Professor Jørgen Kjems

Recent publications

Scoyni, F., Sitnikova, V., Giudice, L., Korhonen, P., Trevisan, D. M., Hernandez de Sande, A., Gomez-Budia, M., Giniatullina, R., Ugidos, I. F., Dhungana, H., Pistono, C., Korvenlaita, N., Välimäki, N. N., Kangas, S. M., Hiltunen, A. E., Gribchenko, E., Kaikkonen-Määttä, M. U., Koistinaho, J., Ylä-Herttuala, S. ... Malm, T. (2024). ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling. Cell Reports, 43(3), Article 113862. https://doi.org/10.1016/j.celrep.2024.113862

Vangoor, V. R., Giuliani, G., de Wit, M., Rangel, C. K., Venø, M. T., Schulte, J. T., Gomes-Duarte, A., Senthilkumar, K., Puhakka, N., Kjems, J., de Graan, P. N. E. & Pasterkamp, R. J. (2024). Compartment-specific small non-coding RNA changes and nucleolar defects in human mesial temporal lobe epilepsy. Acta Neuropathologica, 148(1), Article 61. https://doi.org/10.1007/s00401-024-02817-8

Zhang, X., Malle, M. G., Thomsen, R. P., Sørensen, R. S., Sørensen, E. W., Hatzakis, N. S. & Kjems, J. (2024). Deconvoluting the Effect of Cell-Penetrating Peptides for Enhanced and Controlled Insertion of Large-Scale DNA Nanopores. A C S Applied Materials and Interfaces, 16(15), 18422-18433. https://doi.org/10.1021/acsami.3c18636

Baindoor, S., Gibriel, H. A. Y., Venø, M. T., Su, J., Morrissey, E. P., Jirström, E., Woods, I., Kenny, A., Alves, M., Halang, L., Fabbrizio, P., Bilen, M., Engel, T., Hogg, M. C., Bendotti, C., Nardo, G., Slack, R. S., Kjems, J. & Prehn, J. H. M. (2024). Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration. Disease Models & Mechanisms, 17(11), Article dmm050870. https://doi.org/10.1242/dmm.050870

Smidt, J. M., Märcher, A., Skaanning, M. K., El-Chami, K., Teodori, L., Omer, M., Kjems, J. & Gothelf, K. V. (2024). Dual-Targeting of the HER2 Cancer Receptor with an Antibody-Directed Enzyme and a Nanobody-Guided MMAE Prodrug Scaffold. ChemBioChem, 25(18), Article e202400437. https://doi.org/10.1002/cbic.202400437

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Shakeran, Z., Keyhanfar, M., Varshosaz, J. & Sutherland, D. S. (2021). Biodegradable nanocarriers based on chitosan-modified mesoporous silica nanoparticles for delivery of methotrexate for application in breast cancer treatment. Materials Science and Engineering C, 118, Article 111526. https://doi.org/10.1016/j.msec.2020.111526

Juul-Madsen, K., Troldborg, A., Wittenborn, T. R., Axelsen, M. G., Zhao, H., Klausen, L. H., Luecke, S., Paludan, S. R., Stengaard-Pedersen, K., Dong, M., Møller, H. J., Thiel, S., Jensen, H., Schuck, P., Sutherland, D. S., Degn, S. E. & Vorup-Jensen, T. (2021). Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus. Proceedings of the National Academy of Sciences (PNAS), 118(30), Article e2106647118. https://doi.org/10.1073/pnas.2106647118

Ma, R., Sutherland, D. S. & Shi, Y. (2021). Harmonic generation in transition metal dichalcogenides and their heterostructures. Materials Today, 50, 570-586. https://doi.org/10.1016/j.mattod.2021.07.023

Cao, M., Li, B., Guo, M., Liu, Y., Zhang, L., Wang, Y., Hu, B., Li, J., Sutherland, D. S., Wang, L. & Chen, C. (2021). In vivo percutaneous permeation of gold nanomaterials in consumer cosmetics: implication in dermal safety assessment of consumer nanoproducts. Nanotoxicology, 15(1), 131-144. https://doi.org/10.1080/17435390.2020.1860264

Aliakbari, F., Mohammad-Beigi, H., Abbasi, S., Rezaei-Ghaleh, N., Lermyte, F., Parsafar, S., Becker, S., Tafreshi, A. P., O'Connor, P. B., Collingwood, J. F., Christiansen, G., Sutherland, D. S., Jensen, P. H., Morshedi, D. & Otzen, D. E. (2021). Multiple Protective Roles of Nanoliposome-Incorporated Baicalein against Alpha-Synuclein Aggregates. Advanced Functional Materials, 31(7), Article 2007765. https://doi.org/10.1002/adfm.202007765

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Professor Steffen Thiel

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Vils, S. R., Troldborg, A., Hvas, A.-M. & Thiel, S. (2023). Platelets and the Lectin Pathway of Complement Activation in Patients with Systemic Lupus Erythematosus or Antiphospholipid Syndrome. TH Open, 7(2), e155-e167. https://doi.org/10.1055/a-2087-0314

Ryo, L. B., Haslund, D., Rovsing, A. B., Pihl, R., Sanrattana, W., de Maat, S., Palarasah, Y., Maas, C., Thiel, S. & Mikkelsen, J. G. (2023). Restriction of C1-inhibitor activity in hereditary angioedema by dominant-negative effects of disease-associated SERPING1 gene variants. Journal of Allergy and Clinical Immunology, 152(5), 1218-1236.e9. https://doi.org/10.1016/j.jaci.2023.04.023

Lorentzen, J., Olesen, H. G., Hansen, A. G., Thiel, S., Birkelund, S., Andersen, C. B. F. & Andersen, G. R. (2023). Trypanosoma brucei Invariant Surface gp65 Inhibits the Alternative Pathway of Complement by Accelerating C3b Degradation. Journal of Immunology, 211(5), 862-873. https://doi.org/10.4049/jimmunol.2300128

Bernth Jensen, J. M., Hansen, A. T., Söderström, A., Jørgensen, C. S., Larsen, C. S., Skov Sørensen, U. B., Thiel, S. & Petersen, M. S. (2022). A low level of naturally occurring antibodies associates with functional antibody deficiency. Clinical Immunology, 241, Article 109070. https://doi.org/10.1016/j.clim.2022.109070

Elbæk Mistegård, C., Troldborg, A., Hansen, A., Thiel, S., Jurik, A. G., Kiil, R. M. Ø., Christiansen, A. A., Hendricks, O. & Loft, A. G. R. (2022). Complement proteins are elevated in patients with axSpA compared with relevant controls with low back pain and axSpA-features without axSpA.. Poster session presented at EULAR 2022, Copenhagen, Denmark.

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Firl, D. J., Degn, S. E., Padera, T. & Carroll, M. C. (2018). Capturing change in clonal composition amongst single mouse germinal centers. eLife, 7, Article e33051. https://doi.org/10.7554/eLife.33051

Psianou, K., Panagoulias, I., Papanastasiou, A. D., de Lastic, A.-L., Rodi, M., Spantidea, P. I., Degn, S. E., Georgiou, P. & Mouzaki, A. (2018). Clinical and immunological parameters of Sjögren's syndrome. Autoimmunity Reviews, 17(10), 1053-1064. https://doi.org/10.1016/j.autrev.2018.05.005

Degn, S. E., van der Poel, C. E., Firl, D. J., Ayoglu, B., Al Qureshah, F. A., Bajic, G., Mesin, L., Reynaud, C.-A., Weill, J.-C., Utz, P. J., Victora, G. D. & Carroll, M. C. (2017). Clonal Evolution of Autoreactive Germinal Centers. Cell, 170(5), 913-926.e19. https://doi.org/10.1016/j.cell.2017.07.026