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CANCELLED - Distinguished iNANO & Chemistry Lecture: Translational Chemical Biology

Dr. Gonçalo J. L. Bernardes | Reader in Chemical Biology Department of Chemistry, University of Cambridge, UK

2021.02.15 | Trine Møller Hansen

Date Fri 19 Mar
Time 10:15 11:00
Location Online via Zoom

Dr. Gonçalo J. L. Bernardes | Reader in Chemical Biology
Department of Chemistry, University of Cambridge, UK

 

Translational Chemical Biology

Our research uses chemistry principles to address questions of importance in life sciences and molecular medicine. This lecture will cover recent examples of i) bioorthogonal cleavage reactions that our group developed and applied for targeted drug activation in cells and animals, ii) new site-specific protein modification reactions and their use to engineer antibodies and finally iii) a small-molecule targeted RNA degradation approach and its use to empower RNA methylation analysis.

Gonçalo Bernardes: After completing his D.Phil. in 2008 at the University of Oxford, U.K., he undertook postdoctoral work at the Max-Planck Institute of Colloids and Interfaces, Germany, and the ETH Zürich, Switzerland, and worked as a Group Leader at Alfama Lda in Portugal. He started his independent research career in 2013 at the University of Cambridge as a Royal Society University Research Fellow. In 2018 he was appointed University Lecturer (Tenured) and recently has been promoted to Reader (Associate Professor). Gonçalo is the recipient of two European Research Council grants; a starting grant and a proof-of-concept grant, and was awarded the Harrison–Meldola Memorial Prize in 2016 and the MedChemComm Emerging Investigator Lectureship in 2018, both from the Royal Society of Chemistry, and more recently the 2020 International Chemical Biology Society Award. His research group interests focus on the use of chemistry principles to tackle challenging biological problems for understanding and fight cancer. He is also an entrepreneur, and has co-founded Targ.Tex, a company that is developing a highly-targeted therapy for the treatment of glioblastoma multiforme.


Host:
Professor Kurt Vesterager Gothelf, iNANO & Dept. of Chemistry


Distinguished iNANO Lectures