Professor Jørgen Kjems

Recent publications

Vangoor, V. R., Giuliani, G., de Wit, M., Rangel, C. K., Venø, M. T., Schulte, J. T., Gomes-Duarte, A., Senthilkumar, K., Puhakka, N., Kjems, J., de Graan, P. N. E. & Pasterkamp, R. J. (2024). Compartment-specific small non-coding RNA changes and nucleolar defects in human mesial temporal lobe epilepsy. Acta Neuropathologica, 148(1), Article 61. https://doi.org/10.1007/s00401-024-02817-8

Zhang, X., Malle, M. G., Thomsen, R. P., Sørensen, R. S., Sørensen, E. W., Hatzakis, N. S. & Kjems, J. (2024). Deconvoluting the Effect of Cell-Penetrating Peptides for Enhanced and Controlled Insertion of Large-Scale DNA Nanopores. A C S Applied Materials and Interfaces, 16(15), 18422-18433. https://doi.org/10.1021/acsami.3c18636

Baindoor, S., Gibriel, H. A. Y., Venø, M. T., Su, J., Morrissey, E. P., Jirström, E., Woods, I., Kenny, A., Alves, M., Halang, L., Fabbrizio, P., Bilen, M., Engel, T., Hogg, M. C., Bendotti, C., Nardo, G., Slack, R. S., Kjems, J. & Prehn, J. H. M. (2024). Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration. Disease Models & Mechanisms, 17(11), Article dmm050870. https://doi.org/10.1242/dmm.050870

Smidt, J. M., Märcher, A., Skaanning, M. K., El-Chami, K., Teodori, L., Omer, M., Kjems, J. & Gothelf, K. V. (2024). Dual-Targeting of the HER2 Cancer Receptor with an Antibody-Directed Enzyme and a Nanobody-Guided MMAE Prodrug Scaffold. ChemBioChem, 25(18), Article e202400437. https://doi.org/10.1002/cbic.202400437

Khemka, N., Morris, G., Kazemzadeh, L., Costard, L. S., Neubert, V., Bauer, S., Rosenow, F., Venø, M. T., Kjems, J., Henshall, D. C., Prehn, J. H. M. & Connolly, N. M. C. (2024). Integrative network analysis of miRNA-mRNA expression profiles during epileptogenesis in rats reveals therapeutic targets after emergence of first spontaneous seizure. Scientific Reports, 14(1), Article 15313. https://doi.org/10.1038/s41598-024-66117-7

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Ghorbani, S., Shahrokhtash, A., Gautrot, J. E. & Sutherland, D. S. (2022). Protein Ligand Nanopattern Size Selects for Cellular Adhesion via Hemidesmosomes over Focal Adhesions. Small Methods, 6(6), e2200152. Article 2200152. https://doi.org/10.1002/smtd.202200152

Khateb, H., Sørensen, R. S., Cramer, K., Eklund, A. S., Kjems, J., Meyer, R. L., Jungmann, R. & Sutherland, D. S. (2022). The Role of Nanoscale Distribution of Fibronectin in the Adhesion of Staphylococcus aureus Studied by Protein Patterning and DNA-PAINT. ACS Nano, 16(7), 10392-10403. https://doi.org/10.1021/acsnano.2c00630

Eyni, H., Ghorbani, S., Nazari, H., Hajialyani, M., Razavi Bazaz, S., Mohaqiq, M., Ebrahimi Warkiani, M. & Sutherland, D. S. (2021). Advanced bioengineering of male germ stem cells to preserve fertility. Journal of Tissue Engineering, 12. https://doi.org/10.1177/20417314211060590

Shakeran, Z., Keyhanfar, M., Varshosaz, J. & Sutherland, D. S. (2021). Biodegradable nanocarriers based on chitosan-modified mesoporous silica nanoparticles for delivery of methotrexate for application in breast cancer treatment. Materials Science and Engineering C, 118, Article 111526. https://doi.org/10.1016/j.msec.2020.111526

Juul-Madsen, K., Troldborg, A., Wittenborn, T. R., Axelsen, M. G., Zhao, H., Klausen, L. H., Luecke, S., Paludan, S. R., Stengaard-Pedersen, K., Dong, M., Møller, H. J., Thiel, S., Jensen, H., Schuck, P., Sutherland, D. S., Degn, S. E. & Vorup-Jensen, T. (2021). Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus. Proceedings of the National Academy of Sciences (PNAS), 118(30), Article e2106647118. https://doi.org/10.1073/pnas.2106647118

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Professor Steffen Thiel

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Jensen, R. K., Pihl, R., Gadeberg, T. A. F., Jensen, J. K., Andersen, K. R., Thiel, S., Laursen, N. S. & Andersen, G. R. (2023). Correction: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement (Journal of Biological Chemistry (2018) 293(17) (6269–6281), (S0021925820397313), (10.1074/jbc.RA117.001179)). The Journal of Biological Chemistry, 299(2), Article 102951. https://doi.org/10.1016/j.jbc.2023.102951

Isayeva, G., Potlukova, E., Rumora, K., Lopez Ayala, P., Kurun, A., Leibfarth, J.-P., Schäfer, I., Michel, E., Pesen, K., Zellweger, M. J., Trendelenburg, M., Korsgaard Hejlesen, T., Gudmann Hansen, A., Thiel, S. & Mueller, C. (2023). Diagnostic and Prognostic Value of H-ficolin for Functionally Relevant Coronary Artery Disease. Clinica Chimica Acta, 551, Article 117582. https://doi.org/10.1016/j.cca.2023.117582

Larsen, M. L., Troldborg, A., Toonen, E. J. M., Hurler, L., Prohaszka, Z., Cervenak, L., Hansen, A. G. & Thiel, S. (2023). Differentiating Between Activation via the Lectin or the Classical Complement Pathway in Patients with Systemic Lupus Erythematosus. Clinical and Experimental Immunology, 214(1), 18-25. https://doi.org/10.1093/cei/uxad070

Larsen, J. B., Pihl, R., Aggerbeck, M. A., Larsen, K. M., Hvas, C. L., Johnsen, N., Christensen, M. G., Praetorius, H., Hvas, A.-M. & Thiel, S. (2023). Inter-α-inhibitor heavy chain H4 and sepsis-related coagulation disturbances: Another link between innate immunity and coagulation. Research and Practice in Thrombosis and Haemostasis, 7(2), Article 100078. https://doi.org/10.1016/j.rpth.2023.100078

Vils, S. R., Troldborg, A., Hvas, A.-M. & Thiel, S. (2023). Platelets and the Lectin Pathway of Complement Activation in Patients with Systemic Lupus Erythematosus or Antiphospholipid Syndrome. TH open, 7(2), e155-e167. https://doi.org/10.1055/a-2087-0314

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Psianou, K., Panagoulias, I., Papanastasiou, A. D., de Lastic, A.-L., Rodi, M., Spantidea, P. I., Degn, S. E., Georgiou, P. & Mouzaki, A. (2018). Clinical and immunological parameters of Sjögren's syndrome. Autoimmunity Reviews, 17(10), 1053-1064. https://doi.org/10.1016/j.autrev.2018.05.005

Degn, S. E., van der Poel, C. E., Firl, D. J., Ayoglu, B., Al Qureshah, F. A., Bajic, G., Mesin, L., Reynaud, C.-A., Weill, J.-C., Utz, P. J., Victora, G. D. & Carroll, M. C. (2017). Clonal Evolution of Autoreactive Germinal Centers. Cell, 170(5), 913-926.e19. https://doi.org/10.1016/j.cell.2017.07.026