Nawroth, I.
, Alsner, J., Behlke, M. A.
, Besenbacher, F., Overgaard, J., Howard, K. A. & Kjems, J. (2010).
Intraperitoneal administration of chitosan/DsiRNA nanoparticles targeting TNFα prevents radiation-induced fibrosis.
Radiotherapy & Oncology,
97(1), 143-8.
https://doi.org/10.1016/j.radonc.2010.09.010
Rahbek, U. L.
, Howard, K. A., Oupicky, D., Manickam, D. S.
, Dong, M., Nielsen, A. F., Hansen, T. B.
, Besenbacher, F. & Kjems, J. (2008).
Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides.
Journal of Gene Medicine,
10(1), 81-93.
https://doi.org/10.1002/jgm.1120
Schaffert, D. H., Okholm, A. H., Sørensen, R. S., Nielsen, J.
, Tørring, T., Rosen, C. B., Kodal, A. L. B., Mortensen, M. R.
, Gothelf, K. V. & Kjems, J. (2016).
Intracellular Delivery of a Planar DNA Origami Structure by the Transferrin-Receptor Internalization Pathway.
Small,
12(19), 2634-2640.
https://doi.org/10.1002/smll.201503934
Krüger, A. C.
, Nielsen, M. M., Lützelberger, M., Raarup, M. K., Kristensen, M.
, Kjems, J., Besenbacher, F. & Birkedal, V. (2009).
Interactions between the human telomeric G-quadruplex and hnRNP A1 studied by single-molecule FRET. Poster session presented at X Annual Linz Winter Workshop, Linz, Austria.
Krüger, A. C., Raarup, M. K.
, Nielsen, M. M., Kristensen, M.
, Besenbacher, F., Kjems, J. & Birkedal, V. (2010).
Interaction of hnRNP A1 with telomere DNA G-quadruplex structures studied at the single molecule level.
European Biophysics Journal,
39(9), 1343-1350.
https://doi.org/10.1007/s00249-010-0587-x
Chen, M., Le, D. Q. S.
, Kjems, J., Bünger, C. & Lysdahl, H. (2015).
Improvement of distribution and osteogenic differentiation of human mesenchymal stem cells by hyaluronic acid and β-tricalcium phosphate-coated polymeric scaffold in vitro.
BioResearch Open Access,
4(1), 363-373.
https://doi.org/10.1089/biores.2015.0021
Bramsen, J. B., Laursen, M. B.
, Damgaard, C. K., Lena, S. W., Babu, B. R., Wengel, J.
& Kjems, J. (2007).
Improved silencing properties using small internally segmented interfering RNAs.
Nucleic Acids Research,
35(17), 5886-5897.
https://doi.org/10.1093/nar/gkm548
Omer, M., Andersen, V. L., Nielsen, J. S., Wengel, J.
& Kjems, J. (2020).
Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds.
Molecular Therapy - Nucleic Acids,
22, 994-1003.
https://doi.org/10.1016/j.omtn.2020.10.013
Wedge, E.
, Ahmadov, U., Hansen, T. B., Gao, Z., Tulstrup, M., Côme, C., Nonavinkere Srivatsan, S., Ahmed, T., Jespersen, J. S., Schlotmann, B. C., Schöllkopf, C., Raaschou-Jensen, K., Ødum, N.
, Kjems, J., Bak, R. O., Walter, M. J., Grønbæk, K.
& Kristensen, L. S. (2023).
Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms.
Leukemia,
37(5), 1113-1125.
https://doi.org/10.1038/s41375-023-01866-4
Yang, C., Gao, S., Dagnæs-Hansen, F., Jakobsen, M.
& Kjems, J. (2017).
Impact of PEG Chain Length on the Physical Properties and Bioactivity of PEGylated Chitosan/siRNA Nanoparticles in Vitro and in Vivo.
A C S Applied Materials and Interfaces,
9(14), 12203-12216.
https://doi.org/10.1021/acsami.6b16556
Vu-Quang, H.
, Vinding, M. S., Jakobsen, M.
, Song, P., Dagnaes-Hansen, F.
, Nielsen, N. C. & Kjems, J. (2019).
Imaging rheumatoid arthritis in mice using combined near infrared and 19F magnetic resonance modalities.
Scientific Reports,
9, Article 14314.
https://doi.org/10.1038/s41598-019-50043-0
Yu, M., Wang, J., Mura, M., Meng, Q.-Q., Xu, W., Gersen, H., Lægsgaard, E., Stensgaard, I., Kelly, R. E. A.
, Kjems, J., Linderoth, T. R., Kantorovich, L. N.
& Besenbacher, F. (2011).
Homochiral Xanthine Quintet Networks Self-Assembled on Au(111) Surfaces.
ACS Nano,
5(8), 6651-6660.
https://doi.org/10.1021/nn202157m
Furnes, C., Arnesen, T., Askjaer, P.
, Kjems, J. & Szilvay, A. M. (2005).
HIV-1 Rev oligomerization is not obligatory in the presence of an extra basic domain.
Retrovirology,
2, 39.
https://doi.org/10.1186/1742-4690-2-39
Mohey, R.
, Tolstrup, M., Jørgensen, L. B.
, Møller, B. K., Black, F. T.
, Kjems, J. & Obel, N. (2006).
HIV-1 reverse Transcriptase Gene 103K/N and 184M/V Combinations in Tandem: Detection and Quantification of HIV-1 Populations in the CD45RO+ T-cell Compartment by a Double-ARMS Real-Time PCR assay.
J A I D S,
41(2), 160-167.
https://doi.org/10.1097/01.qai.0000191998.70034.64
Moldovan, L.-I., Hansen, T. B., Venø, M. T., Okholm, T. L. H.
, Andersen, T. L., Hager, H.
, Iversen, L., Kjems, J., Johansen, C. & Kristensen, L. S. (2019).
High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome.
BMC Medical Genomics,
12(1), Article 174.
https://doi.org/10.1186/s12920-019-0616-2
Krüger, A. C.
, Nielsen, M. M., Kjems, J., Besenbacher, F. & Birkedal, V. (2011).
G-quadruplex structures in telomeric DNA studied with single molecule FRET microscopy. Poster session presented at Third International Meeting on G-Quadruplex and G-assembly, Sorrento, Italy.
http://f1000.com/posters/browse?conferenceId=297
Chang, C. C., Venø, M. T., Chen, L., Ditzel, N., Le, D. Q. S., Dillschneider, P., Kassem, M.
& Kjems, J. (2018).
Global MicroRNA Profiling in Human Bone Marrow Skeletal—Stromal or Mesenchymal–Stem Cells Identified Candidates for Bone Regeneration.
Molecular Therapy,
26(2), 593-605.
https://doi.org/10.1016/j.ymthe.2017.11.018
Seeler, S., Moldovan, L.-I.
, Bertelsen, T., Hager, H., Iversen, L., Johansen, C., Kjems, J. & Sommer Kristensen, L. (2022).
Global circRNA expression changes predate clinical and histological improvements of psoriasis patients upon secukinumab treatment.
PLOS ONE,
17(9), Article e0275219.
https://doi.org/10.1371/journal.pone.0275219
Andersen, L. D., Ostenfeld, M. S.
, Bramsen, J. B., Silahtaroglu, A.
, Lamy, P., Ramanathan, R.
, Fristrup, N., Jensen, J. L., Andersen, C. L., Zieger, K., Kauppinen, S., Ulhøi, B. P.
, Kjems, J., Borre, M. & Ørntoft, T. F. (2009).
Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro. Cancer Research,
69(11), 4851-60.
https://doi.org/10.1158/0008-5472.CAN-08-4043
Jakobsen, T., Dahl, M., Dimopoulos, K., Grønbæk, K.
, Kjems, J. & Kristensen, L. S. (2021).
Genome-wide circular RNA expression patterns reflect resistance to immunomodulatory drugs in multiple myeloma cells.
Cancers,
13(3), Article 365.
https://doi.org/10.3390/cancers13030365
Krissanaprasit, A., Key, C., Fergione, M., Froehlich, K., Pontula, S., Hart, M., Carriel, P.
, Kjems, J., Andersen, E. S. & LaBean, T. H. (2019).
Genetically Encoded, Functional Single-Strand RNA Origami: Anticoagulant.
Advanced Materials,
31(21), Article 1808262.
https://doi.org/10.1002/adma.201808262
Jensen, S. M. R.
, Schmitz, A., Pedersen, F. S., Kjems, J. & Bramsen, J. B. (2012).
Functional selection of shRNA loops from randomized retroviral libraries.
P L o S One,
7(8), e43095.
https://doi.org/10.1371/journal.pone.0043095
Jahn, K.
, Tørring, T., Voigt, N. V., Sørensen, R. S., Kodal, A. L. B.
, Andersen, E. S., Gothelf, K. V. & Kjems, J. (2011).
Functional Patterning of DNA Origami by Parallel Enzymatic Modification.
Bioconjugate Chemistry,
22(4), 819-823.
https://doi.org/10.1021/bc2000098
Märcher, A., Kumar, V., Andersen, V. L., El-Chami, K., Nguyen, T. J. D.
, Skaanning, M. K., Rudnik-Jansen, I., Nielsen, J. S.
, Howard, K. A., Kjems, J. & Gothelf, K. V. (2022).
Functionalized Acyclic (l)-Threoninol Nucleic Acid Four-Way Junction with High Stability In Vitro and In Vivo.
Angewandte Chemie - International Edition,
61(24), Article 202115275.
https://doi.org/10.1002/anie.202115275
Cunyat, F., Beerens, N., Garcia, E., Clotet, B.
, Kjems, J. & Cabrera, C. (2014).
Functional Analyses Reveal Extensive RRE Plasticity in Primary HIV-1 Sequences Selected under Selective Pressure.
P L o S One,
9(8), Article 106299.
https://doi.org/10.1371/journal.pone.0106299
Sukosd, Z.
, Andersen, E. S., Seemann, S. E., Jensen, M., Hansen, M. B., Gorodkin, J.
& Kjems, J. (2015).
Full-length RNA structure prediction of the HIV-1 genome reveals a conserved core domain.
Nucleic Acids Research,
43(21), 10168-10179.
https://doi.org/10.1093/nar/gkv1039
Jepsen, M. DE., Nechyponuk-Zloy, V., Beerens, N.
, Besenbacher, F., Kjems, J. & Birkedal, V. (2010).
FRET-studies of the HIV-1 genome upon tRNA annealing.
Chen, M., Hein, S., Le, D. Q. S., Feng, W.
, Foss, M., Kjems, J., Besenbacher, F., Zou, X. & Bünger, C. (2013).
Free radicals generated by tantalum implants antagonize the cytotoxic effect of doxorubicin.
International Journal of Pharmaceutics,
448(1), 214-20.
https://doi.org/10.1016/j.ijpharm.2013.03.041
Hvam, M. L., Cai, Y., Dagnæs-Hansen, F., Nielsen, J., Wengel, J.
, Kjems, J. & Howard, K. (2017).
Fatty acid-modified gapmer antisense oligonucleotide and human serum albumin constructs for pharmacokinetic modulation.
Molecular Therapy,
25(7), 1710-1717.
https://doi.org/10.1016/j.ymthe.2017.05.009
Chen, M., Le, D. Q. S., Hein, S., Li, P.
, Nygaard, J. V., Kassem, M.
, Kjems, J., Besenbacher, F. & Bünger, C. (2012).
Fabrication and characterization of a rapid prototyped tissue engineering scaffold with embedded multicomponent matrix for controlled drug release.
International Journal of Nanomedicine (Online), (7), 4285-97.
https://doi.org/10.2147/IJN.S33083
Song, P., Staulund, J., Qi, H.
, Thrane, L., Pedersen, M., Eijken, M., Jespersen, B. & Kjems, J. (2022).
Ex-vivo mRNA therapy to predict kidney vitality during transplantation. Poster session presented at Danish RNA Society's 7th Annual Meeting, Aarhus, Denmark.
Greisen, S. R., Yan, Y.
, Hansen, A. S., Veno, M. T.
, Nyengaard, J. R., Moestrup, S. K., Hvid, M., Freeman, G. J.
, Kjems, J. & Deleuran, B. (2017).
Extracellular Vesicles Transfer the Receptor Programmed Death-1 in Rheumatoid Arthritis.
Frontiers in Immunology,
8(JUL), Article 851.
https://doi.org/10.3389/fimmu.2017.00851
Østergaard, R. H., Yan, Y., Venø, M. T.
, Dinesen, A., Kjaer-Sorensen, K., Oxvig, C., Rasmussen, J. T., Howard, K., Kjems, J., van Niel, G., Verweij, F.
& Hayashi, Y. (2022).
Extracellular Vesicle Biology Meets Zebrafish: Real-Time Visualization and RNA Profiling of Physiological Exosomes in the Bloodstream. Poster session presented at The Danish Society for Extracellular Vesicles (DSEV) 3rd Annual Symposium 2022, Roskilde, Denmark.
Dahl, M., Husby, S., Eskelund, C. W.
, Besenbacher, S., Fjelstrup, S., Côme, C., Ek, S., Kolstad, A., Räty, R., Jerkeman, M., Geisler, C. H.
, Kjems, J., Kristensen, L. S. & Grønbæk, K. (2022).
Expression patterns and prognostic potential of circular RNAs in mantle cell lymphoma: a study of younger patients from the MCL2 and MCL3 clinical trials.
Leukemia,
36(1), 177-188.
https://doi.org/10.1038/s41375-021-01311-4
Gomes-Duarte, A., Venø, M. T., de Wit, M., Senthilkumar, K., Broekhoven, M. H., van den Herik, J., Heeres, F. R., van Rossum, D., Rybiczka-Tesulov, M., Legnini, I., van Rijen, P. C., van Eijsden, P., Gosselaar, P. H., Rajewsky, N.
, Kjems, J., Vangoor, V. R. & Pasterkamp, R. J. (2022).
Expression of Circ_Satb1 Is Decreased in Mesial Temporal Lobe Epilepsy and Regulates Dendritic Spine Morphology.
Frontiers in Molecular Neuroscience,
15, Article 832133.
https://doi.org/10.3389/fnmol.2022.832133
Kristensen, T., Christensen, M. S.
, Jensen, T. H., Kjems, J., Gylling, A. & Scheving, M. (2009).
Experimental Molecular Biology: Laboratory Course Manual.
Knudsen, B., Andersen, E. S.
, Damgaard, C. K., Kjems, J. & Gorodkin, J. (2004).
Evolutionary rate variation and RNA secondary structure prediction.
Computational Biology and Chemistry,
28(3), 219-26.
https://doi.org/10.1016/j.compbiolchem.2004.04.001
Song, J., Li, Q., Wang, X., Li, J., Zhang, S.
, Kjems, J., Besenbacher, F. & Dong, M. (2014).
Evidence of Stranski-Krastanov growth at the initial stage of atmospheric water condensation.
Nature Communications,
5, 1-8. Article 4837.
https://doi.org/10.1038/ncomms5837
Dahl, M.
, Daugaard, I., Andersen, M. S., Hansen, T. B., Grønbæk, K.
, Kjems, J. & Kristensen, L. S. (2018).
Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies.
Laboratory Investigation,
98(12), 1657–1669.
https://doi.org/10.1038/s41374-018-0108-6
Sørensen, R. S., Okholm, A. H., Schaffert, D. H., Kodal, A. L. B.
, Gothelf, K. V. & Kjems, J. (2013).
Enzymatic Ligation of Large Biomolecules to DNA.
ACS Nano,
7(9), 8098-8104.
https://doi.org/10.1021/nn403386f