Researchers from the Gothelf lab has recently published a mini review in ChemBioChem on how to design probes for affinity guided protein conjugation. This labelling method is based on non-covalent binding interaction between the protein of interest and the probe. The mini review presents the latest progress in the field of affinity guided protein conjugation in terms of both formation of high-quality protein conjugates and labelling in living systems.

Read the full article "Consideration on Probe Design for Affinity Guided Protein Conjugation" on the ChemBioChem website