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Professor Jørgen Kjems

Jørgen Kjems

Professor Department of Molecular Biology and Genetics - RNA Biology and Innovation

M jk@mbg.au.dk

P +4587155494
P +4528992086

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Recent publications

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Dinesen, A., Andersen, V. L., Elkhashab, M., Pilati, D., Bech, P., Fuchs, E., Samuelsen, T. R., Winther, A., Cai, Y., Märcher, A., Wall, A., Omer, M., Nielsen, J. S., Chudasama, V., Baker, J. R., Gothelf, K. V., Wengel, J., Kjems, J. & Howard, K. A. (2024). An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjugate Chemistry, 35(2), 214-222. https://doi.org/10.1021/acs.bioconjchem.3c00491

Vieira de Sá, R., Sudria-Lopez, E., Cañizares Luna, M., Harschnitz, O., van den Heuvel, D. M. A., Kling, S., Vonk, D., Westeneng, H. J., Karst, H., Bloemenkamp, L., Varderidou-Minasian, S., Schlegel, D. K., Mars, M., Broekhoven, M. H., van Kronenburg, N. C. H., Adolfs, Y., Vangoor, V. R., de Jongh, R., Ljubikj, T. ... Pasterkamp, R. J. (2024). ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes. Nature Communications, 15(1), Article 7484. https://doi.org/10.1038/s41467-024-51676-0

Okholm, T. L. H., Kamstrup, A. B., Nielsen, M. M., Hollensen, A. K., Graversgaard, M. L., Sørensen, M. H., Kristensen, L. S., Vang, S., Park, S. S., Yeo, E., Dyrskjøt, L., Kjems, J., Pedersen, J. S. & Damgaard, C. K. (2024). circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA. eLife, 13, Article RP91783. https://doi.org/10.7554/eLife.91783

Rybiczka-Tešulov, M., Garritsen, O., Venø, M. T., Wieg, L., Dijk, R. V., Rahimi, K., Gomes-Duarte, A., Wit, M. D., van de Haar, L. L., Michels, L., van Kronenburg, N. C. H., van der Meer, C., Kjems, J., Vangoor, V. R. & Pasterkamp, R. J. (2024). Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development. Nature Communications, 15(1), Article 6773. https://doi.org/10.1038/s41467-024-51041-1

Scoyni, F., Sitnikova, V., Giudice, L., Korhonen, P., Trevisan, D. M., Hernandez de Sande, A., Gomez-Budia, M., Giniatullina, R., Ugidos, I. F., Dhungana, H., Pistono, C., Korvenlaita, N., Välimäki, N. N., Kangas, S. M., Hiltunen, A. E., Gribchenko, E., Kaikkonen-Määttä, M. U., Koistinaho, J., Ylä-Herttuala, S. ... Malm, T. (2024). ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling. Cell Reports, 43(3), Article 113862. https://doi.org/10.1016/j.celrep.2024.113862

Displaying results 6 to 10 out of 420

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Professor Duncan Sutherland

Duncan Sutherland

Professor Interdisciplinary Nanoscience Center - INANO-Fysik, iNANO-huset

M duncan@inano.au.dk
H 1592, 120
P +4587156714
P +4523385789

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Nooteboom, S. W., Okholm, K. R., Lamberti, V., Oomen, B., Sutherland, D. S. & Zijlstra, P. (2024). Rate-Engineered Plasmon-Enhanced Fluorescence for Real-Time Microsecond Dynamics of Single Biomolecules. Nano Letters, 24(37), 11641-11647. https://doi.org/10.1021/acs.nanolett.4c03220

Heidarizadeh, M., Noorbakhsh, A., Razmjou, A. & Sutherland, D. S. (2024). Silk Fibroin Fibers with In Situ Growth of ZIF-67 Nanoparticles for Membranes with Highly Efficient Nanofluidic Ion Transport. ACS Applied Nano Materials, 7(16), 19481-19492. https://doi.org/10.1021/acsanm.4c03394

Okholm, K. R., Nooteboom, S. W., Vinther, J. N., Lamberti, V., Dey, S., Andersen, E. S., Zijlstra, P. & Sutherland, D. S. (2024). Single-Molecule Multivalent Interactions Revealed by Plasmon-Enhanced Fluorescence. ACS Nano, 18(52), 35429-35442. https://doi.org/10.1021/acsnano.4c12600

Shahrokhtash, A. & Sutherland, D. S. (2024). Smart Biointerfaces via Click Chemistry-Enabled Nanopatterning of Multiple Bioligands and DNA Force Sensors. ACS applied materials & interfaces, 16(17), 21534-21545. https://doi.org/10.1021/acsami.4c00831

Tariq, M., Saqib, M., Rahim, A. & Sutherland, D. S. (2024). The substantial role of TiO₂ in bimetallic alloy nanoparticle arrangement: electrocatalytic determination of glucose at Ni-Co@TiO₂@GCE. Journal of Materials Science: Materials in Electronics, 35(22), Article 1525. https://doi.org/10.1007/s10854-024-13272-2

Displaying results 6 to 10 out of 175

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Tenure-track assistant professor Julián Valero

Julián Valero Moreno

Tenure Track Assistant Professor Department of Molecular Biology and Genetics - RNA Biology and Innovation

M jvalero@mbg.au.dk
H 1590, 238
P +4587150705

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Yu, Z., Centola, M., Valero, J., Matthies, M., Šulc, P. & Famulok, M. (2021). A Self-Regulating DNA Rotaxane Linear Actuator Driven by Chemical Energy. Journal of the American Chemical Society, 143(33), 13292-13298. https://doi.org/10.1021/jacs.1c06226

Valero, J., Civit, L., Dupont, D. M., Selnihhin, D., Reinert, L. S., Idorn, M., Israels, B. A., Bednarz, A. M., Bus, C., Asbach, B., Peterhoff, D., Pedersen, F. S., Birkedal, V., Wagner, R., Paludan, S. R. & Kjems, J. (2021). A serum-stable RNA aptamer specific for SARS-CoV-2 neutralizes viral entry. Proceedings of the National Academy of Sciences (PNAS), 118(50), Article e2112942118. https://doi.org/10.1073/pnas.2112942118

Valero, J. & Skugor, M. (2020). Mechanisms, Methods of Tracking and Applications of DNA Walkers: A Review. ChemPhysChem, 21(17), 1971-1988. https://doi.org/10.1002/cphc.202000235

Valero, J. & Famulok, M. (2020). Regeneration of Burnt Bridges on a DNA Catenane Walker. Angewandte Chemie - International Edition, 59(38), 16366-16370. https://doi.org/10.1002/anie.202004447

Valero Moreno, J., Centola, M., Ma, Y., Škugor, M., Yu, Z., Haydell, M. W., Keppner, D. & Famulok, M. (2019). Design, assembly, characterization, and operation of double-stranded interlocked DNA nanostructures. Nature Protocols, 14(10), 2818-2855. https://doi.org/10.1038/s41596-019-0198-7

Displaying results 6 to 10 out of 14

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Professor Steffen Thiel

Steffen Thiel

Professor with Special Responsibilities Department of Biomedicine - Research and Education, Bartholin Building

M st@biomed.au.dk
H 1242, 129
P +4529270890
P +4529270890

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Pedersen, K., Laursen, N. S., Hansen, A. G., Palarasah, Y. & Thiel, S. (2024). Development of an immunoassay for quantification of soluble human CD40L (CD154) in plasma and serum samples. Journal of Immunological Methods, 531, Article 113710. https://doi.org/10.1016/j.jim.2024.113710

Isayeva, G., Rumora, K., Potlukova, E., Leibfarth, J.-P., Schäfer, I., Bartha, Z., Zellweger, M. J., Trendelenburg, M., Hejlesen, T. K., Hansen, A. G., Thiel, S. & Mueller, C. (2024). Diagnostic and prognostic value of mannan-binding lectin associated protein (MAp19) for functionally relevant coronary artery disease. Clinica Chimica Acta, 558, Article 119668. https://doi.org/10.1016/j.cca.2024.119668

Jensen, M., Eickhoff, M. K., Persson, F., Rossing, P., Thiel, S., Hansen, S. W. K., Palarasah, Y., Svenningsen, P. & Jensen, B. L. (2024). Effect of dapagliflozin on collectins and complement activation in plasma from patients with type 2 diabetes and albuminuria: Data from the DapKid cohort. Immunobiology, 229(3), 152797. Article 152797. https://doi.org/10.1016/j.imbio.2024.152797

Mistegård, C. E., Troldborg, A., Loft, A. G., Thiel, S., Spiller, L., Protopopov, M., Rios Rodriguez, V., Muche, B., Rademacher, J., Weber, A. K., Lüders, S., Sieper, J., Poddubnyy, D. & Proft, F. (2024). Exploring complement biomarkers in suspected axial spondyloarthritis. RMD Open, 10(2), Article e004127. https://doi.org/10.1136/rmdopen-2024-004127

Troldborg, A., Godnic-Polai, Z., Cervenak, L., Hansen, A. G., Farkas, H. & Thiel, S. (2024). Inter-α-trypsin inhibitor heavy chain 4 (ITIH4) as a compensatory protease inhibitor in hereditary angioedema. The Journal of allergy and clinical immunology, 154(2), 468-479.e6. https://doi.org/10.1016/j.jaci.2024.03.028

Displaying results 6 to 10 out of 500

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Professor Søren Degn

Søren Egedal Degn

Associate Professor Department of Biomedicine - Forskning og uddannelse, Skou-bygningen

M sdegn@biomed.au.dk
H 1116, 356
P +4522141703
P +4522141703

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Krimpenfort, L. T., Degn, S. E. & Heesters, B. A. (2024). The follicular dendritic cell: At the germinal center of autoimmunity? Cell Reports, 43(3), Article 113869. https://doi.org/10.1016/j.celrep.2024.113869

Ferapontov, A., Omer, M., Baudrexel, I., Nielsen, J. S., Dupont, D. M., Juul-Madsen, K., Steen, P., Eklund, A. S., Thiel, S., Vorup-Jensen, T., Jungmann, R., Kjems, J. & Degn, S. E. (2023). Antigen footprint governs activation of the B cell receptor. Nature Communications, 14(1), Article 976. https://doi.org/10.1038/s41467-023-36672-0

Fahlquist-Hagert, C., Wittenborn, T. R., Terczyńska-Dyla, E., Kastberg, K. S., Yang, E., Rallistan, A. N., Markett, Q. R., Winther, G., Fonager, S., Voss, L. F., Pedersen, M. K., van Campen, N., Ferapontov, A., Jensen, L., Huang, J., Nieland, J. D., van der Poel, C. E., Palmfeldt, J., Carroll, M. C. ... Degn, S. E. (2023). Antigen presentation by B cells enables epitope spreading across an MHC barrier. Nature Communications, 14(1), Article 6941. https://doi.org/10.1038/s41467-023-42541-7

Wibrand, C., Wittenborn, T. R., Voss, L. F., Winther, G., Jensen, L., Ferapontov, A., Fonager, S. V., Fahlquist-Hagert, C. & Degn, S. E. (2023). B cell MHC haplotype affects follicular inclusion, germinal center participation and plasma cell differentiation in a mouse model of lupus. Frontiers in Immunology, 14, Article 1258046. https://doi.org/10.3389/fimmu.2023.1258046

Rasmussen, M. Q., Tindbæk, G., Nielsen, M. M., Merrild, C., Steiniche, T., Pedersen, J. S., Moestrup, S. K., Degn, S. E. & Madsen, M. (2023). Epigenetic Silencing of LRP2 Is Associated with Dedifferentiation and Poor Survival in Multiple Solid Tumor Types. Cancers, 15(6), Article 1830. https://doi.org/10.3390/cancers15061830

Displaying results 6 to 10 out of 52

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Professor Fiona Watt

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Professor Dr. Ralf Jungmann

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Revised 13.07.2023

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Anne Færch Nielsen