STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Møller-Kristensen, M., Thiel, S., Hansen, A. G. & Jensenius, J. C. (2003). On the site of C4 deposition upon complement activation via the mannan-binding lectin pathway or the classical pathway. Scandinavian Journal of Immunology, 57(6), 556-61.

Larkin, M., Childs, R. A., Matthews, T. J., Thiel, S., Mizuochi, T., Lawson, A. M., Savill, J. S., Haslett, C., Diaz, R. & Feizi, T. (1989). Oligosaccharide-mediated interactions of the envelope glycoprotein gp120 of HIV-1 that are independent of CD4 recognition. AIDS, 3(12), 793-8.

Kjaer, T. R., Jensen, L., Hansen, A., Dani, R., Jensenius, J. C., Dobó, J., Gál, P. & Thiel, S. (2016). Oligomerization of mannan-binding lectin dictates binding properties and complement activation. Scandinavian Journal of Immunology, 84(1), 12-19. https://doi.org/10.1111/sji.12441

Atik, T., Koparir, A., Bademci, G., Foster, J., Altunoglu, U., Mutlu, G. Y., Bowdin, S., Elcioglu, N., Tayfun, G. A., Atik, S. S., Ozen, M., Ozkinay, F., Alanay, Y., Kayserili, H., Thiel, S. & Tekin, M. (2015). Novel MASP1 mutations are associated with an expanded phenotype in 3MC1 syndrome. Orphanet Journal of Rare Diseases, 10, 128. https://doi.org/10.1186/s13023-015-0345-3

Schack, V. R., Herlin, M. K., Pedersen, H., Jensen, J. M. B., Faerch, M., Bundgaard, B., Jensen, R. K., Jensen, U. B., Christensen, R., Andersen, G. R., Thiel, S. & Höllsberg, P. (2022). Novel homozygous CD46 variant with C-isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome. European Journal of Immunology, 52(10), 1610-1619. https://doi.org/10.1002/eji.202249838

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Full list of publications

Group leader

Group members

Postal Address

Interdisciplinary Nanoscience Center (iNANO)

Gustav Wieds Vej 14

8000 Aarhus C

Denmark

Revised 08.12.2025

Rikke Ploug Frydenberg