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DNA nanotechnology

DNA origami

The Kjems lab has a long history of designing and constructing functionalized self-assembled DNA and RNA nanostructures capable of complex biosensing, coupled with controlled action e.g. drug release, enzyme activation, and receptor signaling. 


Iterative selection rounds on a randomised nucleotide library allows the development of small RNA and DNA structures with high binding affinity for a specific protein of interest

Functionalisation of DNA and RNA oligos via chemical modifications