Zhang, Z., Olsen, E. M., Kryger, M., Voigt, N. V., Tørring, T., Gültekin, E.
, Nielsen, M., MohammadZadegan, R., Andersen, E. S., Nielsen, M. M., Kjems, J., Birkedal, V. & Gothelf, K. V. (2011).
A DNA tile actuator with eleven discrete states.
Angewandte Chemie International Edition,
50(17), 3983-7.
https://doi.org/10.1002/anie.201007642
Wiklund, E. D., Bramsen, J. B., Hulf, T.
, Andersen, L. D., Ramanathan, R., Hansen, T. B., Villadsen, S. B., Gao, S., Ostenfeld, M. S., Borre, M., Peter, M. E.
, Ørntoft, T. F., Kjems, J. & Clark, S. J. (2011).
Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer.
International Journal of Cancer,
128(6), 1327-1334.
https://doi.org/10.1002/ijc.25461
Jahn, K., Tørring, T., Voigt, N. V., Sørensen, R. S., Kodal, A. L. B., Andersen, E. S., Gothelf, K. V. & Kjems, J. (2011).
Functional Patterning of DNA Origami by Parallel Enzymatic Modification.
Bioconjugate Chemistry,
22(4), 819-823.
https://doi.org/10.1021/bc2000098
Krüger, A. C., Nielsen, M. M., Kjems, J., Besenbacher, F. & Birkedal, V. (2011).
G-quadruplex structures in telomeric DNA studied with single molecule FRET microscopy. Poster session presented at Third International Meeting on G-Quadruplex and G-assembly, Sorrento, Italy.
http://f1000.com/posters/browse?conferenceId=297
Yu, M.
, Wang, J., Mura, M., Meng, Q.-Q.
, Xu, W., Gersen, H., Lægsgaard, E., Stensgaard, I., Kelly, R. E. A.
, Kjems, J., Linderoth, T. R., Kantorovich, L. N.
& Besenbacher, F. (2011).
Homochiral Xanthine Quintet Networks Self-Assembled on Au(111) Surfaces.
ACS Nano,
5(8), 6651-6660.
https://doi.org/10.1021/nn202157mWiklund, E. D., Gao, S., Hulf, T., Sibbritt, T., Nair, S., Costea, D. E.
, Villadsen, S. B., Bakholdt, V.
, Bramsen, J. B., Sorensne, J. A., Krogdahl, A., Clark, S. J.
& Kjems, J. (2011).
MicroRNA Alterations and Associated Aberrant DNA Methylation Patterns across Multiple Sample Types in Oral Squamous Cell Carcinoma.
P L o S One,
61(1), e27840 (1-11).
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0027840
Hua, Y., Duan, S., Murmann, A. E.
, Larsen, N., Kjems, J., Lund, A. H. & Peter, M. E. (2011).
miRConnect:Identifying effector genes of miRNAs and miRNA families in cancer cells.
P L o S One,
6(10), e26521.
https://doi.org/10.1371/journal.pone.0026521Hansen, T. B., Wiklund, E. D., Bramsen, J. B., Villadsen, S. B., Statham, A. L., Clark, S. J.
& Kjems, J. (2011).
miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA.
E M B O Journal,
30(21), 4414-4422.
https://doi.org/10.1038/emboj.2011.359
Hoffmann, N., Mittnacht, U., Hartmann, H., Baumer, Y.
, Kjems, J., Oberhoffner, S. & Schlosshauer, B. (2011).
Neuronal and glial responses to siRNA-coated nerve guide implants in vitro.
Neuroscience Letters,
494(1), 14-8.
https://doi.org/10.1016/j.neulet.2011.02.043Le, D. Q. S., Andersen, M. Ø., Baatrup, A., Chen, M., Chen, M., Lysdahl, H., Besenbacher, F., Bünger, C. & Kjems, J. (2011).
Process for Modifying the Surface Morphology of a Medical Device: PA 2011 70752.
Dupont, D. M., Madsen, J. B., Bøtkjær, K. A., Tavitian, B., Duconge, F.
, Kjems, J. & Andreasen, P. (2011).
RNA aptamers to the cancer-associated proteins UPA and PAI-1 with therapeutic potential.
Nucleic Acid Therapeutics,
21(5).
Jepsen, M. B., Beerens, N., Nechyponuk-Zloy, V., Besenbacher, F., Kjems, J. & Birkedal, V. (2011).
Single molecule FRET microscopy studies of tRNA annealing onto the HIV-1 genome. Poster session presented at International Bunsen Discussion Meeting Förster resonance energy transfer in life science, Germany.
Birkedal, V., Dong, M., Golas, M. M., Sander, B., Andersen, E. S., Gothelf, K. V., Besenbacher, F. & Kjems, J. (2011).
Single molecule microscopy methods for the study of DNA origami structures.
Microscopy Research and Technique,
74(7), 688-698.
https://doi.org/10.1002/jemt.20962
Jahn, K., Olsen, E. M., Nielsen, M. M., Tørring, T., Mohammadzadegan, R., Andersen, E. S., Gothelf, K. V. & Kjems, J. (2011).
Site-Specific Chemical Labeling of Long RNA Molecules.
Bioconjugate Chemistry,
22(1), 95-100.
https://doi.org/10.1021/bc100422k
Chen, M., Hein, S., Le, D. Q. S., Nygaard, J. V., Bünger, C. & Kjems, J. (2011).
TISSUE SCAFFOLD WITH CONTROLLED DRUG RELEASE. (Patent No.
PCT/DK2011/050381).
Schaefer, A., Im, H.-I.
, Venø, M. T., Fowler, C. D., Min, A., Intrator, A.
, Kjems, J., Kenny, P. J., O'Carroll, D. & Greengard, P. (2010).
Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.
Journal of Experimental Medicine,
207(9), 1843-51.
https://doi.org/10.1084/jem.20100451Bramsen, J. B., Pakula, M. M., Hansen, T. B., Bus, C., Langkjær, N., Odadzic, D., Smicius, R., Wengel, S. L., Chattopadhyaya, J., Engels, J. W., Herdewijn, P., Wengel, J.
& Kjems, J. (2010).
A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects.
Nucleic Acids Research,
38(17), 5761-5773.
https://doi.org/10.1093/nar/gkq341
Rahbek, U. L., Nielsen, A. F., Dong, M., You, Y., Chauchereau, A., Oupicky, D.
, Besenbacher, F., Kjems, J. & Howard, K. A. (2010).
Bioresponsive hyperbranched polymers for siRNA and miRNA delivery.
Journal of Drug Targeting,
18(10), 812-20.
https://doi.org/10.3109/1061186X.2010.527982
Mittnacht, U., Hartmann, H.
, Hein, S., Oliveira, H.
, Dong, M., Pêgo, A. P.
, Kjems, J., Howard, K. A. & Schlosshauer, B. (2010).
Chitosan/siRNA nanoparticles biofunctionalize nerve implants and enable neurite outgrowth.
Nano Letters,
10(10), 3933-9.
https://doi.org/10.1021/nl1016909Mapendano, C. K., Lykke-Andersen, S., Kjems, J., Bertrand, E.
& Jensen, T. H. (2010).
Crosstalk between mRNA 3’ end processing and transcription initiation.
Molecular Cell,
40, 410-422.
Pedersen, M. B., Zhou, X., Larsen, E. K. U., Sørensen, U. S., Kjems, J., Nygaard, J. V., Nyengaard, J. R., Meyer, R. L., Boesen, T. & Vorup-Jensen, T. (2010).
Curvature of Synthetic and Natural Surfaces is an Important Target Feature in Classical Pathway Complement Activation.
Journal of Immunology,
184(4), 1931-1945.
https://doi.org/10.4049/jimmunol.0902214
Mollenhauer, J., Stamou, D.
, Flyvbjerg, A., Wengel, J., Gether, U.
, Kjems, J., Bjørnholm, T.
& Besenbacher, F. (2010).
David versus Goliath.
Nanomedicine: Nanotechnology, Biology and Medicine,
6(4), 504-9.
https://doi.org/10.1016/j.nano.2010.04.002Montanini, L., Pazzaglia, L., Spessotto, P.
, Kjems, J., Conti, A., Perris, R., den Boer, M. L. & Benassi, M. S. (2010).
Differential approach to define microRNA expression patterns in osteosarcomas.
Proceedings of the American Association of Cancer Research,
51.
Jepsen, M. DE., Nechyponuk-Zloy, V., Beerens, N., Besenbacher, F., Kjems, J. & Birkedal, V. (2010).
FRET-studies of the HIV-1 genome upon tRNA annealing.
Krüger, A. C., Raarup, M. K., Nielsen, M. M., Kristensen, M., Besenbacher, F., Kjems, J. & Birkedal, V. (2010).
Interaction of hnRNP A1 with telomere DNA G-quadruplex structures studied at the single molecule level.
European Biophysics Journal,
39(9), 1343-1350.
https://doi.org/10.1007/s00249-010-0587-x
Nawroth, I., Alsner, J., Behlke, M. A.
, Besenbacher, F., Overgaard, J., Howard, K. A. & Kjems, J. (2010).
Intraperitoneal administration of chitosan/DsiRNA nanoparticles targeting TNFα prevents radiation-induced fibrosis.
Radiotherapy & Oncology,
97(1), 143-8.
https://doi.org/10.1016/j.radonc.2010.09.010
Ostenfeld, M. S., Bramsen, J. B., Lamy, P., Villadsen, S. B., Fristrup, N., Dalsgaard Sørensen, K., Ulhøi, B. P., Borre, M., Kjems, J., Andersen, L. D. & Ørntoft, T. F. (2010).
miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors.
Oncogene,
29(7), 1073.
https://doi.org/10.1038/onc.2009.395
Nielsen, E. J. B., Nielsen, J. M., Becker, D., Karlas, A., Prakash, H.
, Glud, S. Z., Merrison, J., Besenbacher, F., Meyer, T. F.
, Kjems, J. & Howard, K. A. (2010).
Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles.
Pharmaceutical Research,
27(12), 2520-7.
https://doi.org/10.1007/s11095-010-0255-y
Madsen, J. B., Dupont, D. M., Andersen, T. B., Nielsen, A. F., Sang, L., Brix, D. M., Jensen, J. K., Broos, T., Hendrickx, M. L. V.
, Christensen, A., Kjems, J. & Andreasen, P. A. (2010).
RNA aptamers as conformational probes and regulatory agents for plasminogen activator inhibitor-1.
Biochemistry,
49(19), 4103-15.
https://doi.org/10.1021/bi100066j
Dupont, D. M., Madsen, J. B., Hartmann, R. K., Tavitian, B., Ducongé, F.
, Kjems, J. & Andreasen, P. A. (2010).
Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding.
RNA,
16(12), 2360-9.
https://doi.org/10.1261/rna.2338210
Helmig, S. W., Rotaru, A., Arian, D., Kovbasyuk, L.
, Arnbjerg, J., Ogilby, P. R., Kjems, J., Mokhir, A.
, Besenbacher, F. & Gothelf, K. V. (2010).
Single Molecule Atomic Force Microscopy Studies of Photosensitized Singlet Oxygen Behavior on a DNA Origami Template.
A C S Nano,
4(12), 7475-7480.
https://doi.org/10.1021/nn102701f
Voigt, N. V., Tørring, T., Rotaru, A., Jacobsen, M. F., Ravnsbæk, J. B., Subramani, R., Mamdouh, W., Kjems, J., Mokhir, A.
, Besenbacher, F. & Gothelf, K. V. (2010).
Single-molecule chemical reactions on DNA origami.
Nature Nanotechnology,
5(3), 200-203.
https://doi.org/10.1038/nnano.2010.5
Andersen, M. Ø., Nygaard, J. V., Burns, J. S.
, Raarup, M. K., Nyengaard, J. R., Bünger, C., Besenbacher, F., Howard, K. A., Kassem, M. & Kjems, J. (2010).
siRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells.
Molecular Therapy,
18(11), 2018-2027.
https://doi.org/10.1038/mt.2010.166
Xu, W., Wang, J.-G.
, Jacobsen, M. F., Mura, M.
, Yu, M., Kelly, R. E. A., Meng, Q.-Q.
, Lægsgaard, E., Stensgaard, I., Linderoth, T. R., Kjems, J., Kantorovich, L. N.
, Gothelf, K. V. & Besenbacher, F. (2010).
Supramolecular porous network formed by molecular recognition between chemically modified nucleobases guanine and cytosine.
Angewandte Chemie International Edition,
49(49), 9373-7.
https://doi.org/10.1002/anie.201003390
Andersen, M. Ø., Lichawska, A.
, Arpanaei, A., Jensen, S. M. R., Kaur, H., Oupicky, D.
, Besenbacher, F., Kingshott, P., Kjems, J. & Howard, K. A. (2010).
Surface functionalisation of PLGA nanoparticles for gene silencing.
Biomaterials,
31(21), 5671-5677.
https://doi.org/10.1016/j.biomaterials.2010.03.069
Kjems, J., Overgaard, J., Howard, K., Alsner, J., Besenbacher, F. & Nawroth, I. (2010).
Treatment of radiation-induced fibrosis. (Patent No.
WO2010085959A1).
Laursen, M. B., Pakula, M. M., Gao, S., Fluiter, K., Mook, O. R., Baas, F., Langklaer, N., Wengel, S. L., Wengel, J.
, Kjems, J. & Bramsen, J. B. (2010).
Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo.
Molecular BioSystems,
6(5), 862-70.
https://doi.org/10.1039/b918869j
Bramsen, J. B., Laursen, M. B., Nielsen, A. F., Hansen, T. B., Bus, C., Langkjær, N., Babu, B. R., Højland, T., Abramov, M., Van Aerschot, A., Odadzic, D., Smicius, R., Haas, J., Andree, C., Barman, J., Wenska, M., Srivastava, P., Zhou, C., Honcharenko, D.
... Kjems, J. (2009).
A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity.
Nucleic Acids Research,
37(9), 2867-81.
https://doi.org/10.1093/nar/gkp106
Wittenborn, T., Nygaard, J. V., Horsman, M. R., Vorup-Jensen, T., Kjems, J., Thim, T., Nielsen, T., Larsen, E. K. U. & Falk, E. (2009).
A Novel in Vivo Angiogenesis Mouse Model.
Arteriosclerosis, Thrombosis, and Vascular Biology, (7).
Hartmann, H., Lakner, U.
, Andersen, M. Ø., Kjems, J., Howard, K. A. & Schloßhauer, B. (2009).
Carrier Matrix for siRNA-Mediated Gene Knock Down to Promote Neuronal Regeneration. Tissue Engineering. Part A. Tissue Engineering, (3), 718.
Mistry, A.
, Glud, S. Z., Kjems, J., Nyengaard, J. R., Howard, K. A., Stolnik, S. & Illum, L. (2009).
Effect of physicochemical properties on intranasal nanoparticle transit into murine olfactory epithelium.
Journal of Drug Evaluation,
17(7), 543-552.
https://doi.org/10.1080/10611860903055470Molle, D., Segura-Morales, C., Camus, G., Berlloz-Forrent, C.
, Kjems, J., Basyuk, E. & Bertrand, E. (2009).
Endosomal Trafficking of HIV-1 Gag and Genomic RNAs Regulates Viral Egress.
Journal of Biological Chemistry,
284(29), 19727-19743.
https://doi.org/10.1074/jbc.M109.019844
