Torarinsson, E., Yao, Z., Wiklund, E. D.
, Bramsen, J. B., Hansen, C. A.
, Kjems, J., Tommerup, N., Ruzzo, W. L. & Gorodkin, J. (2008).
Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions.
Genome Research,
18(2), 242-251.
https://doi.org/10.1101/gr.6887408
Chen, M., Andersen, M. Ø., Dillschneider, P., Chang, C.-C., Gao, S., Le, D. Q. S., Yang, C., Hein, S., Bünger, C.
& Kjems, J. (2015).
Co-delivery of siRNA and doxorubicin to cancer cells from additively manufactured implants.
RSC Advances,
5, 101718-101725.
https://doi.org/10.1039/C5RA23748C
Scoyni, F., Sitnikova, V., Giudice, L., Korhonen, P., Trevisan, D. M., Hernandez de Sande, A., Gomez-Budia, M., Giniatullina, R., Ugidos, I. F., Dhungana, H., Pistono, C., Korvenlaita, N., Välimäki, N. N., Kangas, S. M., Hiltunen, A. E., Gribchenko, E., Kaikkonen-Määttä, M. U., Koistinaho, J., Ylä-Herttuala, S. ... Malm, T. (2024).
ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling.
Cell Reports,
43(3), Article 113862.
https://doi.org/10.1016/j.celrep.2024.113862
Yan, Y., Wang, X., Venø, M. T., Bakholdt, V., Sørensen, J. A., Krogdahl, A., Sun, Z., Gao, S.
& Kjems, J. (2017).
Circulating miRNAs as biomarkers for oral squamous cell carcinoma recurrence in operated patients.
OncoTarget,
8(5), 8206-8214.
https://doi.org/10.18632/oncotarget.14143
Stoll, L., Sobel, J., Rodriguez-Trejo, A., Guay, C., Lee, K., Venø, M. T.
, Kjems, J., Laybutt, D. R. & Regazzi, R. (2018).
Circular RNAs as novel regulators of β-cell functions in normal and disease conditions.
Molecular Metabolism,
9, 69-83.
https://doi.org/10.1016/j.molmet.2018.01.010
Okholm, T. L. H.
, Nielsen, M. M., Hamilton, M.
, Christensen, L.-L., Vang, S., Hedegaard, J., Hansen, T. B.
, Kjems, J., Dyrskjøt, L. & Pedersen, J. S. (2017).
Circular RNA expression is abundant and correlated to aggressiveness in early-stage bladder cancer.
npj Genomic Medicine,
2(1), Article 36.
https://doi.org/10.1038/s41525-017-0038-z
Tolomeo, D., Traversa, D., Venuto, S., Ebbesen, K.
, Garcia Rodriguez, J. L., Tamma, G., Ranieri, M., Simonetti, G., Ghetti, M., Paganelli, M., Visci, G., Liso, A., Kok, K., Muscarella, L. A., Fabrizio, F. P., Frassanito, M. A., Lamanuzzi, A., Saltarella, I., Solimando, A. G. ... Storlazzi, C. T. (2023).
circPVT1 and PVT1/AKT3 show a role in cell proliferation, apoptosis, and tumor subtype-definition in Small Cell Lung Cancer.
Genes, Chromosomes & Cancer,
62(7), 377-391.
https://doi.org/10.1002/gcc.23121
Okholm, T. L. H., Kamstrup, A. B.
, Nielsen, M. M., Hollensen, A. K., Graversgaard, M. L.
, Kristensen, L. S., Vang, S., Park, S. S., Yeo, G. W.
, Dyrskjøt, L., Kjems, J., Pedersen, J. S. & Damgaard, C. K. (2023).
circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA. bioRxiv
https://doi.org/10.1101/2023.09.14.557527
Yang, C., Nilsson, L., Cheema, M. U., Wang, Y.
, Frøkiær, J., Gao, S.
, Kjems, J. & Nørregaard, R. (2014).
Chitosan/siRNA Nanoparticles Targeting Cyclooxygenase Type 2 Attenuate Unilateral Ureteral Obstruction-induced Kidney Injury in Mice.
Theranostics,
5(2), 110-123.
https://doi.org/10.7150/thno.9717
Chen, M., Gao, S.
, Dong, M., Song, J., Yang, C.
, Howard, K. A., Kjems, J. & Besenbacher, F. (2012).
Chitosan/siRNA nanoparticles encapsulated in PLGA nanofibers for siRNA delivery.
A C S Nano,
6(6), 4835-4844.
https://doi.org/10.1021/nn300106t
Mittnacht, U., Hartmann, H., Hein, S., Oliveira, H.
, Dong, M., Pêgo, A. P.
, Kjems, J., Howard, K. A. & Schlosshauer, B. (2010).
Chitosan/siRNA nanoparticles biofunctionalize nerve implants and enable neurite outgrowth.
Nano Letters,
10(10), 3933-9.
https://doi.org/10.1021/nl1016909
Howard, K. A., Paludan, S. R., Behlke, M. A.
, Besenbacher, F., Deleuran, B. W. & Kjems, J. (2008).
Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model.
Molecular Therapy,
17(1), 162-168.
https://doi.org/10.1038/mt.2008.220
Song, W., Song, X., Yang, C., Gao, S.
, Klausen, L. H., Zhang, Y.
, Dong, M. & Kjems, J. (2015).
Chitosan/siRNA functionalized titanium surface via a layer-by-layer approach for in vitro sustained gene silencing and osteogenic promotion.
International Journal of Nanomedicine (Online),
10, 2335-2346.
https://doi.org/10.2147/IJN.S76513
Louw, A. M., Kolar, M. K., Novikova, L. N., Kingham, P. J., Wiberg, M.
, Kjems, J. & Novikov, L. N. (2016).
Chitosan polyplex mediated delivery of miRNA-124 reduces activation of microglial cells in vitro and in rat models of spinal cord injury.
Nanomedicine: Nanotechnology, Biology and Medicine,
12(3), 643-653.
https://doi.org/10.1016/j.nano.2015.10.011
Ma, Z., Yang, C., Song, W., Wang, Q.
, Kjems, J. & Gao, S. (2014).
Chitosan Hydrogel as siRNA vector for prolonged gene silencing.
Journal of Nanobiotechnology,
12(23), 1-9.
https://doi.org/10.1186/1477-3155-12-23
Vu Quang, H.
, Vinding, M. S., Xia, D.
, Nielsen, T., Ullisch, M. G.
, Dong, M., Nielsen, N. C. & Kjems, J. (2016).
Chitosan-coated Poly(lactic-co-glycolic acid) Perfluorooctyl Bromide Nanoparticles for Cell Labeling in 19F Magnetic Resonance Imaging.
Carbohydrate Polymers,
136, 936-944.
https://doi.org/10.1016/j.carbpol.2015.09.076
Moldovan, L. I., Tsoi, L. C., Ranjitha, U., Hager, H., Weidinger, S., Gudjonsson, J. E.
, Kjems, J. & Kristensen, L. S. (2021).
Characterization of Circular RNA Transcriptomes in Psoriasis and Atopic Dermatitis Reveals Disease-specific Expression Profiles.
Experimental Dermatology,
30(8), 1187-1196.
https://doi.org/10.1111/exd.14227
Sükösd, Z., Knudsen, B., Anderson, J. WJ., Novák, A.
, Kjems, J. & Pedersen, C. N. S. (2013).
Characterising RNA secondary structure space using information entropy.
B M C Bioinformatics,
14 (Suppl 2), 1-9. Article S22.
https://doi.org/10.1186/1471-2105-14-S2-S22
Dupont, D. M., Larsen, N., Jensen, J. K., Andreasen, P. A.
& Kjems, J. (2015).
Characterisation of aptamer-target interactions by branched selection and high-throughput sequencing of SELEX pools.
Nucleic Acids Research,
43(21), 1-13. Article e139.
https://doi.org/10.1093/nar/gkv700
Raniolo, S., Croce, S., Thomsen, R. P., Okholm, A. H., Unida, V., Iacovelli, F., Manetto, A.
, Kjems, J., Desideri, A. & Biocca, S. (2019).
Cellular uptake of covalent and non-covalent DNA nanostructures with different sizes and geometries.
Nanoscale,
11(22), 10808-10818.
https://doi.org/10.1039/c9nr02006c
Vu Quang, H., Chang, C.-C.
, Song, P., Hauge, E. M. & Kjems, J. (2018).
Caveolae-mediated mesenchymal stem cell labelling by PSS-coated PLGA PFOB nano-contrast agent for MRI.
Theranostics,
8(10), 2657-2671.
https://doi.org/10.7150/thno.23206
Hartmann, H., Lakner, U., Andersen, M. Ø.
, Kjems, J., Howard, K. A. & Schloßhauer, B. (2009).
Carrier Matrix for siRNA-Mediated Gene Knock Down to Promote Neuronal Regeneration. Tissue Engineering. Part A. Tissue Engineering, (3), 718.
Lassen, T. R., Just, J., Hjortbak, M. V., Jespersen, N. R., Stenz, K. T., Gu, T., Yan, Y.
, Su, J., Hansen, J., Bæk, R., Jørgensen, M. M.
, Nyengaard, J. R., Kristiansen, S. B., Drasbek, K. R., Kjems, J. & Bøtker, H. E. (2021).
Cardioprotection by remote ischemic conditioning is transferable by plasma and mediated by extracellular vesicles.
Basic Research in Cardiology,
116(1), Article 16.
https://doi.org/10.1007/s00395-021-00856-w
Mukhopadhyay, R., Sumbayev, V. V., Lorentzen, M.
, Kjems, J., Andreasen, P. A.
& Besenbacher, F. (2005).
Cantilever sensor for nanomechanical detection of specific protein conformations.
Nano Letters,
5(12), 2385-8.
https://doi.org/10.1021/nl051449z
Song, W., Yang, C., Svend Le, D. Q., Zhang, Y.
& Kjems, J. (2018).
Calcium-microRNA Complexes Functionalized Nanotubular Implant Surface for Highly Efficient Transfection and Enhanced Osteogenesis of Mesenchymal Stem Cells.
A C S Applied Materials and Interfaces,
10(9), 7756-7764.
https://doi.org/10.1021/acsami.7b18289
Just, J., Yan, Y.
, Farup, J., Sieljacks, P., Sloth, M., Venø, M., Gu, T.
, de Paoli, F. V., Nyengaard, J. R., Bæk, R., Jørgensen, M. M.
, Kjems, J., Vissing, K. & Drasbek, K. R. (2020).
Blood flow-restricted resistance exercise alters the surface profile, miRNA cargo and functional impact of circulating extracellular vesicles.
Scientific Reports,
10(1), Article 5835.
https://doi.org/10.1038/s41598-020-62456-3
Yoshimoto, R.
, Rahimi, K., Hansen, T. B.
, Kjems, J. & Mayeda, A. (2020).
Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats.
iScience,
23(7), Article 101345.
https://doi.org/10.1016/j.isci.2020.101345
Rahbek, U. L.
, Nielsen, A. F., Dong, M., You, Y., Chauchereau, A., Oupicky, D.
, Besenbacher, F., Kjems, J. & Howard, K. A. (2010).
Bioresponsive hyperbranched polymers for siRNA and miRNA delivery.
Journal of Drug Targeting,
18(10), 812-20.
https://doi.org/10.3109/1061186X.2010.527982
Lundin, K. E., Højland, T., Hansen, B., Persson, R.
, Bramsen, J. B., Kjems, J., Koch, T., Wengel, J. & Smith, C. I. E. (2013).
Biological activity and biotechnological aspects of locked nucleic acids.
Advances in Genetics,
82, 47-107.
https://doi.org/10.1016/B978-0-12-407676-1.00002-0
Prabha, R. D.
, Kraft, D. C. E., Harkness, L., Melsen, B., Varma, H., Nair, P. D.
, Kjems, J. & Kassem, M. (2018).
Bioactive Nano-fibrous Scaffold for Vascularized Craniofacial Bone Regeneration.
Journal of Tissue Engineering and Regenerative Medicine,
12(3), e1537-e1548.
https://doi.org/10.1002/term.2579
Hossfeld, S., Nolte, A., Hartmann, H., Recke, M., Schaller, M., Walker, T.
, Kjems, J., Schlosshauer, B., Stoll, D., Wendel, H.-P. & Krastev, R. (2013).
Bioactive coronary stent coating based on layer-by-layer technology for siRNA release.
Acta Biomaterialia,
9(5), 6741-6752.
https://doi.org/10.1016/j.actbio.2013.01.013
Catapano, C., Rahm, J. V.
, Omer, M., Teodori, L., Kjems, J., Dietz, M. S. & Heilemann, M. (2022).
Biased activation of the receptor tyrosine kinase HER2. (pp. 2022.12.04.519064). bioRxiv.
https://doi.org/10.1101/2022.12.04.519064
Catapano, C., Rahm, J. V.
, Omer, M., Teodori, L., Kjems, J., Dietz, M. S. & Heilemann, M. (2023).
Biased activation of the receptor tyrosine kinase HER2.
Cellular and Molecular Life Sciences,
80(6), Article 158.
https://doi.org/10.1007/s00018-023-04806-8
Nielsen, A. F., Bindereif, A., Bozzoni, I., Hanan, M., Hansen, T. B., Irimia, M., Kadener, S.
, Kristensen, L. S., Legnini, I., Morlando, M.
, Olesen, M. T. J., Pasterkamp, R. J., Preibisch, S., Rajewsky, N., Sünkel, C.
& Kjems, J. (2022).
Best practice standards for circular RNA research.
Nature Methods,
19(10), 1208-1220.
https://doi.org/10.1038/s41592-022-01487-2
Ramsay, E., Raviña, M., Sarkhel, S., Hehir, S., Cameron, N. R., Ilmarinen, T., Skottman, H.
, Kjems, J., Urtti, A., Ruponen, M. & Subrizi, A. (2020).
Avoiding the pitfalls of siRNA delivery to the retinal pigment epithelium with physiologically relevant cell models.
Pharmaceutics,
12(7), Article 667.
https://doi.org/10.3390/pharmaceutics12070667
Xu, W., Tan, Q., Yu, M., Sun, Q., Kong, H., Lægsgaard, E., Stensgaard, I.
, Kjems, J., Wang, J., Wang, C.
& Besenbacher, F. (2013).
Atomic-scale structures and interactions between the guanine quartet and potassium.
Chemical Communications,
49(65), 7210-7212.
https://doi.org/10.1039/c3cc43302a
Sun, M., Wang, M., Chen, M., Dagnaes-Hansen, F., Le, D. Q. S., Baatrup, A.
, Horsman, M. R., Kjems, J. & Bünger, C. (2015).
A tissue-engineered therapeutic device inhibits tumor growth in vitro and in vivo.
Acta Biomaterialia,
18, 21-29.
https://doi.org/10.1016/j.actbio.2015.02.004