Interdisciplinary Nanoscience Center

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Publications

Professor Jørgen Kjems

Jørgen Kjems

Professor Interdisciplinary Nanoscience Center - INANO-MBG, iNANO-huset
M
H 1592, 318
P +4587155494
P +4528992086

Recent publications

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Søkilde, R., Kaadt, E., Kristensen, L. S., Venø, M. T., Kjems, J., Nyengaard, J. R., Nielsen, B. S. & Elfving, B. (2025). Application of microRNA In Situ Hybridization on Long-term Stored Human Formalin-fixed Paraffin-embedded Brain Samples from Psychiatric Patients. Molecular Neurobiology, 62(10), 12736-12746. https://doi.org/10.1007/s12035-025-05077-z
Samanta, A., Malle, M. G., Tsang, E., Omer, M., Skaanning, M. K., Kjems, J. & Gothelf, K. V. (2025). Bacteriophage-Mimetic DNA Origami Needle for Targeted Membrane Penetration and Cytosolic Cargo Delivery. bioRxiv. https://doi.org/10.1101/2025.06.16.659898
García-Rodríguez, J. L., Korsgaard, U., Vissing, S. M., Paasch, T. P., Semenova, M., Vendelbo, S. L., Jensby, E. F., Williams, H. L., Salachan, P. V., Brandt, C. B., Hanimann, J., Lin, L., Zlobec, I., Sørensen, K. D., Kjems, J., Hager, H. & Kristensen, L. S. (2025). Cancer-associated fibroblasts shape the formation of budding cancer cells at the invasive front of human colorectal cancer. Communications Biology, 8(1), Article 1345. https://doi.org/10.1038/s42003-025-08799-x
Paasch, T. P., Olesen, M. T. J., García-Rodríguez, J. L., Assmus, A. M., Fenton, R. A., Kjems, J., Hager, H. & Kristensen, L. S. (2025). ciRS-7 expression is epigenetically regulated in cancer cells across human adenocarcinomas. PLoS Genetics, 21(6), Article e1011726. https://doi.org/10.1371/journal.pgen.1011726
Kjær, M. B., Jørgensen, A. G., Fjelstrup, S., Dupont, D. M., Bus, C., Eriksen, P. L., Thomsen, K. L., Risikesan, J., Nielsen, S., Wernberg, C. W., Lauridsen, M. M., Bugianesi, E., Rosso, C., Grønbæk, H. & Kjems, J. (2025). Diagnosis and Staging of Metabolic Dysfunction-Associated Steatotic Liver Disease Using Biomarker-Directed Aptamer Panels. Biomolecules, 15(2), Article 255. https://doi.org/10.3390/biom15020255

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Professor Duncan Sutherland

Duncan Sutherland

Professor Interdisciplinary Nanoscience Center - INANO-Fysik, iNANO-huset
M
H 1592, 120
P +4587156714
P +4523385789

Recent publications

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Ayareh, Z., Moradi, M., Shafiei, M. & Sutherland, D. S. (2025). Accessible Sensing Sites in Metal–Insulator–Metal Plasmonic Nanostructure for Biosensing Applications. ACS Applied Materials and Interfaces, 17(38), 53122-53130. https://doi.org/10.1021/acsami.5c10116
Tsang, E., Scarpellini, C., Dillen, A., Jeminejs, A., Sivertsen, M. V. T., Sutherland, D. S., Lammertyn, J. & Gothelf, K. V. (2025). DNA Origami-Guided Assembly of Gold Nanoparticles for Plasmonic Enhancement in Fiber Optic Surface Plasmon Resonance Sensing. Small Methods, 9(12), Article e02111. https://doi.org/10.1002/smtd.202502111
Juul-Madsen, K., Rudolph, I. M., Gomes, J. P., Meyer, K., Ovesen, P. L., Gorniak-Walas, M., Kokoli, M., Telugu, N. S., von Tangen Sivertsen, M., Febbraro, F., Sutherland, D. S., Palmfeldt, J., Diecke, S., Andersen, O. M., Selbach, M. & Willnow, T. E. (2025). Familial Alzheimer's disease mutation identifies novel role of SORLA in release of neurotrophic exosomes. Alzheimer's and Dementia, 21(9), Article e70591. https://doi.org/10.1002/alz.70591
Gothelf, K. V., Kjems, J., Otzen, D. E., Nielsen, N. C., Hornekær, L., Zelikin, A., Pedersen, J. S., Vorup-Jensen, T. & Sutherland, D. S. (2025). Ingen reel mulighed for medarbejdere for at gøre indsigelse mod ledelsens beslutning om at afvikle iNANO. Omnibus, 2025(Juni). https://omnibus.au.dk/arkiv/vis/artikel/aabent-brev-medarbejdere-er-sat-uden-for-indflydelse-i-ledelsens-beslutning-om-at-afvikle-inano
Shahrokhtash, A., Sivertsen, M. V. T., Laursen, S. H. & Sutherland, D. S. (2025). Nanoscale Cellular Traction Force Quantification: CRISPR-Cas12a Supercharged DNA Tension Sensors in Nanoclustered Ligand Patterns. ACS applied materials & interfaces, 17(5), 7339-7352. https://doi.org/10.1021/acsami.4c18358

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Tenure-track assistant professor Julián Valero

Julián Valero Moreno

Tenure Track Assistant Professor Department of Molecular Biology and Genetics - RNA Biology and Innovation
M
H 1590, 238
P +4587150705

Recent publications

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Moradzadeh, N., Jonczyk, A., Schmitz, A., Fieberg, V., Civit, L., Valero, J., Famulok, M. & Mayer, G. (2026). Selection and Characterization of SARS-CoV-2 Spike Binding Clickmers. ChemBioChem, 27(1), Article e202500733. https://doi.org/10.1002/cbic.202500733
Städler, B., Zelikin, A. N., Valero, J., Andersen, E. S. & Sánchez, S. (2025). Artificial Biology - Assemble, Imitate, Adapt. Advanced Biology, 9(5), Article 2500236. https://doi.org/10.1002/adbi.202500236
Nielsen, J., Pedersen, J. N., Kleijwegt, G., Nowak, J. S., Nami, F., Johansen, C., Sassetti, E., Berg, B. B., Lyngsø, N. M., Brøchner, B. H., Holm Carlson, J., Simonsen, A. J., Pallisgaard Olsen, W., Simonsen, B. W., Mikkelsen, J. H., Sereika-Bejder, V., Lauritsen, J. A., Merrild, K. F., Malle, M. G. ... Otzen, D. E. (2025). Nanobodies raised against the cytotoxic α-synuclein oligomer are oligomer-specific and promote its cellular uptake. npj biosensing, 2, Article 23. https://doi.org/10.1038/s44328-025-00042-1
Mohora, I., Patiño Guillén, G., Neis, K., Valero, J., Keyser, U. F. & Bošković, F. (2025). Programmable RNA Nanostructures Enable Nanopore Detection of Cotranscriptionally Introduced RNA Modifications. Nano Letters, 25(32), 12184-12192. https://doi.org/10.1021/acs.nanolett.5c02391
Civit, L., Moradzadeh, N., Jonczyk, A., Neckermann, P., Asbach, B., Peterhoff, D., Wagner, R., Famulok, M., Mayer, G., Kjems, J. & Valero, J. (2024). A Multi-Faceted Binding Assessment of Aptamers Targeting the SARS-CoV-2 Spike Protein. International Journal of Molecular Sciences , 25(9), Article 4642. https://doi.org/10.3390/ijms25094642

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Professor Steffen Thiel

Steffen Thiel

Professor with Special Responsibilities Department of Biomedicine - Research and Education, Bartholin Building
M
H 1242, 129
P +4529270890
P +4529270890

Recent publications

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Bernth Jensen, J. M., Søgaard, O. S., Petersen, M. S., Hoffmann, S., Møller, B. K., Hansen, A. G., Sørensen, U. B. S. & Thiel, S. (2026). Isohemagglutinins exhibit synergistic polyreactivity toward Streptococcus pneumoniae surface antigens: implications for broad-spectrum reactivity of human antibodies. Medical Microbiology and Immunology, 215(1), Article 5. https://doi.org/10.1007/s00430-025-00862-y
Jensen, M., Thiel, S., Hansen, S. W. K., Palarasah, Y., Svenningsen, P. & Jensen, B. L. (2026). SGLT-2 inhibitors attenuate pattern recognition molecules collectin kidney 1 and mannose-binding lectin in kidney and liver in mice with diabetes. American journal of physiology. Renal physiology, 330(1), F17-F31. https://doi.org/10.1152/ajprenal.00184.2025
Mistegaard, C., Troldborg, A., Torgutalp, M., Loft, A. G., Thiel, S., Muche, B., Rios Rodriguez, V., Protopopov, M., Listing, J., Sieper, J., Poddubnyy, D. & Proft, F. (2025). Complement proteins in axial spondyloarthritis: associations with disease activity and TNFi treatment response in a multicentre RCT. Rheumatology Advances in Practice, 9(1), Article rkaf007. https://doi.org/10.1093/rap/rkaf007
Mistegaard, C., Troldborg, A., Torgutalp, M., Loft, A. G., Thiel, S., Muche, B., Rios Rodriguez, V., Protopopov, M., Listing, J., Sieper, J., Poddubnyy, D. & Proft, F. (2025). Complement system activation is associated with spinal radiographic progression in axial spondyloarthritis after 2 years of follow-up: findings from the CONSUL RCT. RMD Open, 11(4), Article e006087. https://doi.org/10.1136/rmdopen-2025-006087
Hymøller, K. M., Crone, L., Thiel, S. & Hennet, T. (2025). Differential Recognition of Lipopolysaccharide O-Antigens by the Pattern Recognition Molecules Mannan-Binding Lectin and Ficolins of the Complement System. Journal of Innate Immunity, 17(1), 397–413. https://doi.org/10.1159/000547441

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Professor Søren Degn

Søren Egedal Degn

Associate Professor Department of Biomedicine - Forskning og uddannelse, Skou-bygningen
M
H 1116, 356
P +4522141703
P +4522141703

Recent publications

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Pilati, D., Agyei, E. K., Elkhashab, M., Fuchs, E., Nielsen, I. H., Bjerg, T. W., Anthi, A. K., Jiménez-Reinoso, A., Iversen, M. B., Pohl, L., Narita, R., Frago, S., Jakobsen, M. R., Andersen, J. T., Degn, S. E., Paludan, S. R., Alvarez-Vallina, L. & Howard, K. A. (2025). Exploiting FcRn engagement of an albumin-CpG oligonucleotide covalent conjugate for potent TLR9 immune induction. Journal of Biological Chemistry, 301(6), Article 108508. https://doi.org/10.1016/j.jbc.2025.108508
Rasmussen, M. Q., Bønnelykke-Behrndtz, M. L., Merrild, C., Tvilling, I. K. S., Christensen, J. N., Nielsen, M. M., Georgsen, J. B., Naumann, N., Gudbergsson, J. M., Etzerodt, A., Pedersen, J. S., Jenkins, R. W., Degn, S. E., Moestrup, S. K., Schmidt, H., Steiniche, T. & Madsen, M. (2025). LRP2 Expression in Melanoma Is Associated With a Transitory Cell State, Increased T Cell Infiltration, and Is Upregulated by IFNy Signaling. Pigment Cell & Melanoma Research, 38(5), Article e70053. https://doi.org/10.1111/pcmr.70053
Fonager, S. V., Winther, G., Weber, Y. C. L., Wittenborn, T. R., Kastberg, K. S., Terczyńska-Dyla, E., Jensen, L., Hansen, L. A., Carroll, M. C., Luo, Y., Lin, L. & Degn, S. E. (2025). Maternal imprinting of autoreactivity in a murine model of systemic lupus erythematosus. Brain, Behavior, and Immunity, 129, 921-934. https://doi.org/10.1016/j.bbi.2025.07.025
Rovsing, A. B., Green, K., Jensen, L., Nielsen, I. H., Mikkelsen, J. G. & Degn, S. E. (2025). Multiparametric Optimization of Human Primary B-Cell Cultures Using Design of Experiments. Scandinavian Journal of Immunology, 102(2), Article e70043. https://doi.org/10.1111/sji.70043
Degn, S. E. & Tolar, P. (2025). Towards a unifying model for B-cell receptor triggering. Nature Reviews Immunology, 25(2), 77-91. Article 976. https://doi.org/10.1038/s41577-024-01073-x

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Professor Fiona Watt

Professor Dr. Ralf Jungmann

Revised 08.12.2025
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Anne Færch Nielsen