Kirkegaard, K., Yan, Y., Sørensen, B. S., Hardason, T., Hanson, C., Ingerslev, H. J.
, Knudsen, U. B., Kjems, J., Lundin, K. & Ahlström, A. (2020).
Comprehensive analysis of soluble RNAs in human embryo culture media and blastocoel fluid.
Journal of Assisted Reproduction and Genetics,
37(9), 2199–2209.
https://doi.org/10.1007/s10815-020-01891-7
Omer, M., Andersen, V. L., Nielsen, J. S., Wengel, J.
& Kjems, J. (2020).
Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds.
Molecular Therapy - Nucleic Acids,
22, 994-1003.
https://doi.org/10.1016/j.omtn.2020.10.013
Mortensen, M. R., Skovsgaard, M. B., Märcher, A., Andersen, V. L., Palmfeldt, J., Nielsen, T. B., Tørring, T., Laursen, N. S., Andersen, K. R., Kjems, J. & Gothelf, K. V. (2020).
Introduction of an Aldehyde Handle on Nanobodies by Affinity-Guided Labeling.
Bioconjugate Chemistry,
31(5), 1295-1300.
https://doi.org/10.1021/acs.bioconjchem.0c00151
Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N.
, Kjems, J. ... LifeTime Community Working Groups (2020).
LifeTime and improving European healthcare through cell-based interceptive medicine.
Nature,
587, 377-386.
https://doi.org/10.1038/s41586-020-2715-9Gonçalves, N. P., Yan, Y., Ulrichsen, M., Venø, M. T., Poulsen, E. T., Enghild, J. J., Kjems, J. & Vægter, C. B. (2020).
Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin.
Biomedicines,
8(11), 1-24. Article 450.
https://doi.org/10.3390/biomedicines8110450
Yan, Y., Chang, C., Su, J., Venø, M. T. & Kjems, J. (2020).
Osteoblastogenesis Alters Small RNA Profiles in EVs Derived from Bone Marrow Stem Cells (BMSCs) and Adipose Stem Cells (ASCs).
Biomedicines,
8(10), 1-17. Article 387.
https://doi.org/10.3390/biomedicines8100387
Godskesen, L. E.
, Lassen, T. R., Jespersen, N. R., Siersbæk, M.
, Yan, Y., Nielsen, M. M., Tjønnfjord, S. K., Grøntved, L., Madsen, G.
, Kjems, J., Bøtker, H. E., Schmidt, M. R., Krag, A. & Kjeldsen, J. (2020).
Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial.
Scientific Reports,
10(1), Article 9537.
https://doi.org/10.1038/s41598-020-65692-9Kristensen, L. S., Ebbesen, K. K., Sokol, M., Jakobsen, T., Korsgaard, U., Eriksen, A. C.
, Hansen, T. B., Kjems, J. & Hager, H. (2020).
Spatial expression analyses of the putative oncogene ciRS-7 in cancer reshape the microRNA sponge theory.
Nature Communications,
11, Article 4551.
https://doi.org/10.1038/s41467-020-18355-2
Thomsen, R. P., Malle, M. G.
, Okholm, A. H., Krishnan, S., Bohr, S. S. R.
, Sørensen, R. S., Ries, O., Vogel, S., Simmel, F. C., Hatzakis, N. S.
& Kjems, J. (2019).
A large size-selective DNA nanopore with sensing applications.
Nature Communications,
10(1), Article 5655.
https://doi.org/10.1038/s41467-019-13284-1
Høiberg, H. C., Sparvath, S. M., Andersen, V. L., Kjems, J. & Andersen, E. S. (2019).
An RNA origami octahedron with intrinsic siRNAs for potent gene knockdown.
Biotechnology Journal,
14(1), Article 1700634.
https://doi.org/10.1002/biot.201700634
Andersen, V. L., Vinther, M., Kumar, R., Ries, A., Wengel, J.
, Nielsen, J. S. & Kjems, J. (2019).
A self-assembled, modular nucleic acid-based nanoscaffold for multivalent theranostic medicine.
Theranostics,
9(9), 2662-2677.
https://doi.org/10.7150/thno.32060
Raniolo, S., Croce, S.
, Thomsen, R. P., Okholm, A. H., Unida, V., Iacovelli, F., Manetto, A.
, Kjems, J., Desideri, A. & Biocca, S. (2019).
Cellular uptake of covalent and non-covalent DNA nanostructures with different sizes and geometries.
Nanoscale,
11(22), 10808-10818.
https://doi.org/10.1039/c9nr02006cMeyer, R. L., Walther, R., Nielsen, S. M., Andersen, P. O., Hansen, L., Vu-Quang, H., Kjems, J. & Zelikin, A. N. (2019).
Delivering antibiotics locally to biofilms by targeted drug delivery and prodrug therapy. Abstract from Eurobiofilms 2019, Glasgow, United Kingdom.
Costard, L. S., Neubert, V.
, Venø, M. T., Su, J., Kjems, J., Connolly, N. M. C., Prehn, J. H. M., Schratt, G., Henshall, D. C., Rosenow, F. & Bauer, S. (2019).
Electrical stimulation of the ventral hippocampal commissure delays experimental epilepsy and is associated with altered microRNA expression.
Brain Stimulation,
12(6), 1390-1401.
https://doi.org/10.1016/j.brs.2019.06.009Klein, W. P.
, Thomsen, R. P., Turner, K. B., Walper, S. A., Vranish, J.
, Kjems, J., Ancona, M. G. & Medintz, I. L. (2019).
Enhanced Catalysis from Multienzyme Cascades Assembled on a DNA Origami Triangle.
ACS Nano,
13(12), 13677-13689.
https://doi.org/10.1021/acsnano.9b05746Krissanaprasit, A., Key, C., Fergione, M., Froehlich, K., Pontula, S., Hart, M., Carriel, P.
, Kjems, J., Andersen, E. S. & LaBean, T. H. (2019).
Genetically Encoded, Functional Single-Strand RNA Origami: Anticoagulant.
Advanced Materials,
31(21), Article 1808262.
https://doi.org/10.1002/adma.201808262
Moldovan, L.-I., Hansen, T. B., Venø, M. T., Okholm, T. L. H., Andersen, T. L., Hager, H.
, Iversen, L., Kjems, J., Johansen, C. & Kristensen, L. S. (2019).
High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome.
BMC Medical Genomics,
12(1), Article 174.
https://doi.org/10.1186/s12920-019-0616-2
Vu-Quang, H., Vinding, M. S., Jakobsen, M., Song, P., Dagnaes-Hansen, F., Nielsen, N. C. & Kjems, J. (2019).
Imaging rheumatoid arthritis in mice using combined near infrared and 19F magnetic resonance modalities.
Scientific Reports,
9, Article 14314.
https://doi.org/10.1038/s41598-019-50043-0
Yan, Y., Chang, C. C., Venø, M. T., Mothershead, C. R., Su, J. & Kjems, J. (2019).
Isolating, Sequencing and Analyzing Extracellular MicroRNAs from Human Mesenchymal Stem Cells.
Journal of visualized experiments : JoVE,
2019(145), Article e58655.
https://doi.org/10.3791/58655
Song, P., Yang, C., Thomsen, J. S., Dagnaes-Hansen, F., Jakobsen, M., Bruel, A., Deleuran, B. & Kjems, J. (2019).
Lipidoid-siRNA Nanoparticle-Mediated IL-1 beta Gene Silencing for Systemic Arthritis Therapy in a Mouse Model.
Molecular Therapy,
27(8), 1424-1435.
https://doi.org/10.1016/j.ymthe.2019.05.002
Nielsen, T. B., Thomsen, R. P., Mortensen, M. R., Kjems, J., Nielsen, P. F., Nielsen, T. E.
, Kodal, A. L. B., Cló, E.
& Gothelf, K. V. (2019).
Peptide-Directed DNA-Templated Protein Labelling for The Assembly of a Pseudo-IgM.
Angewandte Chemie International Edition,
58(27), 9068-9072.
https://doi.org/10.1002/anie.201903134
Vu-Quang, H., Vinding, M. S., Nielsen, T., Ullisch, M. G., Nielsen, N. C., Nguyen, D. T.
& Kjems, J. (2019).
Pluronic F127-folate coated super paramagenic iron oxide nanoparticles as contrast agent for cancer diagnosis in magnetic resonance imaging.
Polymers,
11(4), Article 743.
https://doi.org/10.3390/polym11040743
Liu, T., Song, P., Märcher, A., Kjems, J., Yang, C. & Gothelf, K. V. (2019).
Selective delivery of doxorubicin to EGFR+ cancer cells by Cetuximab‐DNA conjugates.
ChemBioChem,
20(8), 1014-1018.
https://doi.org/10.1002/cbic.201800685
Jepsen, M. D. E., Sørensen, R. S., Maffeo, C., Aksimentiev, A.
, Kjems, J. & Birkedal, V. (2019).
Single molecule analysis of structural fluctuations in DNA nanostructures.
Nanoscale,
11(39), 18475-18482.
https://doi.org/10.1039/c9nr03826d
Verboom, K., Everaert, C., Bolduc, N., Livak, K. J., Yigit, N., Rombaut, D., Anckaert, J., Lee, S.
, Venø, M. T., Kjems, J., Speleman, F., Mestdagh, P. & Vandesompele, J. (2019).
SMARTer single cell total RNA sequencing.
Nucleic Acids Research,
47(16), Article e93.
https://doi.org/10.1093/nar/gkz535Prabha, R. D., Nair, B. P., Ditzel, N.
, Kjems, J., Nair, P. D. & Kassem, M. (2019).
Strontium functionalized scaffold for bone tissue engineering.
Materials Science and Engineering C,
94, 509-515.
https://doi.org/10.1016/j.msec.2018.09.054
Kristensen, L. S., Schertz Andersen, M., Stagsted, L. V. W., Ebbesen, K., Hansen, T. B. & Kjems, J. (2019).
The biogenesis, biology and characterization of circular RNAs.
Nature Reviews. Genetics,
20(11), 675-691.
https://doi.org/10.1038/s41576-019-0158-7
Knudsen, C. H., ásgrímsdóttir, E. S., Rahimi, K., Gill, K. P., Frandsen, S., Buchholdt, S. H., Chen, M., Kjems, J., Febbraro, F. & Denham, M. (2018).
A modified monomeric red fluorescent protein reporter for assessing CRISPR activity.
Frontiers in Cell and Developmental Biology,
6(MAY), Article 54.
https://doi.org/10.3389/fcell.2018.00054
Nielsen, C. K., Subbiahdoss, G., Zeng, G., Salmi, Z., Kjems, J., Mygind, T., Snabe, T.
& Meyer, R. L. (2018).
Antibacterial isoeugenol coating on stainless steel and polyethylene surfaces prevents biofilm growth.
Journal of Applied Microbiology,
124(1), 179-187.
https://doi.org/10.1111/jam.13634
Prabha, R. D., Kraft, D. C. E., Harkness, L.
, Melsen, B., Varma, H., Nair, P. D.
, Kjems, J. & Kassem, M. (2018).
Bioactive Nano-fibrous Scaffold for Vascularized Craniofacial Bone Regeneration.
Journal of Tissue Engineering and Regenerative Medicine,
12(3), e1537-e1548.
https://doi.org/10.1002/term.2579
Song, W., Yang, C., Svend Le, D. Q., Zhang, Y.
& Kjems, J. (2018).
Calcium-microRNA Complexes Functionalized Nanotubular Implant Surface for Highly Efficient Transfection and Enhanced Osteogenesis of Mesenchymal Stem Cells.
A C S Applied Materials and Interfaces,
10(9), 7756-7764.
https://doi.org/10.1021/acsami.7b18289
Vu Quang, H., Chang, C.-C., Song, P., Hauge, E. M. & Kjems, J. (2018).
Caveolae-mediated mesenchymal stem cell labelling by PSS-coated PLGA PFOB nano-contrast agent for MRI.
Theranostics,
8(10), 2657-2671.
https://doi.org/10.7150/thno.23206
Stoll, L., Sobel, J., Rodriguez-Trejo, A., Guay, C., Lee, K.
, Venø, M. T., Kjems, J., Laybutt, D. R. & Regazzi, R. (2018).
Circular RNAs as novel regulators of β-cell functions in normal and disease conditions.
Molecular Metabolism,
9, 69-83.
https://doi.org/10.1016/j.molmet.2018.01.010Domaljanovic, I., Rexen Ulven, E., Ulven, T.
, Thomsen, R. P., Okholm, A. H., Kjems, J., Voss, A., Taskova, M. & Astakhova, K. (2018).
Dihydropyridine fluorophores allow for specific detection of human antibodies in serum.
ACS Omega,
3(7), 7580–7586.
https://doi.org/10.1021/acsomega.8b00424Hollensen, A. K., Andersen, S., Hjorth, K., Bak, R. O., Hansen, T. B., Kjems, J., Aagaard, L., Damgaard, C. K. & Mikkelsen, J. G. (2018).
Enhanced Tailored MicroRNA Sponge Activity of RNA Pol II-Transcribed TuD Hairpins Relative to Ectopically Expressed ciRS7-Derived circRNAs.
Molecular Therapy - Nucleic Acids,
13, 365-375.
https://doi.org/10.1016/j.omtn.2018.09.009
Dahl, M.
, Daugaard, I., Andersen, M. S., Hansen, T. B., Grønbæk, K., Kjems, J. & Kristensen, L. S. (2018).
Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies.
Laboratory Investigation,
98(12), 1657–1669.
https://doi.org/10.1038/s41374-018-0108-6Chang, C. C., Venø, M. T., Chen, L., Ditzel, N.
, Le, D. Q. S., Dillschneider, P., Kassem, M.
& Kjems, J. (2018).
Global MicroRNA Profiling in Human Bone Marrow Skeletal—Stromal or Mesenchymal–Stem Cells Identified Candidates for Bone Regeneration.
Molecular Therapy,
26(2), 593-605.
https://doi.org/10.1016/j.ymthe.2017.11.018
Subrizi, A., Yang, C., Ilmarinen, T., Skottman, H., Urtti, A.
& Kjems, J. (2018).
Lipidoid-siRNA formulations promote gene silencing in differentiated and nondividing ARPE-19, primary porcine and human embryonic stem cell-derived retinal pigment epithelial cells. Abstract from Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu.
https://iovs.arvojournals.org/article.aspx?articleid=2693003&resultClick=1
Pérez Quiñones, J., Brüggemann, O.
, Kjems, J., Shahavi, M. H. & Peniche Covas, C. (2018).
Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals.
Journal of Agricultural and Food Chemistry,
66(7), 1612-1619.
https://doi.org/10.1021/acs.jafc.7b05019
Mortensen, M. R., Skovsgaard, M. B., Okholm, A. H., Scavenius, C., Dupont, D. M., Rosen, C. B., Enghild, J. J., Kjems, J. & Gothelf, K. V. (2018).
Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins.
Bioconjugate Chemistry,
29(9), 3016–3025.
https://doi.org/10.1021/acs.bioconjchem.8b00424
Yang, C., Gao, S., Song, P., Dagnæs-Hansen, F., Jakobsen, M. V. & Kjems, J. (2018).
Theranostic Niosomes for Efficient siRNA/microRNA Delivery and Activatable Near-Infrared Fluorescent Tracking of Stem Cells.
A C S Applied Materials and Interfaces,
10(23), 19494–19503.
https://doi.org/10.1021/acsami.8b05513
Löffler, P. M. G., Ries, O., Rabe, A.
, Okholm, A. H., Thomsen, R. P., Kjems, J. & Vogel, S. (2017).
A DNA-programmed liposome fusion cascade.
Angewandte Chemie International Edition,
56(43), 13228–13231.
https://doi.org/10.1002/anie.201703243Rajman, M., Metge, F., Fiore, R., Khudayberdiev, S., Aksoy-Aksel, A., Bicker, S., Reschke, C. R., Raoof, R., Brennan, G. P., Delanty, N., Farrell, M. A., O'Brien, D. F., Bauer, S., Norwood, B.
, Veno, M. T., Krueger, M., Braun, T.
, Kjems, J., Rosenow, F. ... Schratt, G. (2017).
A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses.
EMBO Journal,
36(12), 1770-1787.
https://doi.org/10.15252/embj.201695748Nielsen, C. K., Kjems, J., Mygind, T., Snabe, T., Schwarz, K., Serfert, Y.
& Meyer, R. L. (2017).
Antimicrobial effect of emulsion-encapsulated isoeugenol against biofilms of food pathogens and spoilage bacteria.
International Journal of Food Microbiology,
242, 7–12.
https://doi.org/10.1016/j.ijfoodmicro.2016.11.002
