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Maria Andreasen

Title

Associate Professor

Primary affiliation

Maria Andreasen

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Profile

Associate Professor at Department of Biomedicine, Aarhus University. I have an international group of postdocs and PhD students who focuses on protein self-assembly in bacterial biofilms related to chronic infections and antibiotic resistance. I have a master’s degree in Medical Biotechnology and a PhD degree in Nanotechnology and Protein Biophysics. I have experience with biophysical protein characterization, protein aggregation and functional amyloids from bacteria.

Research

Biofilm-producing bacteria constitute a significant health concern since 80% of all chronic infections are either related to or caused by both biofilm formation and biofilm-mediated resistance to antimicrobial and antibiotic therapies. The structural components of bacterial biofilms are aggregated proteins known as functional bacterial amyloids (FuBA). Occurrence of FuBA in the biofilm renders the biofilm impossible to disassemble. Our research activities are focused on understanding the molecular mechanisms involved in the formation FuBA, the structure of the FuBA and how the structure is related to the function of the FuBA.
We use biophysical techniques to investigate the kinetics of functional amyloid formation, the structure of the formed amyloids and how the process is adapting to changes in the environment. 

Teaching activities

I am part of the team that teaches Functional Anatomy and Histology to 2nd semester medical students. I also have experience teaching Cell Biology to 1st semester medical students. I also supervise bachelor’s students in both theoretical and experimental bachelor’s projects, master’s students and Ph.D. students. 

Job responsibilities

My primary area of responsibility is leadership of my research group investigating functional amyloid formation from bacterial biofilm aiming to develop new treatment strategies to combat biofilm associated infections and antibiotic resistance. I also contribute to teaching medical students and student supervision. Additionally, I am also an AIAS Associate Fellow and a certified radiation protection coordinator.

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