Research

There are three main focus areas of The Scientist's group:

a) The understanding of how small non-coding RNA and circular RNA contribute to cell maintenance and disease development with a primary aim of defining new targets for disease intervention.

b) The creation of novel bioimaging and delivery systems for gene medicine including siRNA, miRNA mimics, antimiRs (antisense targeting microRNA) with a specific focus on inflammation, cancer, influenza, and regeneration of damaged tissue (tissue engineering).

c) Design and construction of functionalized self assembled DNA and RNA nanostructures capable of complex biosensing, coupled with controlled action e.g. drug release, enzyme activation, and receptor signaling.

Recent publications

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Li, Z., Hu, Y., Miao, Z., Xu, H., Li, C., Zhao, Y., Li, Z., Chang, M., Ma, Z., Sun, Y., Besenbacher, F., Huang, P. & Yu, M. (2018). Dual-Stimuli Responsive Bismuth Nanoraspberries for Multimodal Imaging and Combined Cancer Therapy. Nano Letters, 18(11), 6778-6788. https://doi.org/10.1021/acs.nanolett.8b02639

Dai, Y., Li, C., Shen, Y., Zhu, S., Hvid, M. S., Wu, L. C., Skibsted, J., Li, Y., Niemantsverdriet, J. W. H., Besenbacher, F., Lock, N. & Su, R. (2018). Efficient Solar-Driven Hydrogen Transfer by Bismuth-Based Photocatalyst with Engineered Basic Sites. Journal of the American Chemical Society, 140(48), 16711-16719. https://doi.org/10.1021/jacs.8b09796

Chen, C., Ding, P., Mura, M., Chen, Y., Sun, Y., Kantorovich, L. N., Gersen, H., Besenbacher, F. & Yu, M. (2018). Formation of Hypoxanthine Tetrad by Reaction with Sodium Chloride: From Planar to Stereo. Angewandte Chemie International Edition, 57(49), 16015-16019. https://doi.org/10.1002/anie.201808613

Jiang, Z., Zhang, S., Klausen, L. H., Song, J., Li, Q., Wang, Z., Stokke, B. T., Huang, Y., Besenbacher, F., Nielsen, L. P. & Dong, M. (2018). In vitro single-cell dissection revealing the interior structure of cable bacteria. Proceedings of the National Academy of Sciences (PNAS), 115(34), 8517-8522. https://doi.org/10.1073/pnas.1807562115

Korablov, D., Besenbacher, F. & Jensen, T. R. (2018). Kinetics and thermodynamics of hydrogenation-dehydrogenation for Mg-25%TM (TM = Ti, Nb or V) composites synthesized by reactive ball milling in hydrogen. International Journal of Hydrogen Energy, 43(34), 16804-16814. https://doi.org/10.1016/j.ijhydene.2018.05.091

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Group leader

Group members

Full list of publications

Revised 08.12.2025

Lise Refstrup Linnebjerg Pedersen