Professor Jørgen Kjems

Recent publications

Zhang, X., Hitt, P., Wanunu, M. & Kjems, J. (2026). Scalable Production of DNA-Probe-Functionalized Heteromeric MspA Nanopores for Biosensing. ACS Applied Materials and Interfaces, 18(10), 14531-14539. https://doi.org/10.1021/acsami.5c21011

Baindoor, S., Gibriel, H. A. Y., Kool, L., Su, J., Demaegd, K. C., Venø, M. T., Van Den Berg, L. H., Kjems, J., Van Es, M. A. & Prehn, J. H. M. (2026). Serum small non-coding RNA define molecular subtypes in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 27(3-4), 383-392. https://doi.org/10.1080/21678421.2025.2574690

Demaegd, K. C., Kool, L., Baindoor, S., Donovan, P. D., Su, J., Westeneng, H. J., van Eijk, R. P. A., Geoghegan, G., Perez Morrissey, E., Halang, L., Poesen, K., Masrori, P., Gibriel, H. A. Y., Jirström, E., Venø, M. T., Kjems, J., Hardiman, O., Veldink, J. H., Kenna, K. ... van Es, M. A. (2026). Small RNA sequencing identifies serum tDR-1:34-Gly-GCC tiRNA levels as a biomarker for survival in amyotrophic lateral sclerosis. iScience, 29(5), Article 115636. https://doi.org/10.1016/j.isci.2026.115636

Vinther, S. C., Resag, A., Le, K. T. T., Zelle-Rieser, C. C., Strandt, H., Malle, M. G., Christiansen, S. H., Del Frari, B., Stigger, T., Schilling, B., Wohlfarth, J., Thiel, S., Valero, J., Stoitzner, P. & Kjems, J. (2026). Targeting Langerhans cells using a modular mannosylated nucleic acid-based vaccine platform. Journal of Controlled Release, 392, 114741. Article 114741. https://doi.org/10.1016/j.jconrel.2026.114741

Cerda-Jara, C. A., Scoyni, F., Zolotarov, G., Bhaskar, P., León-Periñán, D., Kjems, J. & Rajewsky, N. (2026). The history and function of a circular RNA. Nature Communications, 17(1), Article 3862. https://doi.org/10.1038/s41467-026-71822-0

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Juul-Madsen, K., Rudolph, I. M., Gomes, J. P., Meyer, K., Ovesen, P. L., Gorniak-Walas, M., Kokoli, M., Telugu, N. S., von Tangen Sivertsen, M., Febbraro, F., Sutherland, D. S., Palmfeldt, J., Diecke, S., Andersen, O. M., Selbach, M. & Willnow, T. E. (2025). Familial Alzheimer's disease mutation identifies novel role of SORLA in release of neurotrophic exosomes. Alzheimer's and Dementia, 21(9), Article e70591. https://doi.org/10.1002/alz.70591

Gothelf, K. V., Kjems, J., Otzen, D. E., Nielsen, N. C., Hornekær, L., Zelikin, A., Pedersen, J. S., Vorup-Jensen, T. & Sutherland, D. S. (2025). Ingen reel mulighed for medarbejdere for at gøre indsigelse mod ledelsens beslutning om at afvikle iNANO. Omnibus, 2025(Juni). https://omnibus.au.dk/arkiv/vis/artikel/aabent-brev-medarbejdere-er-sat-uden-for-indflydelse-i-ledelsens-beslutning-om-at-afvikle-inano

Okholm, K. R., Nooteboom, S. W., Zijlstra, P. & Sutherland, D. S. (2025). Multivalency Studied at the Single Molecule Level via Plasmon Enhanced Fluorescence. International Conference on Metamaterials, Photonic Crystals and Plasmonics, 1303-1304.

Shahrokhtash, A., Sivertsen, M. V. T., Laursen, S. H. & Sutherland, D. S. (2025). Nanoscale Cellular Traction Force Quantification: CRISPR-Cas12a Supercharged DNA Tension Sensors in Nanoclustered Ligand Patterns. ACS applied materials & interfaces, 17(5), 7339-7352. https://doi.org/10.1021/acsami.4c18358

Teodori, L., Shahrokhtash, A., Sørensen, E. A., Zhang, X., Malle, M. G., Sutherland, D. S. & Kjems, J. (2025). Nanoscale Precise Stamping of Biomolecule Patterns Using DNA Origami. ACS Nano, 19(42), 36931-36942. https://doi.org/10.1021/acsnano.5c07651

Displaying results 6 to 10 out of 187

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Nielsen, J., Pedersen, J. N., Kleijwegt, G., Nowak, J. S., Nami, F., Johansen, C., Sassetti, E., Berg, B. B., Lyngsø, N. M., Brøchner, B. H., Holm Carlson, J., Simonsen, A. J., Pallisgaard Olsen, W., Simonsen, B. W., Mikkelsen, J. H., Sereika-Bejder, V., Lauritsen, J. A., Merrild, K. F., Malle, M. G. ... Otzen, D. E. (2025). Nanobodies raised against the cytotoxic α-synuclein oligomer are oligomer-specific and promote its cellular uptake. npj biosensing, 2, Article 23. https://doi.org/10.1038/s44328-025-00042-1

Mohora, I., Patiño Guillén, G., Neis, K., Valero, J., Keyser, U. F. & Bošković, F. (2025). Programmable RNA Nanostructures Enable Nanopore Detection of Cotranscriptionally Introduced RNA Modifications. Nano Letters, 25(32), 12184-12192. https://doi.org/10.1021/acs.nanolett.5c02391

Civit, L., Moradzadeh, N., Jonczyk, A., Neckermann, P., Asbach, B., Peterhoff, D., Wagner, R., Famulok, M., Mayer, G., Kjems, J. & Valero, J. (2024). A Multi-Faceted Binding Assessment of Aptamers Targeting the SARS-CoV-2 Spike Protein. International Journal of Molecular Sciences , 25(9), Article 4642. https://doi.org/10.3390/ijms25094642

Nielsen, J., Lauritsen, J., Pedersen, J. N., Nowak, J. S., Bendtsen, M. K., Kleijwegt, G., Lusser, K., Pitarch, L. C., Moreno, J. V., Schneider, M. M., Krainer, G., Goksøyr, L., Khalifé, P., Kaalund, S. S., Aznar, S., Kjærgaard, M., Sereikaité, V., Strømgaard, K., Knowles, T. P. J. ... Otzen, D. E. (2024). Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers. npj Parkinson's Disease , 10(1), Article 139. https://doi.org/10.1038/s41531-024-00747-6

Malle, M. G., Song, P., Löffler, P. M. G., Kalisi, N., Yan, Y., Valero, J., Vogel, S. & Kjems, J. (2024). Programmable RNA Loading of Extracellular Vesicles with Toehold-Release Purification. Journal of the American Chemical Society, 146(18), 12410-12422. https://doi.org/10.1021/JACS.3C13123

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Mistegaard, C., Troldborg, A., Torgutalp, M., Loft, A. G., Thiel, S., Muche, B., Rios Rodriguez, V., Protopopov, M., Listing, J., Sieper, J., Poddubnyy, D. & Proft, F. (2025). Complement proteins in axial spondyloarthritis: associations with disease activity and TNFi treatment response in a multicentre RCT. Rheumatology Advances in Practice, 9(1), Article rkaf007. https://doi.org/10.1093/rap/rkaf007

Mistegaard, C., Troldborg, A., Torgutalp, M., Loft, A. G., Thiel, S., Muche, B., Rios Rodriguez, V., Protopopov, M., Listing, J., Sieper, J., Poddubnyy, D. & Proft, F. (2025). Complement system activation is associated with spinal radiographic progression in axial spondyloarthritis after 2 years of follow-up: findings from the CONSUL RCT. RMD Open, 11(4), Article e006087. https://doi.org/10.1136/rmdopen-2025-006087

Hymøller, K. M., Crone, L., Thiel, S. & Hennet, T. (2025). Differential Recognition of Lipopolysaccharide O-Antigens by the Pattern Recognition Molecules Mannan-Binding Lectin and Ficolins of the Complement System. Journal of Innate Immunity, 17(1), 397–413. https://doi.org/10.1159/000547441

Bernth Jensen, J. M., Dinh, K. M., Hindhede, L., Erikstrup, L. T., Hansen, A. G., Hymøller, K. M., Ostrowski, S. R., Pedersen, O. B. V., Christiansen, S. H., Sørensen, U. B. S., Thiel, S. & Erikstrup, C. (2025). Impact of Staphylococcus aureus colonization and skin abscesses on formation of human anti-αGal antibodies. Medical Microbiology and Immunology, 214(1), Article 23. https://doi.org/10.1007/s00430-025-00833-3

Sagedal, S., Hovd, M., Åsberg, A., Mollnes, T. E., Klingenberg, O., Heldal, T. F., Witczak, B. J., Hejlesen, T. K., Troldborg, A. & Thiel, S. (2025). Increased levels of ficolin-1 and of C3dg are independently associated with high risk of infection in patients with chronic kidney disease: a prospective cohort study. Frontiers in Immunology, 16, Article 1645347. https://doi.org/10.3389/fimmu.2025.1645347

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Pilati, D., Agyei, E. K., Elkhashab, M., Fuchs, E., Nielsen, I. H., Bjerg, T. W., Anthi, A. K., Jiménez-Reinoso, A., Iversen, M. B., Pohl, L., Narita, R., Frago, S., Jakobsen, M. R., Andersen, J. T., Degn, S. E., Paludan, S. R., Alvarez-Vallina, L. & Howard, K. A. (2025). Exploiting FcRn engagement of an albumin-CpG oligonucleotide covalent conjugate for potent TLR9 immune induction. Journal of Biological Chemistry, 301(6), Article 108508. https://doi.org/10.1016/j.jbc.2025.108508

Rasmussen, M. Q., Bønnelykke-Behrndtz, M. L., Merrild, C., Tvilling, I. K. S., Christensen, J. N., Nielsen, M. M., Georgsen, J. B., Naumann, N., Gudbergsson, J. M., Etzerodt, A., Pedersen, J. S., Jenkins, R. W., Degn, S. E., Moestrup, S. K., Schmidt, H., Steiniche, T. & Madsen, M. (2025). LRP2 Expression in Melanoma Is Associated With a Transitory Cell State, Increased T Cell Infiltration, and Is Upregulated by IFNy Signaling. Pigment Cell & Melanoma Research, 38(5), Article e70053. https://doi.org/10.1111/pcmr.70053

Fonager, S. V., Winther, G., Weber, Y. C. L., Wittenborn, T. R., Kastberg, K. S., Terczyńska-Dyla, E., Jensen, L., Hansen, L. A., Carroll, M. C., Luo, Y., Lin, L. & Degn, S. E. (2025). Maternal imprinting of autoreactivity in a murine model of systemic lupus erythematosus. Brain, Behavior, and Immunity, 129, 921-934. https://doi.org/10.1016/j.bbi.2025.07.025

Rovsing, A. B., Green, K., Jensen, L., Nielsen, I. H., Mikkelsen, J. G. & Degn, S. E. (2025). Multiparametric Optimization of Human Primary B-Cell Cultures Using Design of Experiments. Scandinavian Journal of Immunology, 102(2), Article e70043. https://doi.org/10.1111/sji.70043

Degn, S. E. & Tolar, P. (2025). Towards a unifying model for B-cell receptor triggering. Nature Reviews Immunology, 25(2), 77-91. Article 976. https://doi.org/10.1038/s41577-024-01073-x

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Professor Dr. Ralf Jungmann

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Interdisciplinary Nanoscience Center

CellPAT

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Professor Jørgen Kjems

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Professor Duncan Sutherland

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Tenure-track assistant professor Julián Valero

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Professor Steffen Thiel

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Professor Søren Degn

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Professor Fiona Watt

Professor Dr. Ralf Jungmann