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Effect of Optimization of Glycaemic Control on Mannan-Binding Lectin in Type 1 Diabetes.
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Endogenous Natural Complement Inhibitor Regulates Cardiac Development.
Journal of Immunology,
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Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism.
Frontiers in Immunology,
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Ficolin-1 Levels in Patients Developing Vasospasm and Cerebral Ischemia After Spontaneous Subarachnoid Hemorrhage.
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Functional and structural insight into properdin control of complement alternative pathway amplification.
E M B O Journal,
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Global Autorecognition and Activation of Complement by Mannan-Binding Lectin in a Mouse Model of Type 1 Diabetes.
Mediators of Inflammation,
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Incident microalbuminuria and complement factor mannan-binding lectin-associated protein 19 in people with newly diagnosed type 1 diabetes.
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Lectin Complement Pathway Plasma Levels in IgA Nephropathy. Molecular Immunology SI: EMCHD2017 Vol 89 2017..
Troldborg, A., Hansen, A. G., Hansen, S. W. K.
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Lectin Complement Pathway Proteins in Healthy Individuals.
Clinical and Experimental Immunology,
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Lectin Pathway Proteins and association to Systemic Lupus Erythematosus.Troldborg. Molecular Immunology SI: EMCHD2017 Vol 89 2017..
Jensen, K., Lund, K. P., Christensen, K. B.
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M-ficolin is present in Aspergillus fumigatus infected lung and modulates epithelial cell immune responses elicited by fungal cell wall polysaccharides.
Virulence,
8(8), 1870-1879.
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Plasma levels of MASP-1, MASP-3 and MAp44 in patients with type 2 diabetes - influence of glycaemic control, body composition and polymorphisms in the MASP1 gene.
Clinical and Experimental Immunology,
189(1), 103-112.
https://doi.org/10.1111/cei.12963
Mortensen, S. A., Sander, B., Jensen, R. K., Pedersen, J. S., Golas, M., Jensenius, J. C., Hansen, A. G., Thiel, S. & Andersen, G. R. (2017).
Reply to Arlaud et al. Structure of the C1 complex and the unbound C1r2s2 tetramer.
Proceedings of the National Academy of Sciences (PNAS),
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Pedersen, D. V., Roumenina, L.
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Structural and functional studies of human complement factor P.
Molecular Immunology,
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Structure and activation of C1, the complex initiating the classical pathway of the complement cascade.
Proceedings of the National Academy of Sciences (PNAS),
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Haugaard, S., Nørgaard Jeppesen, A.
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The complement lectin pathway in post cardiac arrest patients: a randomised clinical study. Res Pract Thromb Haemost. 2017;1(Suppl. 1):1–1451..
Troldborg, A., Thiel, S., Trendelenburg, M., Friebus-Kardash, J., Nehring, J., Steffensen, R., Hansen, S. W. K.
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The Lectin Pathway of the Complement System is Activated in Patients with Systemic Lupus Erythematosus.. Arthritis Rheumatol. 2017 Oct;69 Suppl 10:1-4426..
Osthoff, M., Wojtowicz, A., Tissot, F.
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Association of lectin pathway proteins with intra-abdominal Candida infection in high-risk surgical intensive-care unit patients. A prospective cohort study within the fungal infection network of Switzerland.
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Complement activation evaluated by measurement of C3dg - A new assay and results from measurements in patients with SLE. Immunobiology Volume 221, Issue 10, Pages 1035-1226 2016.
Banda, N. K., Acharya, S., Scheinman, R. I., Mehta, G., Takahashi, M.
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Complement mannan-binding lectin associated serine proteases 1 and 3 generated by allo-liver transplantation cleave in vivo pro-Factor D generated by the adipose tissue into active Factor D.
Journal of Immunology,
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Hertle, E., Arts, I. C. W., Van Der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G.
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Distinct longitudinal associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 with endothelial dysfunction and intima-media thickness.
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Heparin and the lectin pathway in lung cancer patients undergoing surgery. Immunobiology Volume 221, Issue 10, Pages 1035-1226.
Østergaard, J. A., Ruseva, M. M., Malik, T. H.
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Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model.
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Influence of mannan-binding lectin and MAp44 on outcome in comatose survivors of out-of-hospital cardiac arrest.
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Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients.
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Mannan-Binding Lectin-Associated Serine Protease 1/3 Cleavage of Pro-Factor D into Factor D In Vivo and Attenuation of Collagen Antibody-Induced Arthritis through Their Targeted Inhibition by RNA Interference-Mediated Gene Silencing.
Journal of Immunology,
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Oligomerization of mannan-binding lectin dictates binding properties and complement activation.
Scandinavian Journal of Immunology,
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Ingels, C., Vanhorebeek, I., Derese, I.
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The pattern recognition molecule collectin-L1 in critically ill children.
Pediatric Research,
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Circulating mannan-binding lectin, M-, L-, H-ficolin and collectin-liver-1 levels in patients with acute liver failure.
Liver International,
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CL-L1 and CL-K1 and other complement associated pattern recognition molecules in systemic lupus erythematosus.
Clinical and Experimental Immunology.
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CL-L1 and CL-K1 – Pattern Recognition Molecules of the Lectin Pathway form Heterocomplexes, and are Associated with other Complement Proteins and Disease Manifestations in Systemic Lupus Erythematosus.. Arthritis Rheumatol. 2015 Oct;67 Suppl 10:1-4046.
Bajic, G., Degn, S. E., Thiel, S. & Andersen, G. R. (2015).
Complement activation, regulation, and molecular basis for complement-related diseases.
E M B O Journal,
34(22), 2735-2757.
https://doi.org/10.15252/embj.201591881
Storm, L., Christensen, I. J.
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Evaluation of complement proteins as screening markers for colorectal cancer.
Cancer Immunology, Immunotherapy,
64(1), 41-50.
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Ficolin B in Diabetic Kidney Disease in a Mouse Model of Type 1 Diabetes.
Mediators of Inflammation,
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Bayarri-Olmos, R., Hansen, S., Henriksen, M. L.
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Genetic variation of COLEC10 and COLEC11 and association with serum levels of collectin liver 1 (CL-L1) and collectin kidney 1 (CL-K1).
PLOS ONE,
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& Thiel, S. (2015).
High ficolin-3 level at the time of transplantation is an independent risk factor for graft loss in kidney transplant recipients.
Transplantation,
99(4), 791-6.
https://doi.org/10.1097/TP.0000000000000422Østergaard, J. A., Thiel, S., Lajer, M.
, Steffensen, R., Parving, H.-H.
, Flyvbjerg, A., Rossing, P.
, Tarnow, L. & Hansen, T. K. (2015).
Increased All-Cause Mortality in Patients With Type 1 Diabetes and High-Expression Mannan-Binding Lectin Genotypes: A 12-Year Follow-up Study.
Diabetes Care,
38(10), 1898-1903.
https://doi.org/10.2337/dc15-0851
Troldborg, A., Thiel, S., Laska, M. J., Deleuran, B., Jensenius, J. C. & Stengaard-Pedersen, K. (2015).
Levels in plasma of the serine proteases and associated proteins of the lectin pathway are altered in patients with systemic lupus erythematosus.
Journal of Rheumatology,
42(6), 948-51.
https://doi.org/10.3899/jrheum.141163
Atik, T., Koparir, A., Bademci, G., Foster, J., Altunoglu, U., Mutlu, G. Y., Bowdin, S., Elcioglu, N., Tayfun, G. A., Atik, S. S., Ozen, M., Ozkinay, F., Alanay, Y., Kayserili, H.
, Thiel, S. & Tekin, M. (2015).
Novel MASP1 mutations are associated with an expanded phenotype in 3MC1 syndrome.
Orphanet Journal of Rare Diseases,
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, Thiel, S. & Schroeder, V. (2015).
Plasma levels of mannan-binding lectin-associated serine proteases MASP-1 and MASP-2 are elevated in type 1 diabetes and correlate with glycaemic control.
Clinical and Experimental Immunology,
180(2), 227-32.
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Plasma levels of the serine proteases and associated proteins of the Lectin Pathway are altered in SLE patients.
Molecular Immunology,
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Kjaer, T. R., Le, L. T. M., Pedersen, J. S., Sander, B., Golas, M. M., Jensenius, J. C., Andersen, G. R. & Thiel, S. (2015).
Structural Insights into the Initiating Complex of the Lectin Pathway of Complement Activation.
Structure,
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Holt, C. B., Thiel, S., Munk, K., Østergaard, J. A., Bøtker, H. E. & Hansen, T. K. (2014).
Association between endogenous complement inhibitor and myocardial salvage in patients with myocardial infarction.
European Heart Journal: Acute Cardiovascular Care,
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Østergaard, J. A., Thiel, S., Hovind, P.
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& Hansen, T. K. (2014).
Association of the pattern recognition molecule H-ficolin with incident microalbuminuria in an inception cohort of newly diagnosed type 1 diabetic patients: an 18 year follow-up study.
Diabetologia,
57(10), 2201-7.
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Foldager, L., Köhler, K. O., Steffensen, R. N., Thiel, S., Kristensen, A. S., Jensenius, J. C. & Mors, O. (2014).
Bipolar and panic disorders may be associated with hereditary defects in the innate immune system.
Journal of Affective Disorders,
164, 148-154.
https://doi.org/10.1016/j.jad.2014.04.017
Kelsen, J., Sandahl, T. D., Storm, L., Frings-Meuthen, P.
, Dahlerup, J. F. & Thiel, S. (2014).
Changes in the levels of mannan-binding lectin and ficolins during head-down tilted bed rest.
Aviation, Space, and Environmental Medicine,
85(8), 805-11.
https://doi.org/10.3357/ASEM.3915.2014
Degn, S. E., Kjaer, T. R., Kidmose, R. T., Jensen, L., Hansen, A. G., Tekin, M.
, Jensenius, J. C., Andersen, G. R. & Thiel, S. (2014).
Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes.
Proceedings of the National Academy of Sciences (PNAS),
111(37), 13445-13450.
https://doi.org/10.1073/pnas.1406849111
Schlapbach, L. J.
, Thiel, S., Aebi, C., Hirt, A., Leibundgut, K.
, Jensenius, J. C. & Ammann, R. A. (2014).
Corrigendum to M-ficolin in children with cancer [Immunobiology 216, (2011), 633-638] DOI: 10.1016/j.imbio.2010.09.013.
Immunobiology,
219(12), 990-991.
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