Sandahl, T. D., Kelsen, J., Dige, A., Dahlerup, J. F., Agnholt, J., Hvas, C. L. & Thiel, S. (2014).
The lectin pathway of the complement system is downregulated in Crohn's disease patients who respond to anti-TNF-α therapy.
Journal of Crohn's & Colitis,
8(6), 521-8.
https://doi.org/10.1016/j.crohns.2013.11.007
Ammitzbøll, C. G., Thiel, S., Jensenius, J. C., Ellingsen, T., Hørslev-Petersen, K., Hetland, M. L., Junker, M. P., Krogh, N. S., Ostergaard, M.
& Stengaard-Pedersen, K. (2013).
Brief report: m-ficolin levels reflect disease activity and predict remission in early rheumatoid arthritis.
Arthritis & Rheumatism,
65(12), 3045-50.
https://doi.org/10.1002/art.38179
Degn, S. E., Jensen, L., Olszowski, T.
, Jensenius, J. C. & Thiel, S. (2013).
Co-complexes of MASP-1 and MASP-2 associated with the soluble pattern-recognition molecules drive lectin pathway activation in a manner inhibitable by MAp44.
Journal of Immunology,
191(3), 1334-45.
https://doi.org/10.4049/jimmunol.1300780
Østergaard, J., Bjerre, M., Dagnaes-Hansen, F.
, Hansen, T. K., Thiel, S. & Flyvbjerg, A. (2013).
Diabetes-induced changes in mannan-binding lectin levels and complement activation in a mouse model of type 1 diabetes.
Scandinavian Journal of Immunology,
77(3), 187-94.
https://doi.org/10.1111/sji.12027
Axelgaard, E., Jensen, L., Dyrlund, T. F., Nielsen, H. J.
, Enghild, J. J., Thiel, S. & Jensenius, J. C. (2013).
Investigations on Collectin Liver 1.
Journal of Biological Chemistry,
288(32), 23407-23420.
https://doi.org/10.1074/jbc.M113.492603
Ingels, C., Vanhorebeek, I., Steffensen, R., Derese, I.
, Jensen, L., Wouters, P. J., Hermans, G.
, Thiel, S. & Van den Berghe, G. (2013).
Lectin pathway of complement activation and relation with clinical complications in critically ill children.
Pediatric Research.
https://doi.org/10.1038/pr.2013.180
Boldt, A. B. W., Goeldner, I., Stahlke, E. R. S.
, Thiel, S., Jensenius, J. C. & de Messias-Reason, I. J. T. (2013).
Leprosy association with low MASP-2 levels generated by MASP2 haplotypes and polymorphisms flanking MAp19 exon 5.
PLOS ONE,
8(7), e69054.
https://doi.org/10.1371/journal.pone.0069054
Egli, A., Schäfer, J., Osthoff, M.
, Thiel, S., Mikkelsen, C., Rauch, A., Hirsch, H. H., Bucher, H. C., Young, J.
, Jensenius, J. C., Battegay, M., Trendelenburg, M. & Swiss HIV Cohort Study (2013).
Low Levels of Mannan-Binding Lectin or Ficolins Are Not Associated with an Increased Risk of Cytomegalovirus Disease in HIV-Infected Patients.
P L o S One,
8(1), e51983.
https://doi.org/10.1371/journal.pone.0051983
Kjaer, T. R., Hansen, A. G., Sørensen, U. B. S., Holm, A. T., Sørensen, G. L.
, Jensenius, J. C. & Thiel, S. (2013).
M-ficolin binds selectively to the capsular polysaccharides of Streptococcus pneumoniae serotypes 19B and 19C and of a Streptococcus mitis strain.
Infection and Immunity,
81(11).
https://doi.org/10.1128/IAI.00720-13
Brinkmann, C. R.
, Jensen, L., Dagnaes-Hansen, F., Holm, I. E., Endo, Y., Fujita, T.
, Thiel, S., Jensenius, J. C. & Degn, S. E. (2013).
Mitochondria and the lectin pathway of complement.
Journal of Biological Chemistry.
https://doi.org/10.1074/jbc.M112.430249
Joseph, K., Kulik, L., Coughlin, B., Kunchithapautham, K., Bandyopadhyay, M.
, Thiel, S., Thielens, N. M., Holers, V. M. & Rohrer, B. (2013).
Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner.
Journal of Biological Chemistry,
288(18), 12753-65.
https://doi.org/10.1074/jbc.M112.421891
Frauenknecht, V.
, Thiel, S., Storm, L., Meier, N., Arnold, M., Schmid, J.-P., Saner, H. & Schroeder, V. (2013).
Plasma levels of mannan-binding lectin (MBL)-associated serine proteases (MASPs) and MBL-associated protein in cardio- and cerebrovascular diseases.
Clinical and Experimental Immunology,
173(1), 112-20.
https://doi.org/10.1111/cei.12093
Gytz Ammitzbøll, C., Steffensen, R., Jørgen Nielsen, H.
, Thiel, S., Stengaard-Pedersen, K., Bøgsted, M.
& Jensenius, J. C. (2013).
Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44.
PLOS ONE,
8(9), e73317.
https://doi.org/10.1371/journal.pone.0073317
Boldt, A. B. W., Sanchez, M. I. N., Stahlke, E. R. S., Steffensen, R.
, Thiel, S., Jensenius, J. C., Prevedello, F. C., Mira, M. T., Kun, J. F. J. & Messias-Reason, I. J. T. (2013).
Susceptibility to Leprosy is Associated with M-ficolin Polymorphisms.
Journal of Clinical Immunology,
33(1), 210-9.
https://doi.org/10.1007/s10875-012-9770-4
Petersen, T.
, Møller-Larsen, A., Ellermann-Eriksen, S., Thiel, S. & Christensen, T. (2012).
Effects of interferon-beta therapy on elements in the antiviral immune response towards the human herpesviruses EBV, HSV, and VZV, and to the human endogenous retroviruses HERV-H and HERV-W in multiple sclerosis. Journal of Neuroimmunology,
249(1-2), 105-108.
http://www.ncbi.nlm.nih.gov/pubmed/22608883
Schlapbach, L. J., Woerner, A.
, Thiel, S., Ammann, R. A., Aebi, C., Nelle, M.
& Jensenius, J. C. (2012).
Good agreement between capillary and venous sampling for lectin pathway proteins.
Immunobiology.
https://doi.org/10.1016/j.imbio.2012.06.001
Verma, A., White, M., Vathipadiekal, V., Tripathi, S., Mbianda, J., Ieong, M., Qi, L., Taubenberger, J. K., Takahashi, K.
, Jensenius, J. C., Thiel, S. & Hartshorn, K. L. (2012).
Human H-ficolin inhibits replication of seasonal and pandemic influenza A viruses.
Journal of Immunology,
189(5), 2478-87.
https://doi.org/10.4049/jimmunol.1103786
Sandahl, T. D., Agnholt, J., Møller, H. J., Hamilton-Dutoit, S. J., Grønbæk, H., Thiel, S. & Vilstrup, H. (2012).
Kupffer cells exhibit strong inflammatory activation in alcoholic hepatitis: Kupffer cells exhibit strong inflammatory activation in alcoholic hepatitis.
Sandahl, T. D., Agnholt, J., Møller, H. J., Hamilton-Dutoit, S. J., Grønbæk, H., Thiel, S. & Vilstrup, H. (2012).
Kupffer cells exhibit strong inflammatory activation in alcoholic hepatitis: Kupffer cells exhibit strong inflammatory activation in alcoholic hepatitis.
Journal of Hepatology. Supplement,
56(1697), 982a-982a. Article 1697.
Degn, S. E., Jensen, L., Hansen, A. G., Duman, D., Tekin, M.
, Jensenius, J. C. & Thiel, S. (2012).
Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function.
Journal of Immunology,
189(8), 3957-69.
https://doi.org/10.4049/jimmunol.1201736
Østergaard, J. A., Bjerre, M., RamachandraRao, S. P., Sharma, A. K.
, Nyengaard, J. R., Hansen, T. K., Thiel, S. & Flyvbjerg, A. (2012).
Mannan-binding lectin in diabetic kidney disease: the impact of mouse genetics in a type 1 diabetes model.
Experimental Diabetes Research,
2012, 678381.
https://doi.org/10.1155/2012/678381
Thiel, S., Jensen, L., Degn, S. E., Nielsen, H. J., Gál, P., Dobó, J.
& Jensenius, J. C. (2012).
Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components.
Clinical and Experimental Immunology. Supplement,
169(1), 38-48.
https://doi.org/10.1111/j.1365-2249.2012.04584.x
Grönwall, C., Chen, Y., Vas, J., Khanna, S.
, Thiel, S., Corr, M., Kono, D. H. & Silverman, G. J. (2012).
MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses.
PNAS (Proceedings of the National Academy of Sciences of the United States of America),
109(48), 19745-50.
https://doi.org/10.1073/pnas.1211868109
Foldager, L., Steffensen, R. N.
, Thiel, S., Als, T. D., Nielsen, H. J., Nordentoft, M.
, Mortensen, P. B., Mors, O. & Jensenius, J. C. (2012).
MBL and MASP-2 concentrations in serum and MBL2 promoter polymorphisms are associated to schizophrenia.
Acta Neuropsychiatrica,
24(4), 199-207.
https://doi.org/10.1111/j.1601-5215.2011.00618.x
Kjær, T. R., Hansen, A. G., Sørensen, U. B. S., Holm, A. T., Sørensen, G. L.
, Jensenius, J. C. & Thiel, S. (2012).
M-ficolin binds selectively to the capsular polysaccharides of Streptococcus pneumoniae serotypes 19B and 19C and of a S. mitis strain.
Infection and Immunity.
https://doi.org/10.1128/IAI.01148-12
Schlapbach, L. J.
, Kjær, T. R., Thiel, S., Mattmann, M., Nelle, M., Wagner, B. P., Ammann, R. A., Aebi, C.
& Jensenius, J. C. (2012).
M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis.
Pediatric Research,
71(4 Pt 1), 368-74.
https://doi.org/10.1038/pr.2011.71
Ameye, L., Paesmans, M.
, Thiel, S., Jensenius, J. C. & Aoun, M. (2012).
M-ficolin levels are associated with the occurrence of severe infections in patients with haematological cancer undergoing chemotherapy.
Clinical and Experimental Immunology. Supplement,
167(2), 303-8.
https://doi.org/10.1111/j.1365-2249.2011.04512.x
Ammitzbøll, C. G., Kjær, T. R., Steffensen, R.
, Stengaard-Pedersen, K., Nielsen, H. J.
, Thiel, S., Bøgsted, M. & Jensenius, J. C. (2012).
Non-Synonymous Polymorphisms in the FCN1 Gene Determine Ligand-Binding Ability and Serum Levels of M-Ficolin.
P L o S One,
7(11), e50585.
https://doi.org/10.1371/journal.pone.0050585
Kidmose, R. T., Laursen, N. S., Dobó, J.
, Kjaer, T. R., Sirotkina, S., Yatime, L., Sottrup-Jensen, L.
, Thiel, S., Gál, P.
& Andersen, G. R. (2012).
Structural basis for activation of the complement system by component C4 cleavage.
Proceedings of the National Academy of Sciences,
109(38), 15425-15430.
https://doi.org/10.1073/pnas.1208031109
Høyem, P. H., Bruun, J. M.
, Pedersen, S. B., Thiel, S., Richelsen, B., Christiansen, J. S.
& Hansen, T. K. (2012).
The effect of weight loss on serum mannose-binding lectin levels.
Clinical & Developmental Immunology,
2012, 354894.
https://doi.org/10.1155/2012/354894
Gjelstrup, L. C., Kaspersen, J. D., Behrens, M. A.
, Pedersen, J. S., Thiel, S., Kingshott, P., Oliveira, C. L. P., Thielens, N. M.
& Vorup-Jensen, T. (2012).
The role of nanometer-scaled ligand patterns in polyvalent binding by large mannan-binding lectin oligomers.
Journal of Immunology,
188(3), 1292-306.
https://doi.org/10.4049/jimmunol.1103012
Reichhardt, M. P., Loimaranta, V.
, Thiel, S., Finne, J., Meri, S. & Jarva, H. (2012).
The salivary scavenger and agglutinin binds MBL and regulates the lectin pathway of complement in solution and on surfaces.
Frontiers in Immunology,
3, 205.
https://doi.org/10.3389/fimmu.2012.00205
Degn, S. E., Andersen, S. H., Jensen, L., Thiel, S. & Jensenius, J. C. (2011).
Assay interference caused by antibodies reacting with rat kappa light-chain in human sera.
Journal of Immunological Methods,
372(1-2), 204-8.
https://doi.org/10.1016/j.jim.2011.06.030
Østergaard, J., Thiel, S., Hansen, T. K., Rasch, R. & Flyvbjerg, A. (2011).
Comment on: Lin et al. (2010) Immune Cell-Derived C3 Is Required for Autoimmune Diabetes Induced by Multiple Low Doses of Streptozotocin. Diabetes;59: 2247-2252.
Diabetes,
60(1), e7-8.
https://doi.org/10.2337/db10-1298