimicrobial resistance after adaptive laboratory evolution of Staphylococcus aureus.
Antimicrobial Agents and Chemotherapy,
69(4), Article e01483-24.
https://doi.org/10.1128/aac.01483-24
Evans, D. C. S., Raittio, E. J., Lund, M. B., Meyer, R. L., Schlafer, S. & Kristensen, M. F. (2025).
Correlative imaging of extracellular DNA and pH at the microscale in the extracellular matrix of dental biofilms.
Journal of Microbiological Methods,
239, Article 107298.
https://doi.org/10.1016/j.mimet.2025.107298
Kristensen, M. F., Schlafer, S., Meyer, R. L., Lund, M. B. & Evans, D. C. (2025).
Correlative imaging of pH and extracellular DNA in dental biofilms. Poster session presented at ORCA: 72nd Congress of the European Organization for Caries Research, Leeds, United Kingdom.
Evans, D. C. S., Kristensen, M. F., Minero, G. A. S., Palmén, L. G., Knap, I., Tiwari, M. K.
, Schlafer, S. & Meyer, R. L. (2025).
Dental biofilms contain DNase I-resistant Z-DNA and G-quadruplexes but alternative DNase overcomes this resistance.
npj Biofilms and Microbiomes,
11(1), Article 80.
https://doi.org/10.1038/s41522-025-00694-x
Zhang, T., Bär, J., Risberg, L., Gómez Mejia, A., Hammar, H., Löffler, S.
, Otzen, D. E., Andreasen, M., Meyer, R. L., Melican, K., Zinkernagel, A. S. & Richter-Dahlfors, A. (2025).
Dynamic visualization of extracellular matrix components in S. aureus colony biofilms reveals functional amyloids leading to the formation of cap-like structures.
Biofilm,
10, Article 100318.
https://doi.org/10.1016/j.bioflm.2025.100318Assar, S., Kristensen, M. F., Del Rey, Y. C., Lund, M. B., Raittio, E. J., Schramm, A., Meyer, R. L. & Schlafer, S. (2025).
Microscale analyses of the effect of arginine on oral biofilms.
Journal of Dentistry,
160, Article 105863.
https://doi.org/10.1016/j.jdent.2025.105863
Faddy, E., Johansen, M. I., Gadeberg, C., Meyer, R. L., Østergaard, L., Bay-Richter, C., Jensen, L. K.
, Vendelbo, M. H. & Jørgensen, N. P. (2025).
[18F]Fluorodeoxyglucose Positron Emission Tomography for diagnosis and monitoring of acute Staphylococcus aureus vascular graft infection in a rat model.
The Journal of Infectious Diseases, Article jiaf594. Advance online publication.
https://doi.org/10.1093/infdis/jiaf594
Rikvold, P. D., Johnsen, K. K., Del Rey, Y. C., Hansen, L. B. S., Knap, I., Holz, C.
, Meyer, R. L., Jørgensen, M. R.
& Schlafer, S. (2025).
The Effect of Enzymes on Dental Plaque: A Randomized Controlled Trial.
Journal of Dental Research. Advance online publication.
https://doi.org/10.1177/00220345251347959
Rikvold, P. D., Møllebjerg, A., Raittio, E. J., Nielsen, S. M., Johnsen, K. K.
, Lund, M. B., Jørgensen, M. R.
, Meyer, R. L. & Schlafer, S. (2025).
The effect of multiple-enzyme treatment on in situ oral biofilm formation in healthy participants.
Biofilm,
10, Article 100298.
https://doi.org/10.1016/j.bioflm.2025.100298
Petersen, M. E., Hansen, L. K., Mitkin, A. A., Kelly, N. M., Wood, T. K.
, Jørgensen, N. P., Østergaard, L. J. & Meyer, R. L. (2024).
A high-throughput assay identifies molecules with antimicrobial activity against persister cells.
Journal of Medical Microbiology,
73(7), Article 001856.
https://doi.org/10.1099/jmm.0.001856
Assar, S., Chokyu Del Rey, Y., Kristensen, M. F., Lund, M. B., Raittio, E., Schramm, A., Meyer, R. L. & Schlafer, S. (2024).
Arginine decreases the production of matrix carbohydrates and stimulates eDNA release in saliva-derived dental biofilms.
Caries Research.
Assar, S., Chokyu Del Rey, Y., Kristensen, M. F., Lund, M. B., Raittio, E., Schramm, A., Meyer, R. L. & Schlafer, S. (2024).
Arginine decreases the production of matrix carbohydrates and stimulates eDNA release in saliva-derived dental biofilms. Poster session presented at ORCA - 71st Congress of the Organization for Caries Research, Heraklion, Greece.
Assar, S., Chokyu Del Rey, Y., Kristensen, M. F., Lund, M. B., Raittio, E., Schramm, A., Meyer, R. L. & Schlafer, S. (2024).
Arginine modulates the bacterial community composition and raises microscale pH in saliva-derived dental biofilms.
Caries Research,
58(3).
https://doi.org/10.1159/000539768
Assar, S., Chokyu Del Rey, Y., Kristensen, M. F., Lund, M. B., Raittio, E., Schramm, A., Meyer, R. L. & Schlafer, S. (2024).
Arginine modulates the bacterial community composition and raises microscale pH in saliva-derived dental biofilms.
Sahariah, P., Papi, F., Merz, K. L., Sigurjonsson, O. E.
, Meyer, R. L. & Nativi, C. (2024).
Chitosan–saccharide conjugates for eradication of Pseudomonas aeruginosa biofilms.
RSC Applied Polymers,
2(3), 461-472.
https://doi.org/10.1039/D3LP00263BDel Rey, Y. C., Schramm, A., L Meyer, R., Lund, M. B. & Schlafer, S. (2024).
Combined pH ratiometry and fluorescence lectin-binding analysis (pH-FLBA) for microscopy-based analyses of biofilm pH and matrix carbohydrates.
Applied and Environmental Microbiology,
90(2), Article e0200723.
https://doi.org/10.1128/aem.02007-23
Sandfeld, T., Grøn, L. V., Munoz Duarte, L. D., Meyer, R. L., Koren, K. & Philips, J. (2024).
Considerations on the use of microsensors to profile dissolved H2 concentrations in microbial electrochemical reactors.
PLoS One,
19(1), Article e0293734.
https://doi.org/10.1371/journal.pone.0293734
Evans, D. C. S., Khamas, A. B., Payne-Dwyer, A., Wollman, A. J. M., Rasmussen, K. S., Klitgaard, J. K., Kallipolitis, B., Leake, M. C.
& Meyer, R. L. (2024).
Cooperation between coagulase and von willebrand factor binding protein in Staphylococcus aureus fibrin pseudocapsule formation.
Biofilm,
8, Article 100233.
https://doi.org/10.1016/j.bioflm.2024.100233
Johansen, M. I., Petersen, M. E., Faddy, E., Seefeldt, A. M.
, Mitkin, A. A., Østergaard, L., Meyer, R. L. & Jørgensen, N. P. (2024).
Efficacy of rifampicin combination therapy against MRSA prosthetic vascular graft infections in a rat model.
Biofilm,
7, Article 100189.
https://doi.org/10.1016/j.bioflm.2024.100189
Ng, K. S., Bambace, M. F., Andersen, E. B.
, Meyer, R. L. & Schwab, C. (2024).
Environmental pH and compound structure affect the activity of short-chain carboxylic acids against planktonic growth, biofilm formation, and eradication of the food pathogen Salmonella enterica.
Microbiology Spectrum,
12(11), Article e0165824.
https://doi.org/10.1128/spectrum.01658-24
Minero, G. A. S., Møllebjerg, A., Thiesen, C., Johansen, M. I., Jørgensen, N. P., Birkedal, V., Otzen, D. E. & Meyer, R. L. (2024).
Extracellular G-quadruplexes and Z-DNA protect biofilms from DNase I, and G-quadruplexes form a DNAzyme with peroxidase activity.
Nucleic Acids Research,
52(4), 1575-1590.
https://doi.org/10.1093/nar/gkae034
Nielsen, S. M., Johnsen, K. K., Hansen, L. B. S.
, Rikvold, P. D., Møllebjerg, A., Palmén, L. G., Durhuus, T.
, Schlafer, S. & Meyer, R. L. (2024).
Large-scale screening identifies enzyme combinations that remove in situ grown oral biofilm.
Biofilm,
8, Article 100229.
https://doi.org/10.1016/j.bioflm.2024.100229Del Rey, Y. C., Kitzinger, K.
, Lund, M. B., Schramm, A., Meyer, R. L., Wagner, M.
& Schlafer, S. (2024).
pH-FISH - coupled microscale analysis of microbial identity and acid–base metabolism in complex biofilm samples.
Microbiome,
12(1), Article 266.
https://doi.org/10.1186/s40168-024-01977-9
Rikvold, P. D., Hansen Skov, L. B.
, Louise Meyer, R., Rose Jorgensen, M., Tiwari, M. K.
& Schlafer, S. (2024).
The effect of enzymatic treatment with mutanase, beta-glucanase and DNase on a saliva-derived biofilm model.
Caries Research,
58(2), 72-80.
https://doi.org/10.1159/000535980
Schlafer, S., Johnsen, K. K., Kjærbølling, I.
, Schramm, A., Meyer, R. L. & Jørgensen, M. R. (2024).
The efficacy and safety of an enzyme-containing lozenge for dental biofilm control: a randomized controlled pilot trial.
Journal of Dentistry,
147, Article 105107.
https://doi.org/10.1016/j.jdent.2024.105107
Rikvold, P. T., Johnsen, K. K., Leonhardt, D., Mollebjerg, A., Nielsen, S. M., Hansen, L. B. S.
, Meyer, R. L. & Schlafer, S. (2023).
A New Device for In Situ Dental Biofilm Collection Additively Manufactured by Direct Metal Laser Sintering and Vat Photopolymerization.
3D Printing and Additive Manufacturing,
10(5), 1036-1045.
https://doi.org/10.1089/3dp.2022.0009
Tvilum, A. S., Johansen, M. I., Glud, L. N., Ivarsen, D. M., Khamas, A. B., Carmali, S., Mhatre, S. S., Søgaard, A. B., Faddy, E., de Vor, L., H. M. Rooijakkers, S.
, Østergaard, L. J., Jørgensen, N. P., Meyer, R. L. & Zelikin, A. (2023).
Antibody-Drug Conjugates to Treat Bacterial Biofilms via Targeting and Extracellular Drug Release.
Advanced Science,
10(23), Article 2301340.
https://doi.org/10.1002/advs.202301340
Johansen, M. I., Rahbek, S. J., Jensen-Fangel, S., Minero, G. A., Jensen, L. K.
, Larsen, O. H., Erikstrup, L. T., Seefeldt, A. M.
, Østergaard, L. J., Meyer, R. L. & Jørgensen, N. P. (2023).
Fibrinolytic and antibiotic treatment of prosthetic vascular graft infections in a novel rat model.
PLoS One,
18(7), Article e0287671.
https://doi.org/10.1371/journal.pone.0287671
Evans, D. C. S., Khamas, A. B., Marcussen, L., Rasmussen, K. S., Klitgaard, J. K., Kallipolitis, B. H.
, Nielsen, J., Otzen, D. E., Leake, M. C.
& Meyer, R. L. (2023).
GFP fusions of Sec-routed extracellular proteins in Staphylococcus aureusreveal surface-associated coagulase in biofilms.
Microbial Cell,
10(7), 145-156.
https://doi.org/10.15698/mic2023.07.800
Møllebjerg, A., Zarebska, A., Nielsen, H. B., Hansen, L. B. S., Sørensen, S. R., Seredynska-Sobecka, B., Villacorte, L. O., Gori, K., Palmén, L. G.
& Meyer, R. L. (2023).
Novel high-throughput screening platform identifies enzymes to tackle biofouling on reverse osmosis membranes.
Desalination,
554, Article 116485.
https://doi.org/10.1016/j.desal.2023.116485
Wollesen, M., Mikkelsen, K., Tvilum, M. S., Vestergaard, M.
, Wang, M., Meyer, R. L., Ingmer, H.
, Poulsen, T. & Tørring, T. (2023).
Polyether Ionophore Antibiotics Target Drug-Resistant Clinical Isolates, Persister Cells, and Biofilms.
Microbiology Spectrum,
11(4), Article e0062523.
https://doi.org/10.1128/spectrum.00625-23
Pandit, S., Jacquemin, L.
, Zhang, J., Gao, Z., Nishina, Y.
, Meyer, R. L., Mijakovic, I., Bianco, A. & Pang, C. (2023).
Polymyxin B complexation enhances the antimicrobial potential of graphene oxide.
Frontiers in cellular and infection microbiology,
13, Article 1209563.
https://doi.org/10.3389/fcimb.2023.1209563
