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Distinguished iNANO Lecture: Exploiting the human peptidome for novel anti- (and pro-) viral compounds

Professor Dr. Jan Münch, Ulm University Medical Center, Ulm, Germany

Info about event

Time

Friday 6 November 2015,  at 10:15 - 11:00

Location

iNANO Auditorium (1593-012), Gustav Wieds Vej 14, 8000 Aarhus C

Professor Dr. Jan Münich
 

Prof. Dr. Jan Münch, Institute of Molecular Virology, Ulm University Medical Center, U-PEP, Ulm, Germany

Exploiting the human peptidome for novel anti- (and pro-) viral compounds

Almost all human proteins are subject to proteolytic degradation, which produces a broad range of peptides that have highly specific and sometimes unexpected functions. Peptide libraries that have been generated from human bodily fluids or tissues are a rich but mostly unexplored source of bioactive compounds that could be used to develop antimicrobial and immunomodulatory therapeutic agents. In my talk I will describe the discovery, optimization and application of endogenous bioactive peptides from human-derived peptide libraries, with a particular focus on the isolation of endogenous inhibitors and promoters of HIV 1 infection.

  Host: Associate professor Alexander Zelikin, iNANO & Department of Chemistry, Aarhus University