Research

There are three main focus areas of The Scientist's group:

a) The understanding of how small non-coding RNA and circular RNA contribute to cell maintenance and disease development with a primary aim of defining new targets for disease intervention.

b) The creation of novel bioimaging and delivery systems for gene medicine including siRNA, miRNA mimics, antimiRs (antisense targeting microRNA) with a specific focus on inflammation, cancer, influenza, and regeneration of damaged tissue (tissue engineering).

c) Design and construction of functionalized self assembled DNA and RNA nanostructures capable of complex biosensing, coupled with controlled action e.g. drug release, enzyme activation, and receptor signaling.

Recent publications

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Thostrup, P., Christoffersen, E., Lorensen, H. T., Jacobsen, K. W., Besenbacher, F. & Nørskov, J. K. (2001). Adsorption-induced step formation. Physical Review Letters, 87, 126102.

Petersen, L., Schunack, M., Schaefer, B., Linderoth, T. R., Rasmussen, P. B., Sprunger, P. T., Lægsgaard, E., Stensgaard, I. & Besenbacher, F. (2001). A fast-scanning, low and variable-temperature Scanning Tunneling Microscope. Review of Sci. Instruments, 72, 1438.

Lægsgaard, E., Österlund, L., Thostrup, P., Rasmussen, P. B., Stensgaard, I. & Besenbacher, F. (2001). A high-pressure scanning tunnelling microscope. Rev. Sci. Instr., 72, 3537.

Schunack, M., Petersen, L., Kühnle, A., Lægsgaard, E., Stensgaard, I., Johannsen, I. & Besenbacher, F. (2001). Anchoring of organic molecules to a metal surface: HtBDC on Cu(110). Physical Review Letters, 86, 456.

Højrup Hansen, K., Sljivancanin, Z., Hammer, B., Lægsgaard, E., Besenbacher, F. & Stensgaard, I. (2001). An STM and DFT study of the ordered structures of NO on Pd(111). Surf. Science, 496.

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