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Interdisciplinary Nanoscience Center

Publications from Nanomedicine

Publications

Wiklund, E. D., Gao, S., Hulf, T., Sibbritt, T., Nair, S., Costea, D. E., Villadsen, S. B., Bakholdt, V., Bramsen, J. B., Sorensne, J. A., Krogdahl, A., Clark, S. J. & Kjems, J. (2011). MicroRNA Alterations and Associated Aberrant DNA Methylation Patterns across Multiple Sample Types in Oral Squamous Cell Carcinoma. PLoS One, 61(1), e27840 (1-11). http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0027840

Bramsen, J. B., Pakula, M. M., Hansen, T. B., Bus, C., Langkjær, N., Odadzic, D., Smicius, R., Wengel, S. L., Chattopadhyaya, J., Engels, J. W., Herdewijn, P., Wengel, J. & Kjems, J. (2010). A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects. Nucleic Acids Research, 38(17), 5761-5773. https://doi.org/10.1093/nar/gkq341

Bramsen, J. B. & Kjems, J. (2011). Chemical modification of small interfering RNA. Methods in Molecular Biology, 721(1), 77-103. https://doi.org/10.1007/978-1-61779-037-9_5

Villadsen, S. B., Bramsen, J. B., Ostenfeld, M. S., Wiklund, E. D., Fristrup, N., Gao, S., Hansen, T. B., Jensen, T. I., Borre, M., Orntoft, T. F., Dyrskjøt, L. & Kjems, J. (2012). The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer. B J C, 106(2), 366-374. https://doi.org/10.1038/bjc.2011.520

Hansen, T. B., Kjems, J. & Bramsen, J. B. (2011). Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. RNA Biology, 8(3), 378-383.

Hansen, T. B., Wiklund, E. D., Bramsen, J. B., Villadsen, S. B., Statham, A. L., Clark, S. J. & Kjems, J. (2011). miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA. EMBO Journal, 30(21), 4414-4422. https://doi.org/10.1038/emboj.2011.359

Yu, M., Wang, J., Mura, M., Meng, Q.-Q., Xu, W., Gersen, H., Lægsgaard, E., Stensgaard, I., Kelly, R. E. A., Kjems, J., Linderoth, T. R., Kantorovich, L. N. & Besenbacher, F. (2011). Homochiral Xanthine Quintet Networks Self-Assembled on Au(111) Surfaces. ACS Nano, 5(8), 6651-6660. https://doi.org/10.1021/nn202157m

Wiklund, E. D., Bramsen, J. B., Hulf, T., Andersen, L. D., Ramanathan, R., Hansen, T. B., Villadsen, S. B., Gao, S., Ostenfeld, M. S., Borre, M., Peter, M. E., Ørntoft, T. F., Kjems, J. & Clark, S. J. (2011). Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer. International Journal of Cancer, 128(6), 1327-1334. https://doi.org/10.1002/ijc.25461

Ostenfeld, M. S., Bramsen, J. B., Lamy, P., Villadsen, S. B., Fristrup, N., Dalsgaard Sørensen, K., Ulhøi, B. P., Borre, M., Kjems, J., Andersen, L. D. & Ørntoft, T. F. (2010). miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors. Oncogene, 29(7), 1073. https://doi.org/10.1038/onc.2009.395

Sükösd, Z., Knudsen, B., Værum, M., Kjems, J. & Andersen, E. S. (2011). Multithreaded comparative RNA secondary structure prediction using stochastic context-free grammars. BMC Bioinformatics, 12(103). https://doi.org/10.1186/1471-2105-12-103

Jahn, K., Tørring, T., Voigt, N. V., Sørensen, R. S., Kodal, A. L. B., Andersen, E. S., Gothelf, K. V. & Kjems, J. (2011). Functional Patterning of DNA Origami by Parallel Enzymatic Modification. Bioconjugate Chemistry, 22(4), 819-823. https://doi.org/10.1021/bc2000098

Rahbek, U. L., Nielsen, A. F., Dong, M., You, Y., Chauchereau, A., Oupicky, D., Besenbacher, F., Kjems, J. & Howard, K. A. (2010). Bioresponsive hyperbranched polymers for siRNA and miRNA delivery. Journal of Drug Targeting, 18(10), 812-20. https://doi.org/10.3109/1061186X.2010.527982

Lützelberger, M. & Kjems, J. (2011). S1 nuclease analysis of alternatively spliced mRNA. Methods in Molecular Biology, 703, 161-71. https://doi.org/10.1007/978-1-59745-248-9_11

Mittnacht, U., Hartmann, H., Hein, S., Oliveira, H., Dong, M., Pêgo, A. P., Kjems, J., Howard, K. A. & Schlosshauer, B. (2010). Chitosan/siRNA nanoparticles biofunctionalize nerve implants and enable neurite outgrowth. Nano Letters, 10(10), 3933-9. https://doi.org/10.1021/nl1016909

Schaefer, A., Im, H.-I., Venø, M. T., Fowler, C. D., Min, A., Intrator, A., Kjems, J., Kenny, P. J., O'Carroll, D. & Greengard, P. (2010). Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. Journal of Experimental Medicine, 207(9), 1843-51. https://doi.org/10.1084/jem.20100451

Hansen, T. B., Bramsen, J. B. & Kjems, J. (2010). Re-inspection of small RNA sequence datasets reveals several novel human miRNA genes. PLoS One, 5(6), e10961. https://doi.org/10.1371/journal.pone.0010961

Beerens, N. & Kjems, J. (2010). Circularization of the HIV-1 genome facilitates strand transfer during reverse transcription. RNA, 16(6), 1226-35. https://doi.org/10.1261/rna.2039610

Jahn, K., Olsen, E. M., Nielsen, M. M., Tørring, T., Mohammadzadegan, R., Andersen, E. S., Gothelf, K. V. & Kjems, J. (2011). Site-Specific Chemical Labeling of Long RNA Molecules. Bioconjugate Chemistry, 22(1), 95-100. https://doi.org/10.1021/bc100422k

Nawroth, I., Alsner, J., Behlke, M. A., Besenbacher, F., Overgaard, J., Howard, K. A. & Kjems, J. (2010). Intraperitoneal administration of chitosan/DsiRNA nanoparticles targeting TNFα prevents radiation-induced fibrosis. Radiotherapy & Oncology, 97(1), 143-8. https://doi.org/10.1016/j.radonc.2010.09.010

Andersen, L. D., Ostenfeld, M. S., Bramsen, J. B., Silahtaroglu, A., Lamy, P., Ramanathan, R., Fristrup, N., Jensen, J. L., Andersen, C. L., Zieger, K., Kauppinen, S., Ulhøi, B. P., Kjems, J., Borre, M. & Ørntoft, T. F. (2009). Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro. Cancer Research, 69(11), 4851-60. https://doi.org/10.1158/0008-5472.CAN-08-4043

Revised 29.01.2025

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Anne Færch Nielsen