Interdisciplinary Nanoscience Center

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 CellPAT STEFFEN THIEL: Innate Immune system

STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Isayeva, G., Rumora, K., Potlukova, E., Leibfarth, J.-P., Schäfer, I., Bartha, Z., Zellweger, M. J., Trendelenburg, M., Hejlesen, T. K., Hansen, A. G., Thiel, S. & Mueller, C. (2024). Diagnostic and prognostic value of mannan-binding lectin associated protein (MAp19) for functionally relevant coronary artery disease. Clinica Chimica Acta, 558, Article 119668. https://doi.org/10.1016/j.cca.2024.119668
Jensen, M., Eickhoff, M. K., Persson, F., Rossing, P., Thiel, S., Hansen, S. W. K., Palarasah, Y., Svenningsen, P. & Jensen, B. L. (2024). Effect of dapagliflozin on collectins and complement activation in plasma from patients with type 2 diabetes and albuminuria: Data from the DapKid cohort. Immunobiology, 229(3), 152797. Article 152797. https://doi.org/10.1016/j.imbio.2024.152797
Mistegård, C. E., Troldborg, A., Loft, A. G., Thiel, S., Spiller, L., Protopopov, M., Rios Rodriguez, V., Muche, B., Rademacher, J., Weber, A. K., Lüders, S., Sieper, J., Poddubnyy, D. & Proft, F. (2024). Exploring complement biomarkers in suspected axial spondyloarthritis. RMD Open, 10(2), Article e004127. https://doi.org/10.1136/rmdopen-2024-004127
Troldborg, A., Godnic-Polai, Z., Cervenak, L., Hansen, A. G., Farkas, H. & Thiel, S. (2024). Inter-α-trypsin inhibitor heavy chain 4 (ITIH4) as a compensatory protease inhibitor in hereditary angioedema. The Journal of Allergy and Clinical Immunology, 154(2), 468-479.e6. https://doi.org/10.1016/j.jaci.2024.03.028
Mikkelsen, J. H., Stødkilde, K., Jensen, M. P., Hansen, A. G., Wu, Q., Lorentzen, J., Graversen, J. H., Andersen, G. R., Fenton, R. A., Etzerodt, A., Thiel, S. & Andersen, C. B. F. (2024). Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis. Journal of Immunology, 212(8), 1334-1344. https://doi.org/10.4049/jimmunol.2300862

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Group leader

Postal Address

Interdisciplinary Nanoscience Center (iNANO)

Gustav Wieds Vej 14

8000 Aarhus C

Denmark
Revised 08.12.2025
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Rikke Ploug Frydenberg