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Interdisciplinary Nanoscience Center

CellPAT

STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Bernth Jensen, J. M., Petersen, M. S., Ellerman-Eriksen, S., Møller, B. K., Jensenius, J. C., Sørensen, U. B. S. & Thiel, S. (2020). Abundant human anti-Galα3Gal antibodies display broad pathogen reactivity. Scientific Reports, 10(1), Article 4611. https://doi.org/10.1038/s41598-020-61632-9

Pedersen, H., Jensen, R. K., Hansen, A. G., Gadeberg, T. A. F., Thiel, S., Laursen, N. S. & Andersen, G. (2020). A C3 specific nanobody that blocks all three activation pathways in the human and murine complement system. The Journal of Biological Chemistry, 295(26), 8746-8758. https://doi.org/10.1074/jbc.RA119.012339

Pedersen, H., Jensen, R. K., Jensen, J. M. B., Fox, R., Pedersen, D. V., Olesen, H. G., Hansen, A. G., Christiansen, D., Mazarakis, S. M. M., Lojek, N., Hansen, P., Gadeberg, T. A. F., Zarantonello, A., Laursen, N. S., Mollnes, T. E., Johnson, M. B., Stevens, B., Thiel, S. & Andersen, G. R. (2020). A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity. Journal of Immunology, 205(8), 2287-2300. https://doi.org/10.4049/jimmunol.2000752

Weinschutz Mendes, H., Boldt, A. W., Stahlke, E., Jensenius, J. C., Thiel, S. & Messias-Reason, I. J. T. (2020). Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels. PLOS Neglected Tropical Diseases , 14(4), 1-20. Article e0007534. https://doi.org/10.1371/journal.pntd.0007534

Zarantonello, A., Presumey, J., Simoni, L., Yalcin, E., Fox, R., Hansen, A., Olesen, H. G., Thiel, S., Johnson, M. B., Stevens, B., Laursen, N. S., Carroll, M. C. & Andersen, G. R. (2020). An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase. Journal of Immunology, 205(6), 1678-1694. https://doi.org/10.4049/jimmunol.2000528

Displaying results 61 to 65 out of 511

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Full list of publications

Group leader

Postal Address

Interdisciplinary Nanoscience Center (iNANO)

Gustav Wieds Vej 14

8000 Aarhus C

Denmark

Revised 08.12.2025

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Rikke Ploug Frydenberg