Interdisciplinary Nanoscience Center

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 CellPAT STEFFEN THIEL: Innate Immune system

STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Zhang, M., Takahashi, K., Alicot, E. M., Vorup-Jensen, T., Kessler, B., Thiel, S., Jensenius, J. C., Ezekowitz, R. A., Moore, F. D. & Carroll, M. C. (2006). Activation of the lectin pathway by natural IgM in a model of ischemia/reperfusion injury. J. Immunol., 177, 4727-34.
Zhang, J., Koh, J., Lu, J., Thiel, S., Leong, B. S. H., Sethi, S., He, C. Y. X., Ho, B. & Ding, J. L. (2009). Local inflammation induces complement crosstalk which amplifies the antimicrobial response. PLoS Pathogens, 5(1), e1000282. https://doi.org/10.1371/journal.ppat.1000282
Zhang, M., Takahashi, K., Alicot, E. M., Vorup-Jensen, T., Kessler, B., Thiel, S., Jensenius, J. C., Ezekowitz, R. A. B., Moore, F. D. & Carroll, M. C. (2006). Activation of the lectin pathway by natural IgM in a model of ischemia/reperfusion injury. Journal of Immunology, 177(7), 4727-34.
Zarantonello, A., Presumey, J., Simoni, L., Yalcin, E., Fox, R., Hansen, A., Olesen, H. G., Thiel, S., Johnson, M. B., Stevens, B., Laursen, N. S., Carroll, M. C. & Andersen, G. R. (2020). An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase. Journal of Immunology, 205(6), 1678-1694. https://doi.org/10.4049/jimmunol.2000528
Zacho, R. M., Jensen, L., Terp, R., Jensenius, J. C. & Thiel, S. (2012). Studies of the pattern recognition molecule H-ficolin: specificity and purification. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.M111.301044

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Group leader

Postal Address

Interdisciplinary Nanoscience Center (iNANO)

Gustav Wieds Vej 14

8000 Aarhus C

Denmark
Revised 08.12.2025
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Rikke Ploug Frydenberg