PAPER: Synthesis and biophysical properties of (l)-aTNA based G-quadruplexes
![Screenshot from the article "synthesis and biophysical proterties of (L)-aTNA based G-quadruplexes" published in Organic & Biomolecular Chemistry Screenshot from the article "synthesis and biophysical proterties of (L)-aTNA based G-quadruplexes" published in Organic & Biomolecular Chemistry](/fileadmin/news_import/Screenshot_from_the_article__22synthesis_and_biophysical_proterties_of__L_-aTNA_based_G-quadruplexes_22_published_in_Organic___Biomolecular_Chemistry.png)
Org Biomol Chem. 2016, doi: 10.1039/c5ob02525g
Kumar V, Gothelf KV
Danish National Research Foundation Center for DNA Nanotechnology, iNANO, , Aarhus University, 8000 Aarhus C, Denmark
Department of Chemistry, Aarhus University, 8000 Aarhus C, Denmark
Abstract
Novel G-quadruplex structures are constructed by acyclic (l)-threninol nucleic acid and their synthesis and biophysical properties are described. Pyrene excimer fluorescence and circular dichroism (CD) data revealed that four strands of aTNA are oriented in antiparallel direction.