STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Teillet, F., Lacroix, M., Thiel, S., Weilguny, D., Agger, T., Arlaud, G. J. & Thielens, N. M. (2007). Identification of the site of human mannan-binding lectin involved in the interaction with its partner serine proteases: the essential role of Lys55. Journal of Immunology, 178(9), 5710-6.

Tang, C., Kwiatkowski, D., Garred, P., Madsen, H. O., Svejgaard, A., Michaelsen, T. E., Hibberd, M. L., Sumiya, M., Summerfield, J. A., Booy, R., Levin, M., Van Helden, P., Hoal-van Helden, E., Kuijper, E. J., Fijen, C. A., Dankert, J., Thiel, S., Megyeri, P., Deli, M. A. & Abraham, C. S. (1999). Mannose-binding lectin and meningococcal disease (multiple letters) [3]. Lancet, 354(9175), 336-338. https://doi.org/10.1016/S0140-6736(05)75240-5

Tan, S. M., Chung, M. C., Kon, O. L., Thiel, S., Lee, S. H. & Lu, J. (1996). Improvements on the purification of mannan-binding lectin and demonstration of its Ca(2+)-independent association with a C1s-like serine protease. Biochemical Journal, 319 ( Pt 2), 329-32.

Takahashi, K., Gordon, J., Liu, H., Sastry, K. N., Epstein, J. E., Motwani, M., Laursen, I., Thiel, S., Jensenius, J. C., Carroll, M. & Ezekowitz, R. A. (2002). Lack of mannose-binding lectin-A enhances survival in a mouse model of acute septic periotonitis. Microbes and Infections, 4, 773-784.

Takahashi, K., Gordon, J., Liu, H., Sastry, K. N., Epstein, J. E., Motwani, M., Laursen, I., Thiel, S., Jensenius, J. C., Carroll, M. & Ezekowitz, R. A. B. (2002). Lack of mannose-binding lectin-A enhances survival in a mouse model of acute septic peritonitis. Microbes and Infection, 4(8), 773-84.

Displaying results 86 to 90 out of 500

Full list of publications

Group leader

Steffen Thiel

Professor with Special Responsibilities Department of Biomedicine - Forskning og uddannelse, Skou-bygningen

M st@biomed.au.dk
H 1115, 232
P +4587167853
P +4529270890

Group members

Postal Address

Interdisciplinary Nanoscience Center (iNANO)

Gustav Wieds Vej 14

8000 Aarhus C

Denmark

Revised 17.04.2023

Rikke Ploug Frydenberg