Interdisciplinary Nanoscience Center

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 CellPAT STEFFEN THIEL: Innate Immune system

STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Smedbråten, J., Mjøen, G., Hartmann, A., Åsberg, A., Rollag, H., Mollnes, T. E., Sandvik, L., Fagerland, M. W., Thiel, S. & Sagedal, S. (2016). Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients. BMC Nephrology, 17(1), 148. Article 148. https://doi.org/10.1186/s12882-016-0373-9
Banda, N. K., Acharya, S., Scheinman, R. I., Mehta, G., Coulombe, M., Takahashi, M., Sekine, H., Thiel, S., Fujita, T. & Holers, V. M. (2016). Mannan-Binding Lectin-Associated Serine Protease 1/3 Cleavage of Pro-Factor D into Factor D In Vivo and Attenuation of Collagen Antibody-Induced Arthritis through Their Targeted Inhibition by RNA Interference-Mediated Gene Silencing. Journal of Immunology, 197(9), 3680-3694. https://doi.org/10.4049/jimmunol.1600719
Kjaer, T. R., Jensen, L., Hansen, A., Dani, R., Jensenius, J. C., Dobó, J., Gál, P. & Thiel, S. (2016). Oligomerization of mannan-binding lectin dictates binding properties and complement activation. Scandinavian Journal of Immunology, 84(1), 12-19. https://doi.org/10.1111/sji.12441
Ingels, C., Vanhorebeek, I., Derese, I., Jensen, L., Wouters, P. J., Thiel, S. & Van den Berghe, G. (2016). The pattern recognition molecule collectin-L1 in critically ill children. Pediatric Research, 80(2), 237-243. https://doi.org/10.1038/pr.2016.76
Laursen, T. L., Sandahl, T. D., Støy, S., Schiødt, F. V., Lee, W. M., Vilstrup, H., Thiel, S. & Grønbaek, H. (2015). Circulating mannan-binding lectin, M-, L-, H-ficolin and collectin-liver-1 levels in patients with acute liver failure. Liver International, 35(3), 756-63. https://doi.org/10.1111/liv.12682

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Group leader

Postal Address

Interdisciplinary Nanoscience Center (iNANO)

Gustav Wieds Vej 14

8000 Aarhus C

Denmark
Revised 08.12.2025
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Rikke Ploug Frydenberg