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Interdisciplinary Nanoscience Center

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STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Bernth Jensen, J. M., Laursen, N. S., Kjeldsen Jensen, R., Andersen, G. R., Jensenius, J. C., Skov Sørensen, U. B. & Thiel, S. (2020). Complement activation by human IgG antibodies to galactose-α-1,3-galactose. Immunology, 161(1), 66-79. https://doi.org/10.1111/imm.13229

Troldborg, A., Halkjær, L., Pedersen, H., Hansen, A., Loft, A. G., Lindegaard, H., Stengaard-Pedersen, K., Graversen, J. H., Palarasah, Y. & Thiel, S. (2020). Complement activation in human autoimmune diseases and mouse models; employing a sandwich immunoassay specific for C3dg. Journal of Immunological Methods, 486, Article 112866. https://doi.org/10.1016/j.jim.2020.112866

Halkjær, L., Troldborg, A., Pedersen, H., Jensen, L., Hansen, A. G., Krarup Hansen, T., Bjerre, M., Østergaard, J. A. & Thiel, S. (2020). Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-level in Plasma Samples from Mice and Humans. Frontiers in Immunology, 11, Article 774. https://doi.org/10.3389/fimmu.2020.00774

Laursen, N. S., Pedersen, D. V., Gytz, H., Zarantonello, A., Bernth Jensen, J. M., Hansen, A. G., Thiel, S. & Andersen, G. R. (2020). Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System. Frontiers in Immunology, 11, Article 1504. https://doi.org/10.3389/fimmu.2020.01504

Holers, V. M., Borodovsky, A., Scheinman, R. I., Ho, N., Ramirez, J. R., Dobó, J., Gál, P., Lindenberger, J., Hansen, A. G., Desai, D., Pihl, R., Thiel, S. & Banda, N. K. (2020). Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D. Frontiers in Immunology, 11, Article 201. https://doi.org/10.3389/fimmu.2020.00201

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Full list of publications

Group leader

Postal Address

Interdisciplinary Nanoscience Center (iNANO)

Gustav Wieds Vej 14

8000 Aarhus C

Denmark

Revised 08.12.2025

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Rikke Ploug Frydenberg