Biofilm group (Prof. Rikke Louise Meyer)

The group

My research combines microbiology and nanotechnology in pursuit of understanding how biofilms establish, and how they can be controlled.

Investigation of fundamental mechanisms in bacterial adhesion and biofilm formation, particularly the role of extracellular DNA.
Development of new approaches to control biofilms and treat biofilm infections through targeted drug delivery, novel antibiotics and nanobiotics, and non-biocidal biofilm control with e.g. enzymes or salinity oscillation.

Hot off the press

December 2024: We just got funded by Innovationfund Denmark to continue our quest for developing targeted therapies for biofilm infections

November 2024: Check out our chapter about extracelluar nucleic acids in biofilms in the book "Biofilm Matrix" (Springer book series). I recommend the entire book, and you are welcome to have a peak at the pre-print.

Recent publications

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Petersen, M. E., Hansen, L. K., Mitkin, A. A., Kelly, N. M., Wood, T. K., Jørgensen, N. P., Østergaard, L. J. & Meyer, R. L. (2024). A high-throughput assay identifies molecules with antimicrobial activity against persister cells. Journal of Medical Microbiology, 73(7), Article 001856. https://doi.org/10.1099/jmm.0.001856

Assar, S., Chokyu Del Rey, Y., Kristensen, M. F., Lund, M. B., Raittio, E., Schramm, A., Meyer, R. L. & Schlafer, S. (2024). Arginine decreases the production of matrix carbohydrates and stimulates eDNA release in saliva-derived dental biofilms. Caries Research.

Assar, S., Chokyu Del Rey, Y., Kristensen, M. F., Lund, M. B., Raittio, E., Schramm, A., Meyer, R. L. & Schlafer, S. (2024). Arginine decreases the production of matrix carbohydrates and stimulates eDNA release in saliva-derived dental biofilms. Poster session presented at ORCA - 71st Congress of the Organization for Caries Research, Heraklion, Greece.

Assar, S., Chokyu Del Rey, Y., Kristensen, M. F., Lund, M. B., Raittio, E., Schramm, A., Meyer, R. L. & Schlafer, S. (2024). Arginine modulates the bacterial community composition and raises microscale pH in saliva-derived dental biofilms. Caries Research, 58(3). https://doi.org/10.1159/000539768

Minero, G. A. S., Larsen, P. B., Hoppe, M. E. & Meyer, R. L. (2024). Bacterial efflux pumps excrete SYTO™ dyes and lead to false-negative staining results. Analyst, 149(8), 2232-2235. https://doi.org/10.1039/d3an02112b

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Collaborations with industry

Revised 13.12.2024

Lise Refstrup Linnebjerg Pedersen