Bernth Jensen, J. M., Hansen, A. T., Söderström, A., Jørgensen, C. S., Larsen, C. S., Skov Sørensen, U. B., Thiel, S. & Petersen, M. S. (2022). A low level of naturally occurring antibodies associates with functional antibody deficiency. Clinical Immunology, 241, [109070]. https://doi.org/10.1016/j.clim.2022.109070

Elbæk Mistegård, C., Jensen, L., Christiansen, M., Bjerre, M., Jensen, J. M. B. & Thiel, S. (2022). Low levels of the innate immune system proteins MASP-2 and MAp44 in patients with common variable immunodeficiency. Scand. J. Immunol.

Brix, N., Glerup, M., Thiel, S., Mistegaard, C. E., Skals, R. G., Berntson, L., Fasth, A., Nielsen, S. M., Nordal, E., Rygg, M., Hasle, H., Albertsen, B. K., Herlin, T. & Nordic Study Group of Pediatric Rheumatology (NoSPeR) group (2022). M-ficolin: a valuable biomarker to identify leukaemia from juvenile idiopathic arthritis. Archives of Disease in Childhood, 107(4), 371-376. https://doi.org/10.1136/archdischild-2021-322114

Schack, V. R., Herlin, M. K., Pedersen, H., Jensen, J. M. B., Faerch, M., Bundgaard, B., Jensen, R. K., Jensen, U. B., Christensen, R., Andersen, G. R., Thiel, S. & Höllsberg, P. (2022). Novel homozygous CD46 variant with C-isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome. European Journal of Immunology. https://doi.org/10.1002/eji.202249838

Palarasah, Y., Henriksen, A. S. L., Thiel, S., Henriksen, M. & Hansen, S. W. K. (2022). Potency measurements of the complement system facilitated by antibodies targeting the zymogen form of complement factor D (Adipsin). Molecular immunology, 146, 46-49. https://doi.org/10.1016/j.molimm.2022.04.002

Henriksen, M. L., Nielsen, C., Pedersen, D., Andersen, G. R., Thiel, S., Palarasah, Y. & Hansen, S. W. K. (2022). Quantification of the pro-form of human complement component factor D (adipsin). Journal of Immunological Methods, 507, 113295. https://doi.org/10.1016/j.jim.2022.113295

Pedersen, H., Jensen, R. K., Hansen, A. G., Petersen, S. V., Thiel, S., Laursen, N. S. & Andersen, G. R. (2022). Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity. Frontiers in Immunology, 13, 872536. https://doi.org/10.3389/fimmu.2022.872536

Gregersen, E., Betzer, C., Kim, W. S., Kovacs, G., Reimer, L., Halliday, G. M., Thiel, S. & Jensen, P. H. (2021). Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity. Journal of Neuroinflammation, 18, [177]. https://doi.org/10.1186/s12974-021-02225-9

Juul-Madsen, K., Troldborg, A., Wittenborn, T. R., Axelsen, M. G., Zhao, H., Klausen, L. H., Luecke, S., Paludan, S. R., Stengaard-Pedersen, K., Dong, M., Møller, H. J., Thiel, S., Jensen, H., Schuck, P., Sutherland, D. S., Degn, S. E. & Vorup-Jensen, T. (2021). Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus. Proceedings of the National Academy of Sciences of the United States of America, 118(30), [e2106647118]. https://doi.org/10.1073/pnas.2106647118

Hoffmann-Petersen, I. T., Holt, C. B., Jensen, L., Hage, C., Mellbin, L. G., Thiel, S., Hansen, T. K. & Østergaard, J. A. (2021). Effect of dipeptidyl peptidase-4 inhibitors on complement activation. Diabetes/Metabolism Research and Reviews, 37(3), [e3385]. https://doi.org/10.1002/dmrr.3385

Boldt, A. B. W., Oliveira-Toré, C. D. F., Kretzschmar, G. C., Weinschutz Mendes, H., Stinghen, S. T., Andrade, F. A., Bumiller-Bini, V., Gonçalves, L. B., Braga, A. C. D. M., Stahlke, E. V. R. S., Velavan, T. P., Thiel, S. & de Messias-Reason, I. J. T. (2021). Hepatitis B Virus Infection Among Leprosy Patients: A Case for Polymorphisms Compromising Activation of the Lectin Pathway and Complement Receptors. Frontiers in Immunology, 11, [574457]. https://doi.org/10.3389/fimmu.2020.574457

Pihl, R., Jensen, R. K., Poulsen, E. C., Jensen, L., Hansen, A. G., Thøgersen, I. B., Dobó, J., Gál, P., Andersen, G. R., Enghild, J. J. & Thiel, S. (2021). ITIH4 acts as a protease inhibitor by a novel inhibitory mechanism. Science Advances, 7(2), [7381]. https://doi.org/10.1126/sciadv.aba7381

Gedebjerg, A., Thomsen, R. W., Kjaergaard, A. D., Steffensen, R., Nielsen, J. S., Rungby, J., Friborg, S. G., Brandslund, I., Thiel, S., Beck-Nielsen, H., Sørensen, H. T., Hansen, T. K. & Bjerre, M. (2021). Mannose-binding lectin and risk of infections in type 2 diabetes: A Danish cohort study. Journal of Diabetes and its Complications, 35(5), [107873]. https://doi.org/10.1016/j.jdiacomp.2021.107873

Medjeral-Thomas, N. R., Troldborg, A., Hansen, A. G., Gisby, J., Clarke, C., Prendecki, M., McAdoo, S. P., Sandhu, E., Lightstone, L., Thomas, D. C., Willicombe, M., Botto, M., Peters, J. E., Pickering, M. C. & Thiel, S. (2021). Plasma Lectin Pathway Complement Proteins in Patients With COVID-19 and Renal Disease. Frontiers in Immunology, 12, [671052]. https://doi.org/10.3389/fimmu.2021.671052

Medjeral-Thomas, N. R., Troldborg, A., Hansen, A. G., Pihl, R., Clarke, C. L., Peters, J. E., Thomas, D. C., Willicombe, M., Palarasah, Y., Botto, M., Pickering, M. C. & Thiel, S. (2021). Protease inhibitor plasma concentrations associate with COVID-19 infection. Oxford open immunology, 2(1), [iqab014]. https://doi.org/10.1093/oxfimm/iqab014

Demir, F., Troldborg, A., Thiel, S., Lassé, M., Huesgen, P. F., Tomas, N. M., Wiech, T. & Rinschen, M. M. (2021). Proteolysis and inflammation of the kidney glomerulus. Cell and Tissue Research, 385(2), 489-500. https://doi.org/10.1007/s00441-021-03433-8

Bernth Jensen, J. M., Skeldal, S., Petersen, M. S., Møller, B. K., Hoffmann, S., Jensenius, J. C., Sørensen, U. B. S. & Thiel, S. (2021). The human natural anti-αGal antibody targets common pathogens by broad-spectrum polyreactivity. Immunology, 162(4), 434-451. https://doi.org/10.1111/imm.13297

Bernth Jensen, J. M., Søgaard, O. S. & Thiel, S. (2021). The level of naturally occurring anti-αGal antibody predicts antibody response to polysaccharide vaccination in HIV-infected adults. Scandinavian Journal of Immunology, 93(5), [e13008]. https://doi.org/10.1111/sji.13008

Østergaard, J. A., Jansson Sigfrids, F., Forsblom, C., Dahlström, E. H., Thorn, L. M., Harjutsalo, V., Flyvbjerg, A., Thiel, S., Hansen, T. K. & Groop, P-H. (2021). The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes. Scientific Reports, 11(1), [8919]. https://doi.org/10.1038/s41598-021-88352-y

Pedersen, H., Jensen, R. K., Hansen, A. G., Gadeberg, T. A. F., Thiel, S., Laursen, N. S. & Andersen, G. (2020). A C3 specific nanobody that blocks all three activation pathways in the human and murine complement system. The Journal of Biological Chemistry, 295(26), 8746-8758. https://doi.org/10.1074/jbc.RA119.012339

Pedersen, H., Jensen, R. K., Jensen, J. M. B., Fox, R., Pedersen, D. V., Olesen, H. G., Hansen, A. G., Christiansen, D., Mazarakis, S. M. M., Lojek, N., Hansen, P., Gadeberg, T. A. F., Zarantonello, A., Laursen, N. S., Mollnes, T. E., Johnson, M. B., Stevens, B., Thiel, S. & Andersen, G. R. (2020). A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity. Journal of Immunology, 205(8). https://doi.org/10.4049/jimmunol.2000752

Bernth Jensen, J. M., Petersen, M. S., Ellerman-Eriksen, S., Møller, B. K., Jensenius, J. C., Sørensen, U. B. S. & Thiel, S. (2020). Abundant human anti-Galα3Gal antibodies display broad pathogen reactivity. Scientific Reports, 10(1), [4611]. https://doi.org/10.1038/s41598-020-61632-9

Weinschutz Mendes, H., Boldt, A. W., Stahlke, E., Jensenius, J. C., Thiel, S. & Messias-Reason, I. J. T. (2020). Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels. PLOS Neglected Tropical Diseases , 14(4), [e0007534]. https://doi.org/10.1371/journal.pntd.0007534

Zarantonello, A., Presumey, J., Simoni, L., Yalcin, E., Fox, R., Hansen, A., Olesen, H. G., Thiel, S., Johnson, M. B., Stevens, B., Laursen, N. S., Carroll, M. C. & Andersen, G. R. (2020). An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase. Journal of Immunology, 205(6), 1678-1694. https://doi.org/10.4049/jimmunol.2000528

Holt, C. B., Hoffmann-Petersen, I. T., Hansen, T. K., Parving, H-H., Thiel, S., Hovind, P., Tarnow, L., Rossing, P. & Østergaard, J. A. (2020). Association between severe diabetic retinopathy and lectin pathway proteins - an 18-year follow-up study with newly diagnosed type 1 diabetes patients. Immunobiology, 225(3), [151939]. https://doi.org/10.1016/j.imbio.2020.151939

Jensen, E. G., Jakobsen, T. S., Thiel, S., Askou, A. L. & Corydon, T. J. (2020). Associations between the Complement System and Choroidal Neovascularization in Wet Age-Related Macular Degeneration. International Journal of Molecular Sciences , 21(24), [9752]. https://doi.org/10.3390/ijms21249752

Świerzko, A. S., Michalski, M., Sokołowska, A., Nowicki, M., Szala-Poździej, A., Eppa, Ł., Mitrus, I., Szmigielska-Kapłon, A., Sobczyk-Kruszelnicka, M., Michalak, K., Gołos, A., Wierzbowska, A., Giebel, S., Jamroziak, K., Kowalski, M. L., Brzezińska, O., Thiel, S., Matsushita, M., Jensenius, J. C. ... Cedzyński, M. (2020). Associations of Ficolins With Hematological Malignancies in Patients Receiving High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantations. Frontiers in Immunology, 10, [3097]. https://doi.org/10.3389/fimmu.2019.03097

Sokołowska, A., Świerzko, A. S., Gajek, G., Gołos, A., Michalski, M., Nowicki, M., Szala-Poździej, A., Wolska-Washer, A., Brzezińska, O., Wierzbowska, A., Jamroziak, K., Kowalski, M. L., Thiel, S., Matsushita, M., Jensenius, J. C. & Cedzyński, M. (2020). Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults. Scientific Reports, 10, [10561]. https://doi.org/10.1038/s41598-020-67516-2

LaFon, D. C., Thiel, S., Kim, Y-I., Dransfield, M. T. & Nahm, M. H. (2020). Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults. Immunity & ageing : I & A, 17, [18]. https://doi.org/10.1186/s12979-020-00189-7

Halkjær, L., Troldborg, A., Pedersen, H., Jensen, L., Hansen, A. G., Krarup Hansen, T., Bjerre, M., Østergaard, J. A. & Thiel, S. (2020). Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-level in Plasma Samples from Mice and Humans. Frontiers in Immunology, 11, [774]. https://doi.org/10.3389/fimmu.2020.00774

Bernth Jensen, J. M., Laursen, N. S., Kjeldsen Jensen, R., Andersen, G. R., Jensenius, J. C., Skov Sørensen, U. B. & Thiel, S. (2020). Complement activation by human IgG antibodies to galactose-α-1,3-galactose. Immunology, 161(1), 66-79. https://doi.org/10.1111/imm.13229

Troldborg, A., Halkjær, L., Pedersen, H., Hansen, A., Loft, A. G., Lindegaard, H., Stengaard-Pedersen, K., Graversen, J. H., Palarasah, Y. & Thiel, S. (2020). Complement activation in human autoimmune diseases and mouse models; employing a sandwich immunoassay specific for C3dg. Journal of Immunological Methods, 486, [112866]. https://doi.org/10.1016/j.jim.2020.112866

Laursen, N. S., Pedersen, D. V., Gytz, H., Zarantonello, A., Bernth Jensen, J. M., Hansen, A. G., Thiel, S. & Andersen, G. R. (2020). Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System. Frontiers in Immunology, 11, [1504]. https://doi.org/10.3389/fimmu.2020.01504

Holers, V. M., Borodovsky, A., Scheinman, R. I., Ho, N., Ramirez, J. R., Dobó, J., Gál, P., Lindenberger, J., Hansen, A. G., Desai, D., Pihl, R., Thiel, S. & Banda, N. K. (2020). Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D. Frontiers in Immunology, 11, [201]. https://doi.org/10.3389/fimmu.2020.00201

Gedebjerg, A., Bjerre, M., Kjaergaard, A. D., Steffensen, R., Nielsen, J. S., Rungby, J., Friborg, S. G., Brandslund, I., Thiel, S., Beck-Nielsen, H., Sørensen, H. T., Hansen, T. K. & Thomsen, R. W. (2020). Mannose-Binding Lectin and Risk of Cardiovascular Events and Mortality in Type 2 Diabetes: A Danish Cohort Study. Diabetes Care, 43(9), 2190-2198. https://doi.org/10.2337/dc20-0345

Troldborg, A., Thiel, S., Elbaek, C. M., Hansen, A., Korsholm, T-L., Stengaard-Pedersen, K. & Loft, A. G. (2020). Plasma levels of H- and L-ficolin are increased in axial spondyloarthritis: Improvement of disease identification. Clinical and Experimental Immunology, 199(1), 79-87. https://doi.org/10.1111/cei.13374

Anker-Møller, T., Hvas, A-M., Sunde, N., Thiel, S. & Troldborg, A. (2020). Proteins of the Lectin Pathway of complement activation at the site of injury in subarachnoid hemorrhage compared with peripheral blood. Brain and Behavior, 10(8), e01728. [01728]. https://doi.org/10.1002/brb3.1728

Pedersen, D. V., Rösner, T., Hansen, A. G., Andersen, K. R., Thiel, S., Andersen, G. R., Valerius, T. & Laursen, N. S. (2020). Recruitment of properdin by bi-specific nanobodies activates the alternative pathway of complement. Molecular Immunology, 124, 200-210. https://doi.org/10.1016/j.molimm.2020.06.005

Frederiksen, K., Krag, A. E., Larsen, J. B., Kiil, B. J., Thiel, S. & Hvas, A-M. (2020). Remote ischemic preconditioning does not influence lectin pathway protein levels in head and neck cancer patients undergoing surgery. PLOS ONE, 15(4), [e0230411]. https://doi.org/10.1371/journal.pone.0230411

Sokołowska, A., Świerzko, A. S., Szala-Poździej, A., Augustynowicz-Kopeć, E., Kozińska, M., Niemiec, T., Błachnio, M., Borkowska-Tatar, D., Jensenius, J. C., Thiel, S., Dziadek, J. & Cedzyński, M. (2020). Selected factors of the innate immunity in Polish patients suffering from pulmonary tuberculosis. Immunobiology, 225(3), 151905. [151905]. https://doi.org/10.1016/j.imbio.2020.151905

Bro-Jeppesen, J., Jeppesen, A. N., Haugaard, S., Troldborg, A., Hassager, C., Kjaergaard, J., Kirkegaard, H., Wanscher, M., Hvas, A-M. & Thiel, S. (2020). The complement lectin pathway protein MAp19 and out-of-hospital cardiac arrest: Insights from two randomized clinical trials. European Heart Journal: Acute Cardiovascular Care, 9(4_Suppl), S145-S152. https://doi.org/10.1177/2048872619870031

Jensen, J. M. B., Møller, B. K., Thiel, S. & Hansen, A. T. (2019). Antibody Dependent Enhancement of Infections after High Dose Chemotherapy. Blood, 134(Supplement 1), 1047. https://doi.org/10.1182/blood-2019-122236

Sandgaard, E., Troldborg, A., Lauridsen, S. V., Gyldenholm, T., Thiel, S. & Hvas, A-M. (2019). Changes in the Lectin Pathway Following Intracerebral or Spontaneous Subarachnoid Hemorrhage. Molecular Neurobiology, 56(1), 78-87. https://doi.org/10.1007/s12035-018-1066-0

Brinck Holt, C., Østergaard, J. A., Thiel, S., Hansen, T. K., Mellbin, L., Sörensson, P. & Bjerre, M. (2019). Circulating lectin pathway proteins do not predict short-term cardiac outcomes after myocardial infarction. Clinical and Experimental Immunology, 198(1), 94-100. https://doi.org/10.1111/cei.13315

Troldborg, A., Voss, A., Hansen, S. W. K., Jensenius, J. C., Stengaard-Pedersen, K. & Thiel, S. (2019). Complement Protein CL-K1 at High Concentrations Protects Against the Development of Lupus Nephritis. Arthritis & Rheumatology, 71(suppl.10), [2895]. https://acrabstracts.org/abstract/complement-protein-cl-k1-at-high-concentrations-protects-against-the-development-of-lupus-nephritis/

Glerup, M., Thiel, S., Rypdal, V., Arnstad, E. D., Ekelund, M., Peltoniemi, S., Aalto, K., Rygg, M., Nielsen, S., Fasth, A., Berntson, L., Nordal, E. & Herlin, T. (2019). Complement lectin pathway protein levels reflect disease activity in juvenile idiopathic arthritis: A longitudinal study of the Nordic JIA cohort. Pediatric Rheumatology , 17(1), [63]. https://doi.org/10.1186/s12969-019-0367-9

Pryds, K., Schmidt, M. R., Bjerre, M., Thiel, S., Refsgaard, J., Bøtker, H. E., Østgård, R. D. & Nielsen, R. R. (2019). Effect of long-term remote ischemic conditioning on inflammation and cardiac remodeling. Scandinavian Cardiovascular Journal, 53(4), 183-191. https://doi.org/10.1080/14017431.2019.1622770

Michalski, M., Pągowska-Klimek, I., Thiel, S., Świerzko, A. S., Hansen, A. G., Jensenius, J. C. & Cedzyński, M. (2019). Factors involved in initiation and regulation of complement lectin pathway influence postoperative outcome after pediatric cardiac surgery involving cardiopulmonary bypass. Scientific Reports, 9, [2930]. https://doi.org/10.1038/s41598-019-39742-w

Troldborg, A., Steffensen, R., Trendelenburg, M., Hauser, T., Winther, K. G., Hansen, A. G., Stengaard-Pedersen, K., Voss, A. & Thiel, S. (2019). Ficolin-3 Deficiency Is Associated with Disease and an Increased Risk of Systemic Lupus Erythematosus. Journal of Clinical Immunology, 39(4), 421-429. https://doi.org/10.1007/s10875-019-00627-2

Larsen, J. B., Andersen, A. S., Hvas, C. L., Thiel, S., Lassen, M. R., Hvas, A-M. & Hansen, A. T. (2019). Lectin pathway proteins of the complement system in normotensive pregnancy and pre-eclampsia. American Journal of Reproductive Immunology Online, 81(4), e13092. [e13092]. https://doi.org/10.1111/aji.13092