JØRGEN KJEMS: Nanomedicine

There are three main focus areas in the Kjems lab:

a) The understanding of how small non-coding RNA and circular RNA contribute to cell maintenance and disease development with a primary aim of defining new targets for disease intervention.

b) The creation of novel bioimaging and delivery systems for gene medicine including siRNA, miRNA mimics, antimiRs (antisense targeting microRNA) with a specific focus on inflammation, cancer, influenza, and regeneration of damaged tissue (tissue engineering).

c) Design and construction of functionalized self assembled DNA and RNA nanostructures capable of complex biosensing, coupled with controlled action e.g. drug release, enzyme activation, and receptor signaling.

In CellPAT, Jørgen Kjems contributes with key expertises in applied nanotechnology including biomolecular design, bioconjugation, cell delivery and tissue engineering as well as the more basic molecular biology fields of gene expression and cellular growth and development.

Recent publications

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Kjems, J. & Wengel, J. (2006). Small internally segmented interfering RNA.

Olesen, J. R., Kjems, J. & Besenbacher, F. (2006). Småt blir' godt: Nanomedicin i fremtidens sundhedssektor. Lægen i Midten, (5), 31.

Lützelberger, M. & Kjems, J. (2006). Strategies to identify potential therapeutic target sites in RNA. In V. Erdmann, J. Barciszewski & J. Brosius (Eds.), Handbook of Experimental Pharmacology: RNA Towards Medicine (Vol. 173, pp. 243-259). Springer. https://doi.org/10.1007/b138836

Paca-Uccaralertkun, S., Damgaard, C. K., Auewarakul, P., Thitithanyanont, A., Suphaphiphat, P., Essex, M., Kjems, J. & Lee, T.-H. (2006). The Effect of a Single Nucleotide Substitution in the Splicing Silencer in the tat/rev Intron on HIV Type 1 Envelope Expression. AIDS Research and Human Retroviruses, 22(1), 76-82. https://doi.org/10.1089/aid.2006.22.76

Kammler, S., Otte, M., Hauber, I., Kjems, J., Hauber, J. & Schaal, H. (2006). The strength of the HIV-1 3' splice sites affects Rev function. Retrovirology, 3(89), 1-20. https://doi.org/10.1186/1742-4690-3-89

Displaying results 386 to 390 out of 440

Full list of publications

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Revised 08.12.2025

Rikke Ploug Frydenberg