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Distinguished iNANO Lecture: Lead Identification in Drug Research

Section Head Hans Peter Wessel, Infrastructure and Administration, F.Hoffmann-La Roche Ltd in Basel, Switzerland

Info about event

Time

Friday 4 April 2014,  at 10:15 - 11:00

Location

The auditorium of the iNANO House (1593-012), Gustav Wieds Vej 14, 8000 Aarhus C

 

Section Head Hans Peter Wessel, Infrastructure and Administration, F.Hoffmann-La Roche Ltd in Basel, Switzerland

Lead Identification in Drug Research 

Lead Identification is the important stage in the long drug research and development path from concept to market in which the basic chemical structures of a project will be determined. While historically drug candidates were solely derived from natural product isolates, modern drug research relies largely on screening of compound libraries of different origin. Various routes to chemical and virtual library constructions as well as screening techniques including DNA-encoded library technology will be discussed, garnished with practical research examples from experience at F. Hoffmann-La Roche, Basel, Switzerland. On the other hand, mimetics approaches have been successful as exemplified by the development of agents against viral infections.

Host: Professor Troels Skrydstrup, iNANO & Department of Chemistry, Aarhus University

 

Coffee, tea and bread will be served in front of the iNANO auditorium from 10:00.