Research

There are three main focus areas of The Scientist's group:

a) The understanding of how small non-coding RNA and circular RNA contribute to cell maintenance and disease development with a primary aim of defining new targets for disease intervention.

b) The creation of novel bioimaging and delivery systems for gene medicine including siRNA, miRNA mimics, antimiRs (antisense targeting microRNA) with a specific focus on inflammation, cancer, influenza, and regeneration of damaged tissue (tissue engineering).

c) Design and construction of functionalized self assembled DNA and RNA nanostructures capable of complex biosensing, coupled with controlled action e.g. drug release, enzyme activation, and receptor signaling.

Recent publications

Sort by: Date | Author | Title

Yu, M., Kalashnyk, N., Barattin, R., Benjalal, Y., Hliwa, M., Bouju, X., Gourdon, A., Heinz, J. C., Laegsgaard, E., Besenbacher, F. & Linderoth, T. R. (2010). Self-assembly of hydrogen-bonded chains of molecular landers. Chemical Communications, 46(30), 5545-7. https://doi.org/10.1039/c0cc01130d

Helmig, S. W., Rotaru, A., Arian, D., Kovbasyuk, L., Arnbjerg, J., Ogilby, P. R., Kjems, J., Mokhir, A., Besenbacher, F. & Gothelf, K. V. (2010). Single Molecule Atomic Force Microscopy Studies of Photosensitized Singlet Oxygen Behavior on a DNA Origami Template. A C S Nano, 4(12), 7475-7480. https://doi.org/10.1021/nn102701f

Voigt, N. V., Tørring, T., Rotaru, A., Jacobsen, M. F., Ravnsbæk, J. B., Subramani, R., Mamdouh, W., Kjems, J., Mokhir, A., Besenbacher, F. & Gothelf, K. V. (2010). Single-molecule chemical reactions on DNA origami. Nature Nanotechnology, 5(3), 200-203. https://doi.org/10.1038/nnano.2010.5

Andersen, M. Ø., Nygaard, J. V., Burns, J. S., Raarup, M. K., Nyengaard, J. R., Bünger, C., Besenbacher, F., Howard, K. A., Kassem, M. & Kjems, J. (2010). siRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells. Molecular Therapy, 18(11), 2018-2027. https://doi.org/10.1038/mt.2010.166

Tuxen, A. K., Kibsgaard, J., Gøbel, H. T., Lægsgaard, E., Topsøe, H., Besenbacher, F. & Lauritsen, J. V. (2010). Size Threshold in the Dibenzothiophene Adsorption on MoS2 Nanoclusters. A C S Nano, 4(8), 4677-4682. https://doi.org/10.1021/nn1011013

Displaying results 376 to 380 out of 904

Group leader

Group members

Full list of publications

Revised 08.12.2025

Lise Refstrup Linnebjerg Pedersen