Andersen, E. S., Dong, M., Nielsen, M. M., Jahn, K., Subramani, R., Mamdouh, W., Golas, M. M., Sander, B., Stark, H.
, Oliveira, C. L. P., Pedersen, J. S., Birkedal, V., Besenbacher, F., Gothelf, K. V. & Kjems, J. (2009).
Self-assembly of a nanoscale DNA box with a controllable lid.
Nature,
459(7243), 73-6.
https://doi.org/10.1038/nature07971
Jahn, K., Nielsen, M. M., Olsen, E. M., Mohammadzadegan, R.
, Andersen, E. S., Gothelf, K. V. & Kjems, J. (2009).
Site-specific labeling of long HIV-1 RNA using DNA templated chemistry. 84-88. Paper presented at 6th Annual Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2009, Snowbird, UT, United States.
Larsen, E. K. U., Nielsen, T., Wittenborn, T., Birkedal, H., Vorup-Jensen, T., Jakobsen, M. H.
, Østergaard, L., Horsman, M. R., Besenbacher, F., Howard, K. A. & Kjems, J. (2009).
Size-Dependent Accumulation of PEGylated Silane-Coated Magnetic Iron Oxide Nanoparticles in Murine Tumors.
A C S Nano,
3(7), 1947-51.
https://doi.org/10.1021/nn900330m
Gao, S., Dagnæs-Hansen, F., Nielsen, E. J. B., Wengel, J.
, Besenbacher, F., Howard, K. A. & Kjems, J. (2009).
The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice.
Molecular Therapy,
17(7), 1225-1233.
https://doi.org/10.1038/mt.2009.91
Damgaard, C. K., Kahns, S., Lykke-Andersen, S., Nielsen, A. L., Jensen, T. H. & Kjems, J. (2008).
A 5' splice site enhances the recruitment of basal transcription initiation factors in vivo.
Molecular Cell,
29(2), 271-278.
https://doi.org/10.1016/j.molcel.2007.11.035
Damgaard, C. K., Kahns, S., Lykke-Andersen, S., Nielsen, A. L., Jensen, T. H. & Kjems, J. (2008).
A 5' splice site enhances the recruitment of basal transcription initiation factors in vivo.
Molecular Cell,
29(2), 271-8.
https://doi.org/10.1016/j.molcel.2007.11.035
Howard, K. A., Paludan, S. R., Behlke, M. A.
, Besenbacher, F., Deleuran, B. W. & Kjems, J. (2008).
Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model.
Molecular Therapy,
17(1), 162-168.
https://doi.org/10.1038/mt.2008.220
Torarinsson, E., Yao, Z.
, Wiklund, E. D., Bramsen, J. B., Hansen, C. A.
, Kjems, J., Tommerup, N., Ruzzo, W. L. & Gorodkin, J. (2008).
Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions.
Genome Research,
18(2), 242-251.
https://doi.org/10.1101/gr.6887408
Andersen, M. Ø., Howard, K. A., Paludan, S. R., Besenbacher, F. & Kjems, J. (2008).
Delivery of siRNA from lyophilized polymeric surfaces.
Biomaterials,
29(4), 506-512.
https://doi.org/10.1016/j.biomaterials.2007.10.003
Andersen, E. S., Dong, M., Nielsen, M. M., Jahn, K., Lind-Thomsen, A.
, Mamdouh, W., Gothelf, K. V., Besenbacher, F. & Kjems, J. (2008).
DNA origami design of dolphin-shaped structures with flexible tails.
A C S Nano,
2(6), 1213-8.
https://doi.org/10.1021/nn800215j
Rahbek, U. L., Howard, K. A., Oupicky, D., Manickam, D. S.
, Dong, M., Nielsen, A. F., Hansen, T. B., Besenbacher, F. & Kjems, J. (2008).
Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides.
Journal of Gene Medicine,
10(1), 81-93.
https://doi.org/10.1002/jgm.1120
Nygaard, J. V., Andersen, M. Ø., Howard, K. A., Foss, M., Bünger, C., Kjems, J. & Besenbacher, F. (2008).
Investigation of particle-functionalized tissue engineering scaffolds using X-ray tomographic microscopy.
Biotechnology and Bioengineering (Print),
100(4), 820-9.
https://doi.org/10.1002/bit.21796
Nygaard, J. V., Andersen, M. Ø., Cloetens, P.
, Foss, M., Kassem, M.
, Kjems, J. & Besenbacher, F. (2008).
Nanoscaffolds for Drug Delivery and Tissue Engineering. Poster session presented at iNANO 6
th annual meeting, Aarhus, Denmark.
Astakhova, I., Korshun, V. A.
, Jahn, K., Kjems, J. & Wengel, J. (2008).
Perylene attached to 2'-amino-LNA: synthesis, incorporation into oligonucleotides, and remarkable fluorescence properties in vitro and in cell culture.
Bioconjugate Chemistry,
19(10), 1995-2007.
https://doi.org/10.1021/bc800202v
Skivesen, N., Tetu, A., Kristensen, M., Kjems, J., Frandsen, L. H. & Borel, P. I. (2008).
Protein detection with a planar photonic-crystal sensor. Paper presented at CLEO-EU, Munich, Germany.
Andersen, E. S., Nielsen, M. M., Dong, M., Besenbacher, F., Kjems, J. & Gothelf, K. V. (2008).
Software package for the design and analysis of DNA origami structures. Paper presented at FNANO 2008, Snowbird, United States.
Otero Martin, R., Xu, W., Lukas, M., Kelly, R. E. A.
, Laegsgaard, E., Stensgaard, I., Kjems, J., Kantorovich, L. N.
& Besenbacher, F. (2008).
Specificity of Watson-Crick Base Pairing on a Solid Surface Studied at the Atomic Scale.
Angewandte Chemie,
47(50), 9673-9676.
https://doi.org/10.1002/anie.200803333
Odadzic, D.
, Bramsen, J. B., Smicius, R.
, Bus, C., Kjems, J. & Engels, J. W. (2008).
Synthesis of 2'-O-modified adenosine building blocks and application for RNA interference.
Bioorganic & Medicinal Chemistry,
16(1), 518-529.
https://doi.org/10.1016/j.bmc.2007.09.019
Xu, S., Dong, M., Liu, X., Howard, K. A., Kjems, J. & Besenbacher, F. (2007).
Direct force measurements between siRNA and chitosan molecules using force spectroscopy.
Biophysical Journal,
93(3), 952-9.
https://doi.org/10.1529/biophysj.106.093229
Jakobsen, M. R., Haasnoot, J., Wengel, J., Berkhout, B.
& Kjems, J. (2007).
Efficient inhibition of HIV-1 expression by LNA modified antisense oligonucleotides and DNAzymes targeted to functionally selected binding sites.
Retrovirology,
4(29), 1-13.
https://doi.org/10.1186/1742-4690-4-29
Bramsen, J. B., Laursen, M. B., Damgaard, C. K., Lena, S. W., Babu, B. R., Wengel, J.
& Kjems, J. (2007).
Improved silencing properties using small internally segmented interfering RNAs.
Nucleic Acids Research,
35(17), 5886-5897.
https://doi.org/10.1093/nar/gkm548
Skivesen, N., Kristensen, M., Kjems, J., Frandsen, L. H., Borel, P. I.
& Tetu, A. (2007).
Metal-clad waveguides anvendt som optiske bio-sensorer.
D O P S - Nyt,
07(1), 20.
Howard, K. A., Dong, M., Oupicky, D., Bisht, H. S., Buss, C.
, Besenbacher, F. & Kjems, J. (2007).
Nanocarrier stimuli-activated gene delivery.
Small,
3(1), 54-7.
https://doi.org/10.1002/smll.200600328
Skivesen, N., Têtu, A., Kristensen, M., Kjems, J., Frandsen, L. H. & Borel, P. I. (2007).
Photonic-crystal waveguide biosensor.
Optics Express,
15(6), 3169-3176.
Skivesen, N., Tetu, A., Kristensen, M., Kjems, J., Frandsen, L. H. & Borel, P. I. (2007).
Planar photonic crystal waveguide biosensor. Poster session presented at ECIO, København, Denmark.
Nielsen, K. B., Sørensen, S., Cartegni, L.
, Corydon, T. J., Doktor, T. K., Schroeder, L. D., Reinert, L. S., Elpeleg, O., Krainer, A. R.
, Gregersen, N., Kjems, J. & Andresen, B. S. (2007).
Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations: a synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a flanking exonic splicing enhancer.
American Journal of Human Genetics,
80(3), 416-432.
https://doi.org/10.1086/511992
Andersen, E. S., Lind-Thomsen, A., Knudsen, B., Kristensen, S. E., Havgaard, J. H., Torarinsson, E., Larsen, N., Zwieb, C., Sestoft, P.
, Kjems, J. & Gorodkin, J. (2007).
Semiautomated improvement of RNA alignments.
RNA,
13, 1850-1859.
Andersen, M. Ø., Nygaard, J. V., Howard, K., Bak, R. O., Paludan, S. R., Raarup, M. K., Besenbacher, F. & Kjems, J. (2007).
Surface delivery of siRNA for implants.
European Cells & Materials,
14(3), 118.
Liu, X., Howard, K. A., Dong, M., Andersen, M. Ø., Rahbek, U. L., Johnsen, M. G., Hansen, O. C.
, Besenbacher, F. & Kjems, J. (2007).
The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing.
Biomaterials,
28(6), 1280-8.
https://doi.org/10.1016/j.biomaterials.2006.11.004
Novotny, G. W., Sonne, S.
, Nielsen, J. E., Jonstrup, S. P., Hansen, M. A., Skakkebaek, N. E., Rajpert-De Meyts, E.
, Kjems, J. & Leffers, H. (2007).
Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster.
Cell Death and Differentiation,
14(4), 879-882.
https://doi.org/10.1038/sj.cdd.4402090
Dong, M., Howard, K. A., Oupicky, D., Bisht, H. J.
, Kjems, J. & Besenbacher, F. (2007).
Visualisation of Thermal Activated Nanocarriers Using In Situ Atomic Force Microscopy.
Nanotechnology.
Dong, M. D., Howard, K. A., Oupicky, D., Bisht, H.
, Kjems, J. & Besenbacher, F. (2007).
Visualization of thermally activated nanocarriers using in situ atomic force microscopy: Nanotechnology.
Nanotechnology,
18(18), Article 185501.
https://doi.org/10.1088/0957-4484/18/18/185501
Lützelberger, M., Reinert, L. S., Das, A. T., Berkhout, B.
& Kjems, J. (2006).
A novel splice donor site in the gag-pol gene is required for HIV-1 RNA stability.
Journal of Biological Chemistry,
281(27), 18644-18651.
https://doi.org/10.1074/jbc.M513698200
Mohey, R., Katzenstein, T. L.
, Black, F. T., Kjems, J. & Obel, N. (2006).
Dynamics of proviral HIV-1 184M/V in circulating CD4+ T-cells: a 90 days follow-up study after initiation/switch of HAART.
Scandinavian Journal of Infectious Diseases,
38(2), 119-123.
https://doi.org/10.1080/00365540500348937
Mohey, R., Tolstrup, M., Jørgensen, L. B.
, Møller, B. K., Black, F. T., Kjems, J. & Obel, N. (2006).
HIV-1 reverse Transcriptase Gene 103K/N and 184M/V Combinations in Tandem: Detection and Quantification of HIV-1 Populations in the CD45RO+ T-cell Compartment by a Double-ARMS Real-Time PCR assay.
J A I D S,
41(2), 160-167.
https://doi.org/10.1097/01.qai.0000191998.70034.64
Howard, K. A., Rahbek, U. L., Liu, X., Damgaard, C. K., Glud, S. Z., Andersen, M. Ø., Hovgaard, M. B., Schmitz, A., Nyengaard, J. R., Besenbacher, F. & Kjems, J. (2006).
RNA interference in Vitro and in Vivo using a novel chitosan/siRNA nanoparticle system.
Molecular Therapy,
14(4), 476-484.
https://doi.org/10.1016/j.ymthe.2006.04.010