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Interdisciplinary Nanoscience Center

CellPAT

Jørgen Kjems

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Hartmann, H., Lakner, U., Andersen, M. Ø., Kjems, J., Howard, K. A. & Schloßhauer, B. (2009). Carrier Matrix for siRNA-Mediated Gene Knock Down to Promote Neuronal Regeneration. Tissue Engineering. Part A. Tissue Engineering, (3), 718.

Mistry, A., Glud, S. Z., Kjems, J., Nyengaard, J. R., Howard, K. A., Stolnik, S. & Illum, L. (2009). Effect of physicochemical properties on intranasal nanoparticle transit into murine olfactory epithelium. Journal of Drug Evaluation, 17(7), 543-552. https://doi.org/10.1080/10611860903055470

Molle, D., Segura-Morales, C., Camus, G., Berlloz-Forrent, C., Kjems, J., Basyuk, E. & Bertrand, E. (2009). Endosomal Trafficking of HIV-1 Gag and Genomic RNAs Regulates Viral Egress. Journal of Biological Chemistry, 284(29), 19727-19743. https://doi.org/10.1074/jbc.M109.019844

Kristensen, T., Christensen, M. S., Jensen, T. H., Kjems, J., Gylling, A. & Scheving, M. (2009). Experimental Molecular Biology: Laboratory Course Manual.

Andersen, L. D., Ostenfeld, M. S., Bramsen, J. B., Silahtaroglu, A., Lamy, P., Ramanathan, R., Fristrup, N., Jensen, J. L., Andersen, C. L., Zieger, K., Kauppinen, S., Ulhøi, B. P., Kjems, J., Borre, M. & Ørntoft, T. F. (2009). Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro. Cancer Research, 69(11), 4851-60. https://doi.org/10.1158/0008-5472.CAN-08-4043

Andersen, M. G. & Kjems, J. (2009). Guld får medicinen frem i kroppen. Aktuellt i Politiken.

Krüger, A. C., Nielsen, M. M., Lützelberger, M., Raarup, M. K., Kristensen, M., Kjems, J., Besenbacher, F. & Birkedal, V. (2009). Interactions between the human telomeric G-quadruplex and hnRNP A1 studied by single-molecule FRET. Poster session presented at X Annual Linz Winter Workshop, Linz, Austria.

Birkedal, V., Krüger, A. C., Nochyporuk-Zloy, V., Kjems, J. & Besenbacher, F. (2009). Methods for single molecule FRET microsocpy data analysis. Poster session presented at 15^th Anniversary International Workshop on "Single Molecule Spectroscopy and Ultra Sensitive Analysis in the Life Sciences", Berlin, Germany.

Ostenfeld, M. S., Bramsen, J. B., Lamy, P., Villadsen, S. B., Fristrup, N., Ulhøi, B. P., Borre, M., Kjems, J., Dyrskjøt, L. & Ørntoft, T. F. (2009). miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors. Oncogene. https://doi.org/10.1038/onc.2009.395

Glud, S. Z., Bramsen, J. B., Dagnaes-Hansen, F., Wengel, J., Howard, K. A., Nyengaard, J. R. & Kjems, J. (2009). Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration. Oligonucleotides, 19(2), 163-8. https://doi.org/10.1089/oli.2008.0175

Kjems, J., Howard, K. A., Besenbacher, F. & Deleuran, B. (2009). Nanoparticle-mediated treatment for inflammatory. (Patent No. WO/2009/012786). http://patentscope.wipo.int/search/en/WO2009012786

Nygaard, J. V., Andersen, M. Ø., Cloetens, P., Foss, M., Kassem, M., Kjems, J. & Besenbacher, F. (2009). Polycaprolactone nanomesh cultured with hMSC evaluated by synchrotron tomography. Poster session presented at Self-assembly: from nature to clinics, Porto, Portugal.

Andersen, M. Ø., Howard, K. A. & Kjems, J. (2009). RNAi using a chitosan/siRNA nanoparticle system: in vitro and in vivo applications. In Methods in Molecular Biology (Vol. 555, pp. 77-86) https://doi.org/10.1007/978-1-60327-295-7_6

Andersen, E. S., Dong, M., Nielsen, M. M., Jahn, K., Subramani, R., Mamdouh, W., Golas, M. M., Sander, B., Stark, H., Oliveira, C. L. P., Pedersen, J. S., Birkedal, V., Besenbacher, F., Gothelf, K. V. & Kjems, J. (2009). Self-assembly of a nanoscale DNA box with a controllable lid. Nature, 459(7243), 73-6. https://doi.org/10.1038/nature07971

Jahn, K., Nielsen, M. M., Olsen, E. M., Mohammadzadegan, R., Andersen, E. S., Gothelf, K. V. & Kjems, J. (2009). Site-specific labeling of long HIV-1 RNA using DNA templated chemistry. 84-88. Paper presented at 6th Annual Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2009, Snowbird, UT, United States.

Larsen, E. K. U., Nielsen, T., Wittenborn, T., Birkedal, H., Vorup-Jensen, T., Jakobsen, M. H., Østergaard, L., Horsman, M. R., Besenbacher, F., Howard, K. A. & Kjems, J. (2009). Size-Dependent Accumulation of PEGylated Silane-Coated Magnetic Iron Oxide Nanoparticles in Murine Tumors. A C S Nano, 3(7), 1947-51. https://doi.org/10.1021/nn900330m

Pallesen, J., Dong, M., Besenbacher, F. & Kjems, J. (2009). Structure of the HIV-1 Rev response element alone and in complex with regulator of virion (Rev) studied by atomic force microscopy. FEBS journal, 276(15), 4223-32. https://doi.org/10.1111/j.1742-4658.2009.07130.x

Gao, S., Dagnæs-Hansen, F., Nielsen, E. J. B., Wengel, J., Besenbacher, F., Howard, K. A. & Kjems, J. (2009). The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice. Molecular Therapy, 17(7), 1225-1233. https://doi.org/10.1038/mt.2009.91

Damgaard, C. K., Kahns, S., Lykke-Andersen, S., Nielsen, A. L., Jensen, T. H. & Kjems, J. (2008). A 5' splice site enhances the recruitment of basal transcription initiation factors in vivo. Molecular Cell, 29(2), 271-278. https://doi.org/10.1016/j.molcel.2007.11.035, https://doi.org/10.1016/j.molcel.2007.11.035

Dupont, D. M., Kjems, J., Andreasen, P. & Madsen, J. C. B. (2008). A new way of targeting protease-receptor binding: Selection of uPA binding RNA aptamers inhibiting its association to its receptor uPAR. Acta Pathologica Microbiologica et Immunologica Scandinavica, 443-443.

Hein, S., Wang, K., Stevens, W. & Kjems, J. (2008). Chitosan composites forbiomedical applications: status, challenges and perspectives. Materials Science and Technology, 24, 1053-1061. https://doi.org/10.1179/174328408X341744

Howard, K. A., Paludan, S. R., Behlke, M. A., Besenbacher, F., Deleuran, B. W. & Kjems, J. (2008). Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model. Molecular Therapy, 17(1), 162-168. https://doi.org/10.1038/mt.2008.220

Torarinsson, E., Yao, Z., Wiklund, E. D., Bramsen, J. B., Hansen, C. A., Kjems, J., Tommerup, N., Ruzzo, W. L. & Gorodkin, J. (2008). Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions. Genome Research, 18(2), 242-251. https://doi.org/10.1101/gr.6887408

Andersen, M. Ø., Howard, K. A., Paludan, S. R., Besenbacher, F. & Kjems, J. (2008). Delivery of siRNA from lyophilized polymeric surfaces. Biomaterials, 29(4), 506-512. https://doi.org/10.1016/j.biomaterials.2007.10.003

Andersen, E. S., Dong, M., Nielsen, M. M., Jahn, K., Lind-Thomsen, A., Mamdouh, W., Gothelf, K. V., Besenbacher, F. & Kjems, J. (2008). DNA origami design of dolphin-shaped structures with flexible tails. A C S Nano, 2(6), 1213-8. https://doi.org/10.1021/nn800215j

Rahbek, U. L., Howard, K. A., Oupicky, D., Manickam, D. S., Dong, M., Nielsen, A. F., Hansen, T. B., Besenbacher, F. & Kjems, J. (2008). Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides. Journal of Gene Medicine, 10(1), 81-93. https://doi.org/10.1002/jgm.1120

Nygaard, J. V., Andersen, M. Ø., Howard, K. A., Foss, M., Bünger, C., Kjems, J. & Besenbacher, F. (2008). Investigation of particle-functionalized tissue engineering scaffolds using X-ray tomographic microscopy. Biotechnology and Bioengineering (Print), 100(4), 820-9. https://doi.org/10.1002/bit.21796

Nygaard, J. V., Andersen, M. Ø., Cloetens, P., Foss, M., Kassem, M., Kjems, J. & Besenbacher, F. (2008). Nanoscaffolds for Drug Delivery and Tissue Engineering. Poster session presented at iNANO 6^th annual meeting, Aarhus, Denmark.

Astakhova, I., Korshun, V. A., Jahn, K., Kjems, J. & Wengel, J. (2008). Perylene attached to 2'-amino-LNA: synthesis, incorporation into oligonucleotides, and remarkable fluorescence properties in vitro and in cell culture. Bioconjugate Chemistry, 19(10), 1995-2007. https://doi.org/10.1021/bc800202v

Skivesen, N., Tetu, A., Kristensen, M., Kjems, J., Frandsen, L. H. & Borel, P. I. (2008). Protein detection with a planar photonic-crystal sensor. Paper presented at CLEO-EU, Munich, Germany.

Bramsen, J. B., Kjems, J., Ørntoft, T. F., Andersen, L. D. & Ostenfeld, M. S. (2008). Reintroduction of bladder cancer-downregulated miR-145 results in massive cell death of bladder cancer cell lines. Acta Pathologica Microbiologica et Immunologica Scandinavica, 417-417. https://doi.org/10.1111/j.1600-0463.2008.001165_13.x

Andersen, E. S., Nielsen, M. M., Dong, M., Besenbacher, F., Kjems, J. & Gothelf, K. V. (2008). Software package for the design and analysis of DNA origami structures. Paper presented at FNANO 2008, Snowbird, United States.

Otero Martin, R., Xu, W., Lukas, M., Kelly, R. E. A., Laegsgaard, E., Stensgaard, I., Kjems, J., Kantorovich, L. N. & Besenbacher, F. (2008). Specificity of Watson-Crick Base Pairing on a Solid Surface Studied at the Atomic Scale. Angewandte Chemie, 47(50), 9673-9676. https://doi.org/10.1002/anie.200803333

Odadzic, D., Bramsen, J. B., Smicius, R., Bus, C., Kjems, J. & Engels, J. W. (2008). Synthesis of 2'-O-modified adenosine building blocks and application for RNA interference. Bioorganic & Medicinal Chemistry, 16(1), 518-529. https://doi.org/10.1016/j.bmc.2007.09.019

Lykke-Andersen, S., Piñol-Roma, S. & Kjems, J. (2007). Alternative splicing of the ADAR1 transcript in a region that functions either as a 5'-UTR or an ORF. RNA, 13(10), 1732-1744. https://doi.org/10.1261/rna.567807

Dupont, D. M., Madsen, J. B., Kjems, J. & Andreasen, P. (2007). A novel type of agent blocking the association of uPA to its receptor uPAR: uPA-binding aptamers. Abstract from XIth International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Stockholm, Sweden.

Dauksaite, V., Lorentzenn, M., Besenbacher, F. & Kjems, J. (2007). Antibody-based protein detection using piezoresistive cantilever array. Nanotechnology, 18, 1-5.

Liu, X., Howard, K. A., Dong, M. & Kjems, J. (2007). Chitosan/siRNA nanoparticles for gene silencing: formulation and characterization. Biomaterials, 28, 1280-1288.

Xu, S., Dong, M., Liu, X., Howard, K. A., Kjems, J. & Besenbacher, F. (2007). Direct force measurements between siRNA and chitosan molecules using force spectroscopy. Biophysical Journal, 93(3), 952-9. https://doi.org/10.1529/biophysj.106.093229

Jakobsen, M. R., Haasnoot, J., Wengel, J., Berkhout, B. & Kjems, J. (2007). Efficient inhibition of HIV-1 expression by LNA modified antisense oligonucleotides and DNAzymes targeted to functionally selected binding sites. Retrovirology, 4(29), 1-13. https://doi.org/10.1186/1742-4690-4-29

Bramsen, J. B., Laursen, M. B., Damgaard, C. K., Lena, S. W., Babu, B. R., Wengel, J. & Kjems, J. (2007). Improved silencing properties using small internally segmented interfering RNAs. Nucleic Acids Research, 35(17), 5886-5897. https://doi.org/10.1093/nar/gkm548

Bak, R. O., Andersen, M. Ø., Howard, K. A. & Kjems, J. (2007). Localized Delivery of Lyophilized siRNA polyplexes. Poster session presented at INASCON, Aarhus, Denmark.

Skivesen, N., Kristensen, M., Kjems, J., Frandsen, L. H., Borel, P. I. & Tetu, A. (2007). Metal-clad waveguides anvendt som optiske bio-sensorer. D O P S - Nyt, 07(1), 20.

Howard, K. A., Dong, M., Oupicky, D., Bisht, H. S., Buss, C., Besenbacher, F. & Kjems, J. (2007). Nanocarrier stimuli-activated gene delivery. Small, 3(1), 54-7. https://doi.org/10.1002/smll.200600328

Skivesen, N., Têtu, A., Kristensen, M., Kjems, J., Frandsen, L. H. & Borel, P. I. (2007). Photonic-crystal waveguide biosensor. Optics Express, 15(6), 3169-3176.

Skivesen, N., Tetu, A., Kristensen, M., Kjems, J., Frandsen, L. H. & Borel, P. I. (2007). Planar photonic crystal waveguide biosensor. Poster session presented at ECIO, København, Denmark.

Howard, K. A. & Kjems, J. (2007). Polycation-based nanoparticle delivery for improved RNA interference therapeutics. Expert opinion on biological therapy, 7(12), 1811-1822. https://doi.org/10.1517/14712598.7.12.1811

Howard, K. A. & Kjems, J. (2007). Polycation-based nanoparticle delivery for improved RNAi therapeutics. Expert Opin. Biol. Ther, 7, 1811-1822.

Nielsen, K. B., Sørensen, S., Cartegni, L., Corydon, T. J., Doktor, T. K., Schroeder, L. D., Reinert, L. S., Elpeleg, O., Krainer, A. R., Gregersen, N., Kjems, J. & Andresen, B. S. (2007). Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations: a synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a flanking exonic splicing enhancer. American Journal of Human Genetics, 80(3), 416-432. https://doi.org/10.1086/511992

Andersen, E. S., Lind-Thomsen, A., Knudsen, B., Kristensen, S. E., Havgaard, J. H., Torarinsson, E., Larsen, N., Zwieb, C., Sestoft, P., Kjems, J. & Gorodkin, J. (2007). Semiautomated improvement of RNA alignments. RNA, 13, 1850-1859.

Displaying results 301 to 350 out of 419

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Revised 17.04.2023

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Anne Færch Nielsen